Targeted De-Methylation of the FOXP3-TSDR Is Sufficient to Induce Physiological FOXP3 Expression but Not a Functional Treg Phenotype

by Christopher Kressler, Christopher Kressler, Gilles Gasparoni, Karl Nordström, Dania Hamo, Dania Hamo, Abdulrahman Salhab, Christoforos Dimitropoulos, Sascha Tierling, Petra Reinke, Petra Reinke, Hans-Dieter Volk, Hans-Dieter Volk, Jörn Walter, Alf Hamann, Julia K. Polansky, Julia K. Polansky, Julia K. Polansky
Published 2021-01-01

Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.

by Jérémie D Goldstein, Aude Burlion, Bruno Zaragoza, Kélhia Sendeyo, Julia K Polansky, Jochen Huehn, Eliane Piaggio, Benoit L Salomon, Gilles Marodon
Published 2016-01-01

reChIP-seq reveals widespread bivalency of H3K4me3 and H3K27me3 in CD4+ memory T cells

by Sarah Kinkley, Johannes Helmuth, Julia K. Polansky, Ilona Dunkel, Gilles Gasparoni, Sebastian Fröhler, Wei Chen, Jörn Walter, Alf Hamann, Ho-Ryun Chung
Published 2016-08-01

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

by Anna Nowak, Dominik Lock, Petra Bacher, Thordis Hohnstein, Katrin Vogt, Judith Gottfreund, Pascal Giehr, Julia K. Polansky, Birgit Sawitzki, Andrew Kaiser, Jörn Walter, Alexander Scheffold, Alexander Scheffold
Published 2018-02-01

A comprehensive analysis of 195 DNA methylomes reveals shared and cell-specific features of partially methylated domains

by Abdulrahman Salhab, Karl Nordström, Gilles Gasparoni, Kathrin Kattler, Peter Ebert, Fidel Ramirez, Laura Arrigoni, Fabian Müller, Julia K. Polansky, Cristina Cadenas, Jan G.Hengstler, Thomas Lengauer, Thomas Manke, DEEP Consortium, Jörn Walter
Published 2018-09-01

Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells

by Kim-Long Truong, Stephan Schlickeiser, Katrin Vogt, David Boës, Katarina Stanko, Christine Appelt, Mathias Streitz, Gerald Grütz, Nadja Stobutzki, Christian Meisel, Christina Iwert, Stefan Tomiuk, Julia K. Polansky, Andreas Pascher, Nina Babel, Ulrik Stervbo, Igor Sauer, Undine Gerlach, Birgit Sawitzki
Published 2019-05-01