Analysis of determinants for in vitro resistance to the small molecule deubiquitinase inhibitor b-AP15.

by Arjan Mofers, Paola Perego, Karthik Selvaraju, Laura Gatti, Joachim Gullbo, Stig Linder, Padraig D'Arcy
Published 2019-01-01

Induction of ER Stress in Acute Lymphoblastic Leukemia Cells by the Deubiquitinase Inhibitor VLX1570

by Paola Pellegrini, Karthik Selvaraju, Elena Faustini, Arjan Mofers, Xiaonan Zhang, Jens Ternerot, Alice Schubert, Stig Linder, Pádraig D′Arcy
Published 2020-07-01

Sensitivity of Acute Myelocytic Leukemia Cells to the Dienone Compound VLX1570 Is Associated with Inhibition of the Ubiquitin-Proteasome System

by Karthik Selvaraju, Kourosh Lotfi, Johannes Gubat, Maria Miquel, Amanda Nilsson, Julia Hill, Lasse D. Jensen, Stig Linder, Pádraig D’Arcy
Published 2021-09-01