Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA

by Joung, Julia, Ladha, Alim, Jin, Xin, Gootenberg, Jonathan S, Abudayyeh, Omar O., Zhang, Feng
Published 2021

Orthogonal gene knockout and activation with a catalytically active Cas9 nuclease

by Joung, Julia, Zhang, Feng, Konermann, Silvana, Dahlman, James E., Abudayyeh, Omar Osama, Gootenberg, Jonathan S.
Published 2016

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

by Kellner, Max J., Gootenberg, Jonathan S, Joung, Julia, Collins, James J., Zhang, Feng, Abudayyeh, Omar O.
Published 2018

RNA editing with CRISPR-Cas13

by Cox, David Benjamin Turitz, Gootenberg, Jonathan S., Abudayyeh, Omar O., Franklin, Brian, Kellner, Max J., Joung, Julia, Zhang, Feng
Published 2020

High-resolution interrogation of functional elements in the noncoding genome

by Fontanillas, P., Sanjana, Neville E, Wright, Jason, Zheng, Kaijie, Shalem, Ophir, Joung, Julia, Cheng, Chia-Wei, Regev, Aviv, Zhang, Feng
Published 2017

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

by Joung, Julia, Konermann, Silvana M, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Platt, Randall Jeffrey, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng
Published 2017

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma

by Nie, Man, Du, Likun, Ren, Weicheng, Joung, Julia, Ye, Xiaofei, Shi, Xi, Ciftci, Sibel, Liu, Dongbing, Wu, Kui, Zhang, Feng, Pan-Hammarström, Qiang
Published 2021

A cytosine deaminase for programmable single-base RNA editing

by Abudayyeh, Omar O., Gootenberg, Jonathan S, Franklin, Brian, Koob, Jeremy, Kellner, Max J., Ladha, Alim, Joung, Julia, Kirchgatterer, Paul, Cox, David B. T., Zhang, Feng
Published 2020

Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems

by Shmakov, Sergey, Makarova, Kira S, Wolf, Yuri I, Semenova, Ekaterina, Minakhin, Leonid, Severinov, Konstantin, Koonin, Eugene V, Abudayyeh, Omar Osama, Gootenberg, Jonathan S, Joung, Julia, Konermann, Silvana M, Zhang, Feng
Published 2017

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

by Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng, Abudayyeh, Omar Osama
Published 2016

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

by Makarova, Kira S, van der Oost, John, Koonin, Eugene V, Zetsche, Bernd, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Slaymaker, Ian, Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, Regev, Aviv, Zhang, Feng
Published 2016

Application of CRISPR genetic screens to investigate neurological diseases

by So, Raphaella W L, Chung, Sai W, Lau, Heather H C, Watts, Jeremy J, Gaudette, Erin, Al-Azzawi, Zaid A M, Bishay, Jossana, Lin, Lilian T, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold
Published 2020

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

by Shmakov, S., Makarova, K. S., Semenova, E., Minakhin, L., Severinov, K., Koonin, E. V., Regev, Aviv, Gootenberg, Jonathan S, Konermann, Silvana M, Joung, Julia, Slaymaker, Ian, Cox, David Benjamin Turitz, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O.
Published 2016

RNA targeting with CRISPR-Cas13

by Essletzbichler, Patrick, Belanto, Joseph J., Verdine, Vanessa, Kellner, Max J., Voytas, Daniel F., Gootenberg, Jonathan S, Han, Shuo, Joung, Julia, Cox, David Benjamin Turitz, Regev, Aviv, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O., Ting, Alice Y.
Published 2018

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

by Verdine, Vanessa K., Aguet, Francois, Fulco, Charles P., Tseng, Yuen-Yi, Boehm, Jesse S., Joung, Julia, Engreitz, Jesse Michael, Konermann, Silvana M, Gootenberg, Jonathan S, Sanjana, Neville E, Wright, Jason, Yoon, Charles, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O.
Published 2018

Rapid SARS-CoV-2 testing in primary material based on a novel multiplex RT-LAMP assay

by Schermer, Bernhard, Fabretti, Francesca, Damagnez, Maximilian, Di Cristanziano, Veronica, Heger, Eva, Arjune, Sita, Tanner, Nathan A., Imhof, Thomas, Koch, Manuel, Ladha, Alim, Joung, Julia, Gootenberg, Jonathan S, Abudayyeh, Omar O., Burst, Volker, Zhang, Feng, Klein, Florian, Benzing, Thomas, Müller, Roman-Ulrich
Published 2020

Nucleic acid detection with CRISPR-Cas13a/C2c2

by Lee, Jeong Wook, Essletzbichler, Patrick, Verdine, Vanessa, Donghia, Nina, Freije, Catherine A., Myhrvold, Cameron, Bhattacharyya, Roby P., Livny, Jonathan, Koonin, Eugene V., Pardis, C. Sabeti, Gootenberg, Jonathan S, Dy, Aaron James, Joung, Julia, Daringer, Nichole Marie, Regev, Aviv, Hung, Deborah T, Collins, James J., Zhang, Feng, Abudayyeh, Omar O.
Published 2017