Characterization of Disease-Associated Mutations in Human Transmembrane Proteins.

by János Molnár, Gergely Szakács, Gábor E Tusnády
Published 2016-01-01

NGR-peptide-drug conjugates with dual targeting properties.

by Kata Nóra Enyedi, Szilárd Tóth, Gergely Szakács, Gábor Mező
Published 2017-01-01

A novel mathematical model describing adaptive cellular drug metabolism and toxicity in the chemoimmune system.

by Attila Tóth, Anna Brózik, Gergely Szakács, Balázs Sarkadi, Tamás Hegedüs
Published 2015-01-01

Development of novel cyclic NGR peptide–daunomycin conjugates with dual targeting property

by Andrea Angelo Pierluigi Tripodi, Szilárd Tóth, Kata Nóra Enyedi, Gitta Schlosser, Gergely Szakács, Gábor Mező
Published 2018-04-01

Identifying new topoisomerase II poison scaffolds by combining publicly available toxicity data and 2D/3D-based virtual screening

by Anna Lovrics, Veronika F. S. Pape, Dániel Szisz, Adrián Kalászi, Petra Heffeter, Csaba Magyar, Gergely Szakács
Published 2019-11-01

Active transport of rhodamine 123 by the human multidrug transporter P‐glycoprotein involves two independent outer gates

by Fauzia Nasim, Diethart Schmid, Gergely Szakács, Azmat Sohail, Harald H. Sitte, Peter Chiba, Thomas Stockner
Published 2020-04-01

Celecoxib Prevents Doxorubicin-Induced Multidrug Resistance in Canine and Mouse Lymphoma Cell Lines

by Edina Karai, Kornélia Szebényi, Tímea Windt, Sára Fehér, Eszter Szendi, Valéria Dékay, Péter Vajdovich, Gergely Szakács, András Füredi
Published 2020-04-01

A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions.

by Edit Szabó, Dóra Türk, Ágnes Telbisz, Nóra Kucsma, Tamás Horváth, Gergely Szakács, László Homolya, Balázs Sarkadi, György Várady
Published 2018-01-01

Expression of calcium pumps is differentially regulated by histone deacetylase inhibitors and estrogen receptor alpha in breast cancer cells

by Karolina Varga, Anna Hollósi, Katalin Pászty, Luca Hegedűs, Gergely Szakács, József Tímár, Béla Papp, Ágnes Enyedi, Rita Padányi
Published 2018-10-01

Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations.

by Ildikó Kasza, György Várady, Hajnalka Andrikovics, Magdalena Koszarska, Attila Tordai, George L Scheffer, Adrienn Németh, Gergely Szakács, Balázs Sarkadi
Published 2012-01-01

Relation of Metal-Binding Property and Selective Toxicity of 8-Hydroxyquinoline Derived Mannich Bases Targeting Multidrug Resistant Cancer Cells

by Veronika F.S. Pape, Anikó Gaál, István Szatmári, Nóra Kucsma, Norbert Szoboszlai, Christina Streli, Ferenc Fülöp, Éva A. Enyedy, Gergely Szakács
Published 2021-01-01

Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes.

by Katalin Kiss, Anna Brozik, Nora Kucsma, Alexandra Toth, Melinda Gera, Laurence Berry, Alice Vallentin, Henri Vial, Michel Vidal, Gergely Szakacs
Published 2012-01-01

Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.

by Katalin Goda, Yaprak Dönmez-Cakil, Szabolcs Tarapcsák, Gábor Szalóki, Dániel Szöllősi, Zahida Parveen, Dóra Türk, Gergely Szakács, Peter Chiba, Thomas Stockner
Published 2020-10-01

Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance

by Szilárd Tóth, Áron Szepesi, Viet-Khoa Tran-Nguyen, Balázs Sarkadi, Katalin Német, Pierre Falson, Attilio Di Pietro, Gergely Szakács, Ahcène Boumendjel
Published 2020-02-01

Establishment and Characterization of a Brca1^−/−, p53^−/− Mouse Mammary Tumor Cell Line

by Lilla Hámori, Gyöngyi Kudlik, Kornélia Szebényi, Nóra Kucsma, Bálint Szeder, Ádám Póti, Ferenc Uher, György Várady, Dávid Szüts, József Tóvári, András Füredi, Gergely Szakács
Published 2020-02-01

Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals.

by Magdalena Koszarska, Nora Kucsma, Katalin Kiss, Gyorgy Varady, Melinda Gera, Geza Antalffy, Hajnalka Andrikovics, Attila Tordai, Maciej Studzian, Dominik Strapagiel, Lukasz Pulaski, Yoshihiko Tani, Balazs Sarkadi, Gergely Szakacs
Published 2014-01-01

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

by Ádám Póti, Hella Gyergyák, Eszter Németh, Orsolya Rusz, Szilárd Tóth, Csenger Kovácsházi, Dan Chen, Bernadett Szikriszt, Sándor Spisák, Shunichi Takeda, Gergely Szakács, Zoltan Szallasi, Andrea L. Richardson, Dávid Szüts
Published 2019-11-01

Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

by Anikó Gaál, Tamás M. Garay, Ildikó Horváth, Domokos Máthé, Dávid Szöllősi, Dániel S. Veres, Jeremiah Mbuotidem, Tibor Kovács, József Tóvári, Ralf Bergmann, Christina Streli, Gergely Szakács, Judith Mihály, Zoltán Varga, Norbert Szoboszlai
Published 2020-05-01

Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters.

by Csilla Temesszentandrási-Ambrus, Szilárd Tóth, Rinkee Verma, Péter Bánhegyi, István Szabadkai, Ferenc Baska, Csaba Szántai-Kis, Ruben C Hartkoorn, Mary A Lingerfelt, Balázs Sarkadi, Gergely Szakács, László Őrfi, Valakunja Nagaraja, Sean Ekins, Ágnes Telbisz
Published 2018-01-01