Modelling the MYC-driven normal-to-tumour switch in breast cancer

by Corey Lourenco, Manpreet Kalkat, Kathleen E. Houlahan, Jason De Melo, Joseph Longo, Susan J. Done, Paul C. Boutros, Linda Z. Penn
Published 2019-07-01

Copy Number Profiles of Prostate Cancer in Men of Middle Eastern Ancestry

by Alia Albawardi, Julie Livingstone, Saeeda Almarzooqi, Nallasivam Palanisamy, Kathleen E. Houlahan, Aktham Adnan Ahmad Awwad, Ramy A. Abdelsalam, Paul C. Boutros, Tarek A. Bismar
Published 2021-05-01

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability

by Dharmendra Dingar, William B. Tu, Diana Resetca, Corey Lourenco, Aaliya Tamachi, Jason De Melo, Kathleen E. Houlahan, Manpreet Kalkat, Pak-Kei Chan, Paul C. Boutros, Brian Raught, Linda Z. Penn
Published 2018-08-01

Germline contamination and leakage in whole genome somatic single nucleotide variant detection

by Dorota H. Sendorek, Cristian Caloian, Kyle Ellrott, J. Christopher Bare, Takafumi N. Yamaguchi, Adam D. Ewing, Kathleen E. Houlahan, Thea C. Norman, Adam A. Margolin, Joshua M. Stuart, Paul C. Boutros
Published 2018-01-01

Valection: design optimization for validation and verification studies

by Christopher I Cooper, Delia Yao, Dorota H Sendorek, Takafumi N Yamaguchi, Christine P’ng, Kathleen E Houlahan, Cristian Caloian, Michael Fraser, SMC-DNA Challenge Participants, Kyle Ellrott, Adam A Margolin, Robert G Bristow, Joshua M Stuart, Paul C Boutros
Published 2018-09-01

Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection

by Anna Y. Lee, Adam D. Ewing, Kyle Ellrott, Yin Hu, Kathleen E. Houlahan, J. Christopher Bare, Shadrielle Melijah G. Espiritu, Vincent Huang, Kristen Dang, Zechen Chong, Cristian Caloian, Takafumi N. Yamaguchi, ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Michael R. Kellen, Ken Chen, Thea C. Norman, Stephen H. Friend, Justin Guinney, Gustavo Stolovitzky, David Haussler, Adam A. Margolin, Joshua M. Stuart, Paul C. Boutros
Published 2018-11-01

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

by Musaddeque Ahmed, Fraser Soares, Ji-Han Xia, Yue Yang, Jing Li, Haiyang Guo, Peiran Su, Yijun Tian, Hyung Joo Lee, Miranda Wang, Nayeema Akhtar, Kathleen E. Houlahan, Almudena Bosch, Stanley Zhou, Parisa Mazrooei, Junjie T. Hua, Sujun Chen, Jessica Petricca, Yong Zeng, Alastair Davies, Michael Fraser, David A. Quigley, Felix Y. Feng, Paul C. Boutros, Mathieu Lupien, Amina Zoubeidi, Liang Wang, Martin J. Walsh, Ting Wang, Shancheng Ren, Gong-Hong Wei, Housheng Hansen He
Published 2021-03-01

BPG: Seamless, automated and interactive visualization of scientific data

by Christine P’ng, Jeffrey Green, Lauren C. Chong, Daryl Waggott, Stephenie D. Prokopec, Mehrdad Shamsi, Francis Nguyen, Denise Y. F. Mak, Felix Lam, Marco A. Albuquerque, Ying Wu, Esther H. Jung, Maud H. W. Starmans, Michelle A. Chan-Seng-Yue, Cindy Q. Yao, Bianca Liang, Emilie Lalonde, Syed Haider, Nicole A. Simone, Dorota Sendorek, Kenneth C. Chu, Nathalie C. Moon, Natalie S. Fox, Michal R. Grzadkowski, Nicholas J. Harding, Clement Fung, Amanda R. Murdoch, Kathleen E. Houlahan, Jianxin Wang, David R. Garcia, Richard de Borja, Ren X. Sun, Xihui Lin, Gregory M. Chen, Aileen Lu, Yu-Jia Shiah, Amin Zia, Ryan Kearns, Paul C. Boutros
Published 2019-01-01