Demonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progression.

by Livia Raso-Barnett, Balazs Banky, Tamas Barbai, Peter Becsagh, Jozsef Timar, Erzsebet Raso
Published 2013-01-01

Prognostic Impact of the Neutrophil-to-Lymphocyte and Lymphocyte-to-Monocyte Ratio, in Patients with Rectal Cancer: A Retrospective Study of 1052 Patients

by Zsolt Zoltán Fülöp, Simona Gurzu, Réka Linda Fülöp, Tivadar Bara, József Tímár, Emőke Drágus, Ioan Jung
Published 2020-10-01

Horizontal Combination of MEK and PI3K/mTOR Inhibition in BRAF Mutant Tumor Cells with or without Concomitant PI3K Pathway Mutations

by Dominika Rittler, Eszter Molnár, Marcell Baranyi, Tamás Garay, Luca Hegedűs, Clemens Aigner, József Tóvári, József Tímár, Balázs Hegedűs
Published 2020-10-01

The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction-dependent manner.

by Aniko Keller-Pinter, Bettina Ughy, Monika Domoki, Aladar Pettko-Szandtner, Tamas Letoha, Jozsef Tovari, Jozsef Timar, Laszlo Szilak
Published 2017-01-01

Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells

by Karolina Varga, Anna Hollósi, Katalin Pászty, Luca Hegedűs, Gergely Szakács, József Tímár, Béla Papp, Ágnes Enyedi, Rita Padányi
Published 2018-10-01

Long-Term Vemurafenib Exposure Induced Alterations of Cell Phenotypes in Melanoma: Increased Cell Migration and Its Association with EGFR Expression

by Eszter Molnár, Tamás Garay, Marco Donia, Marcell Baranyi, Dominika Rittler, Walter Berger, József Tímár, Michael Grusch, Balázs Hegedűs
Published 2019-09-01

EGFR Protein Expression in KRAS Wild-Type Metastatic Colorectal Cancer Is Another Negative Predictive Factor of the Cetuximab Therapy

by Andrea Uhlyarik, Violetta Piurko, Zsuzsanna Papai, Erzsebet Raso, Erika Lahm, Edina Kiss, Marta Sikter, Jozsef Vachaja, Istvan Kenessey, Jozsef Timar
Published 2020-03-01

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca2+ Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK

by Luca Hegedüs, Luca Hegedüs, Rita Padányi, Judit Molnár, Katalin Pászty, Karolina Varga, Karolina Varga, István Kenessey, Eszter Sárközy, Matthias Wolf, Michael Grusch, Zoltán Hegyi, László Homolya, Clemens Aigner, Tamás Garay, Balázs Hegedüs, Balázs Hegedüs, József Tímár, József Tímár, Enikö Kállay, Ágnes Enyedi, Ágnes Enyedi
Published 2017-05-01

Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells

by Eszter Molnár, Dominika Rittler, Marcell Baranyi, Michael Grusch, Walter Berger, Balázs Döme, József Tóvári, Clemens Aigner, József Tímár, Tamás Garay, Balázs Hegedűs
Published 2018-05-01

NSCLC molecular testing in Central and Eastern European countries

by Ales Ryska, Peter Berzinec, Luka Brcic, Tanja Cufer, Rafal Dziadziuszko, Maya Gottfried, Ilona Kovalszky, Włodzimierz Olszewski, Buge Oz, Lukas Plank, Jozsef Timar
Published 2018-03-01

The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb

by Dominika Rittler, Marcell Baranyi, Eszter Molnár, Tamás Garay, István Jalsovszky, Imre Károly Varga, Luca Hegedűs, Clemens Aigner, József Tóvári, József Tímár, Balázs Hegedűs
Published 2019-10-01

Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells.

by Tamás Garay, István Kenessey, Eszter Molnár, Éva Juhász, Andrea Réti, Viktória László, Anita Rózsás, Judit Dobos, Balázs Döme, Walter Berger, Walter Klepetko, József Tóvári, József Tímár, Balázs Hegedűs
Published 2015-01-01

A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures

by Miklos Diossy, Zsofia Sztupinszki, Judit Borcsok, Marcin Krzystanek, Viktoria Tisza, Sandor Spisak, Orsolya Rusz, Jozsef Timar, István Csabai, Janos Fillinger, Judit Moldvay, Anders Gorm Pedersen, David Szuts, Zoltan Szallasi
Published 2021-06-01

KRAS Mutations Predict Response and Outcome in Advanced Lung Adenocarcinoma Patients Receiving First-Line Bevacizumab and Platinum-Based Chemotherapy

by Áron Kristof Ghimessy, Áron Gellert, Erzsebet Schlegl, Balazs Hegedus, Erzsebet Raso, Tamas Barbai, Jozsef Timar, Gyula Ostoros, Zsolt Megyesfalvi, Balazs Gieszer, Judit Moldvay, Ferenc Renyi-Vamos, Zoltan Lohinai, Mir Alireza Hoda, Thomas Klikovits, Walter Klepetko, Viktoria Laszlo, Balazs Dome
Published 2019-10-01

The Human Melanoma Proteome Atlas—Complementing the melanoma transcriptome

by Lazaro Hiram Betancourt, Jeovanis Gil, Aniel Sanchez, Viktória Doma, Magdalena Kuras, Jimmy Rodriguez Murillo, Erika Velasquez, Uğur Çakır, Yonghyo Kim, Yutaka Sugihara, Indira Pla Parada, Beáta Szeitz, Roger Appelqvist, Elisabet Wieslander, Charlotte Welinder, Natália Pinto deAlmeida, Nicole Woldmar, Matilda Marko‐Varga, Jonatan Eriksson, Krzysztof Pawłowski, Bo Baldetorp, Christian Ingvar, Håkan Olsson, Lotta Lundgren, Henrik Lindberg, Henriett Oskolas, Boram Lee, Ethan Berge, Marie Sjögren, Carina Eriksson, Dasol Kim, Ho Jeong Kwon, Beatrice Knudsen, Melinda Rezeli, Johan Malm, Runyu Hong, Peter Horvath, A. Marcell Szász, József Tímár, Sarolta Kárpáti, Peter Horvatovich, Tasso Miliotis, Toshihide Nishimura, Harubumi Kato, Erik Steinfelder, Madalina Oppermann, Ken Miller, Francesco Florindi, Quimin Zhou, Gilberto B. Domont, Luciana Pizzatti, Fábio C. S. Nogueira, Leticia Szadai, István Balázs Németh, Henrik Ekedahl, David Fenyö, György Marko‐Varga
Published 2021-07-01

The human melanoma proteome atlas—Defining the molecular pathology

by Lazaro Hiram Betancourt, Jeovanis Gil, Yonghyo Kim, Viktória Doma, Uğur Çakır, Aniel Sanchez, Jimmy Rodriguez Murillo, Magdalena Kuras, Indira Pla Parada, Yutaka Sugihara, Roger Appelqvist, Elisabet Wieslander, Charlotte Welinder, Erika Velasquez, Natália Pinto deAlmeida, Nicole Woldmar, Matilda Marko‐Varga, Krzysztof Pawłowski, Jonatan Eriksson, Beáta Szeitz, Bo Baldetorp, Christian Ingvar, Håkan Olsson, Lotta Lundgren, Henrik Lindberg, Henriett Oskolas, Boram Lee, Ethan Berge, Marie Sjögren, Carina Eriksson, Dasol Kim, Ho Jeong Kwon, Beatrice Knudsen, Melinda Rezeli, Runyu Hong, Peter Horvatovich, Tasso Miliotis, Toshihide Nishimura, Harubumi Kato, Erik Steinfelder, Madalina Oppermann, Ken Miller, Francesco Florindi, Qimin Zhou, Gilberto B. Domont, Luciana Pizzatti, Fábio C. S. Nogueira, Peter Horvath, Leticia Szadai, József Tímár, Sarolta Kárpáti, A. Marcell Szász, Johan Malm, David Fenyö, Henrik Ekedahl, István Balázs Németh, György Marko‐Varga
Published 2021-07-01