Pioneer of prostate cancer: past, present and the future of FOXA1

by Mona Teng, Stanley Zhou, Changmeng Cai, Mathieu Lupien, Housheng Hansen He
Published 2020-09-01

Refined RIP-seq protocol for epitranscriptome analysis with low input materials.

by Yong Zeng, Shiyan Wang, Shanshan Gao, Fraser Soares, Musadeqque Ahmed, Haiyang Guo, Miranda Wang, Junjie Tony Hua, Jiansheng Guan, Michael F Moran, Ming Sound Tsao, Housheng Hansen He
Published 2018-09-01

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein

by Shuai Gao, Yanfei Gao, Housheng Hansen He, Dong Han, Wanting Han, Amy Avery, Jill A. Macoska, Xiaming Liu, Sen Chen, Fen Ma, Shaoyong Chen, Steven P. Balk, Changmeng Cai
Published 2016-10-01

High-dimensional genomic data bias correction and data integration using MANCIE

by Chongzhi Zang, Tao Wang, Ke Deng, Bo Li, Sheng’en Hu, Qian Qin, Tengfei Xiao, Shihua Zhang, Clifford A. Meyer, Housheng Hansen He, Myles Brown, Jun S. Liu, Yang Xie, X. Shirley Liu
Published 2016-04-01

Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response.

by Rinath M Jeselsohn, Lillian Werner, Meredith M Regan, Aquila Fatima, Lauren Gilmore, Laura C Collins, Andrew H Beck, Shannon T Bailey, Housheng Hansen He, Gilles Buchwalter, Myles Brown, J Dirk Iglehart, Andrea Richardson, Steven E Come
Published 2013-01-01

Lysine-Specific Demethylase 1 Has Dual Functions as a Major Regulator of Androgen Receptor Transcriptional Activity

by Changmeng Cai, Housheng Hansen He, Shuai Gao, Sen Chen, Ziyang Yu, Yanfei Gao, Shaoyong Chen, Mei Wei Chen, Jesse Zhang, Musaddeque Ahmed, Yang Wang, Eric Metzger, Roland Schüle, X. Shirley Liu, Myles Brown, Steven P. Balk
Published 2014-12-01

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

by Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang, Housheng Hansen He, Beverly Torok-Storb, Andrew C. Hsieh, Patrick J. Paddison
Published 2019-10-01

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation

by Zijun Chen, Zhengyang Li, Xiaojian Hu, Feiyan Xie, Siyun Kuang, Bowen Zhan, Wenqing Gao, Xiangjun Chen, Siqi Gao, Yang Li, Yongming Wang, Feng Qian, Chen Ding, Jianhua Gan, Chaoneng Ji, Xue‐Wei Xu, Zheng Zhou, Jinqing Huang, Housheng Hansen He, Jixi Li
Published 2020-07-01

SPOP mutation induces DNA methylation via stabilizing GLP/G9a

by Jianong Zhang, Kun Gao, Hongyan Xie, Dejie Wang, Pingzhao Zhang, Ting Wei, Yuqian Yan, Yunqian Pan, Wenbin Ye, Huifen Chen, Qing Shi, Yao Li, Shi-min Zhao, Xiaonan Hou, Saravut J. Weroha, Yuzhuo Wang, Jun Zhang, R. Jeffrey Karnes, Housheng Hansen He, Liguo Wang, Chenji Wang, Haojie Huang
Published 2021-09-01

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression

by Zhenyue Hao, Yi Sheng, Gordon S. Duncan, Wanda Y. Li, Carmen Dominguez, Jennifer Sylvester, Yu-Wen Su, Gloria H.Y. Lin, Bryan E. Snow, Dirk Brenner, Annick You-Ten, Jillian Haight, Satoshi Inoue, Andrew Wakeham, Alisha Elford, Sara Hamilton, Yi Liang, Juan C. Zúñiga-Pflücker, Housheng Hansen He, Pamela S. Ohashi, Tak W. Mak
Published 2017-01-01

Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes

by Oliver A. Kent, Manipa Saha, Etienne Coyaud, Helen E. Burston, Napoleon Law, Keith Dadson, Sujun Chen, Estelle M. Laurent, Jonathan St-Germain, Ren X. Sun, Yoshinori Matsumoto, Justin Cowen, Aaryn Montgomery-Song, Kevin R. Brown, Charles Ishak, Jose La Rose, Daniel D. De Carvalho, Housheng Hansen He, Brian Raught, Filio Billia, Peter Kannu, Robert Rottapel
Published 2020-09-01

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness

by Jessica SY Ho, Federico Di Tullio, Megan Schwarz, Diana Low, Danny Incarnato, Florence Gay, Tommaso Tabaglio, JingXian Zhang, Heike Wollmann, Leilei Chen, Omer An, Tim Hon Man Chan, Alexander Hall Hickman, Simin Zheng, Vladimir Roudko, Sujun Chen, Alcida Karz, Musaddeque Ahmed, Housheng Hansen He, Benjamin D Greenbaum, Salvatore Oliviero, Michela Serresi, Gaetano Gargiulo, Karen M Mann, Eva Hernando, David Mulholland, Ivan Marazzi, Dave Keng Boon Wee, Ernesto Guccione
Published 2021-06-01

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer

by Stanley Zhou, James R. Hawley, Fraser Soares, Giacomo Grillo, Mona Teng, Seyed Ali Madani Tonekaboni, Junjie Tony Hua, Ken J. Kron, Parisa Mazrooei, Musaddeque Ahmed, Christopher Arlidge, Hwa Young Yun, Julie Livingstone, Vincent Huang, Takafumi N. Yamaguchi, Shadrielle M. G. Espiritu, Yanyun Zhu, Tesa M. Severson, Alex Murison, Sarina Cameron, Wilbert Zwart, Theodorus van der Kwast, Trevor J. Pugh, Michael Fraser, Paul C. Boutros, Robert G. Bristow, Housheng Hansen He, Mathieu Lupien
Published 2020-01-01

CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer

by Musaddeque Ahmed, Fraser Soares, Ji-Han Xia, Yue Yang, Jing Li, Haiyang Guo, Peiran Su, Yijun Tian, Hyung Joo Lee, Miranda Wang, Nayeema Akhtar, Kathleen E. Houlahan, Almudena Bosch, Stanley Zhou, Parisa Mazrooei, Junjie T. Hua, Sujun Chen, Jessica Petricca, Yong Zeng, Alastair Davies, Michael Fraser, David A. Quigley, Felix Y. Feng, Paul C. Boutros, Mathieu Lupien, Amina Zoubeidi, Liang Wang, Martin J. Walsh, Ting Wang, Shancheng Ren, Gong-Hong Wei, Housheng Hansen He
Published 2021-03-01

ONECUT2 is a driver of neuroendocrine prostate cancer

by Haiyang Guo, Xinpei Ci, Musaddeque Ahmed, Junjie Tony Hua, Fraser Soares, Dong Lin, Loredana Puca, Aram Vosoughi, Hui Xue, Estelle Li, Peiran Su, Sujun Chen, Tran Nguyen, Yi Liang, Yuzhe Zhang, Xin Xu, Jing Xu, Anjali V. Sheahan, Wail Ba-Alawi, Si Zhang, Osman Mahamud, Ravi N. Vellanki, Martin Gleave, Robert G. Bristow, Benjamin Haibe-Kains, John T. Poirier, Charles M. Rudin, Ming-Sound Tsao, Bradly G. Wouters, Ladan Fazli, Felix Y. Feng, Leigh Ellis, Theo van der Kwast, Alejandro Berlin, Marianne Koritzinsky, Paul C. Boutros, Amina Zoubeidi, Himisha Beltran, Yuzhuo Wang, Housheng Hansen He
Published 2019-01-01