Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions

by Ho Jeong Kwon, Peter Karuso
Published 2018-01-01

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

by Michael P. Gotsbacher, Sungmin Cho, Ho Jeong Kwon, Peter Karuso
Published 2017-07-01

Convallatoxin, a dual inducer of autophagy and apoptosis, inhibits angiogenesis in vitro and in vivo.

by Seung Ya Yang, Nam Hee Kim, Yoon Sun Cho, Hukeun Lee, Ho Jeong Kwon
Published 2014-01-01

Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center

by Johan Malm, Yutaka Sugihara, Marcell Szasz, Ho Jeong Kwon, Henrik Lindberg, Roger Appelqvist, György Marko-Varga
Published 2018-08-01

Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction

by Dasol Kim, Hui-Yun Hwang, Eun Sun Ji, Jin Young Kim, Jong Shin Yoo, Ho Jeong Kwon
Published 2021-01-01

Activation of Ca2+‐AMPK‐mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts

by Dasol Kim, Kyeong Eun Yang, Dong Won Kim, Hui‐Yun Hwang, Jinyoung Kim, Jong‐Soon Choi, Ho Jeong Kwon
Published 2021-08-01

Matrix‐assisted laser desorption ionization ‐ mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non‐small‐cell lung cancer mouse xenograft mod...

by Tae Young Kim, Boram Lee, Yonghyo Kim, Yutaka Sugihara, Melinda Rezeli, A. Marcell Szasz, Balazs Dome, Gyorgy Marko‐Varga, Ho Jeong Kwon
Published 2021-07-01

Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment

by Hui-Yun Hwang, Yoon Sun Cho, Jin Young Kim, Ki Na Yun, Jong Shin Yoo, Eunhyeong Lee, Injune Kim, Ho Jeong Kwon
Published 2020-02-01

Proteomic analysis enables distinction of early‐ versus advanced‐stage lung adenocarcinomas

by Olga Kelemen, Indira Pla, Aniel Sanchez, Melinda Rezeli, Attila Marcell Szasz, Johan Malm, Viktoria Laszlo, Ho Jeong Kwon, Balazs Dome, Gyorgy Marko‐Varga
Published 2020-06-01

Endogenous expression mapping of malignant melanoma by mass spectrometry imaging

by Yutaka Sugihara, Daniel Rivas, Johan Malm, Marcell Szasz, HoJeong Kwon, Bo Baldetorp, Håkan Olsson, Christian Ingvar, Melinda Rezeli, Thomas E. Fehniger, György Marko-Varga
Published 2018-08-01

DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer

by Tae Young Kim, Eun Sun Ji, Ju Yeon Lee, Jin Young Kim, Jong Shin Yoo, A. Marcell Szasz, Balazs Dome, Gyorgy Marko-Varga, Ho Jeong Kwon
Published 2020-09-01

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress

by Hwa-Young Lee, Seung-Wook Kim, Geum-Hwa Lee, Min-Kyung Choi, Han-Wool Chung, Yong-Chul Lee, Hyung-Ryong Kim, Ho Jeong Kwon, Han-Jung Chae
Published 2017-07-01

Two cyclic hexapeptides from Penicillium sp. FN070315 with antiangiogenic activities.

by Jun-Pil Jang, Hye Jin Jung, Jang Mi Han, Narae Jung, Yonghyo Kim, Ho Jeong Kwon, Sung-Kyun Ko, Nak-Kyun Soung, Jae-Hyuk Jang, Jong Seog Ahn
Published 2017-01-01

Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin

by Ik-Soon Jang, Eunbi Jo, Soo Jung Park, Su Jeong Baek, In-Hu Hwang, Hyun Mi Kang, Je-Ho Lee, Joseph Kwon, Junik Son, Ho Jeong Kwon, Jong-Soon Choi
Published 2020-01-01

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

by Hyejin Lim, Yu-Mi Lim, Kook Hwan Kim, Young Eui Jeon, Kihyoun Park, Jinyoung Kim, Hui-Yun Hwang, Dong Jin Lee, Haushabhau Pagire, Ho Jeong Kwon, Jin Hee Ahn, Myung-Shik Lee
Published 2018-04-01

Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI

by Yonghyo Kim, Yutaka Sugihara, Tae Young Kim, Sung Min Cho, Jin Young Kim, Ju Yeon Lee, Jong Shin Yoo, Doona Song, Gyoonhee Han, Melinda Rezeli, Charlotte Welinder, Roger Appelqvist, György Marko-Varga, Ho Jeong Kwon
Published 2020-03-01

Identification of a novel sulfonamide non-nucleoside reverse transcriptase inhibitor by a phenotypic HIV-1 full replication assay.

by Tae-Hee Kim, Yoonae Ko, Thierry Christophe, Jonathan Cechetto, Junwon Kim, Kyoung-Ae Kim, Annette S Boese, Jean-Michel Garcia, Denis Fenistein, Moon Kyeong Ju, Junghwan Kim, Sung-Jun Han, Ho Jeong Kwon, Vincent Brondani, Peter Sommer
Published 2013-01-01

A biobanking turning‐point in the use of formalin‐fixed, paraffin tumor blocks to unveil kinase signaling in melanoma

by Erika Velasquez, Leticia Szadai, Qimin Zhou, Yonghyo Kim, Indira Pla, Aniel Sanchez, Roger Appelqvist, Henriett Oskolas, Matilda Marko‐Varga, Boram Lee, Ho Jeong Kwon, Johan Malm, Attila Marcell Szász, Jeovanis Gil, Lazaro Hiram Betancourt, István Balázs Németh, György Marko‐Varga
Published 2021-08-01

Protein Expression in Metastatic Melanoma and the Link to Disease Presentation in a Range of Tumor Phenotypes

by Yonghyo Kim, Jeovanis Gil, Indira Pla, Aniel Sanchez, Lazaro Hiram Betancourt, Boram Lee, Roger Appelqvist, Christian Ingvar, Lotta Lundgren, Håkan Olsson, Bo Baldetorp, Ho Jeong Kwon, Henriett Oskolás, Melinda Rezeli, Viktoria Doma, Sarolta Kárpáti, A. Marcell Szasz, István Balázs Németh, Johan Malm, György Marko-Varga
Published 2020-03-01

The Human Melanoma Proteome Atlas—Complementing the melanoma transcriptome

by Lazaro Hiram Betancourt, Jeovanis Gil, Aniel Sanchez, Viktória Doma, Magdalena Kuras, Jimmy Rodriguez Murillo, Erika Velasquez, Uğur Çakır, Yonghyo Kim, Yutaka Sugihara, Indira Pla Parada, Beáta Szeitz, Roger Appelqvist, Elisabet Wieslander, Charlotte Welinder, Natália Pinto deAlmeida, Nicole Woldmar, Matilda Marko‐Varga, Jonatan Eriksson, Krzysztof Pawłowski, Bo Baldetorp, Christian Ingvar, Håkan Olsson, Lotta Lundgren, Henrik Lindberg, Henriett Oskolas, Boram Lee, Ethan Berge, Marie Sjögren, Carina Eriksson, Dasol Kim, Ho Jeong Kwon, Beatrice Knudsen, Melinda Rezeli, Johan Malm, Runyu Hong, Peter Horvath, A. Marcell Szász, József Tímár, Sarolta Kárpáti, Peter Horvatovich, Tasso Miliotis, Toshihide Nishimura, Harubumi Kato, Erik Steinfelder, Madalina Oppermann, Ken Miller, Francesco Florindi, Quimin Zhou, Gilberto B. Domont, Luciana Pizzatti, Fábio C. S. Nogueira, Leticia Szadai, István Balázs Németh, Henrik Ekedahl, David Fenyö, György Marko‐Varga
Published 2021-07-01