Structural basis for the altered PAM recognition by engineered CRISPR-Cpf1

by Nishimasu, Hiroshi, Yamano, Takashi, Gao, Linyi, Zhang, Feng, Ishitani, Ryuichiro, Nureki, Osamu
Published 2020

Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

by Yamano, Takashi, Zetsche, Bernd, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu
Published 2020

Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9

by Hirano, Seiichi, Abudayyeh, Omar O., Gootenberg, Jonathan S, Horii, Takuro, Ishitani, Ryuichiro, Hatada, Izuho, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu
Published 2019

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

by Nishimasu, Hiroshi, Dohmae, Naoshi, Ishitani, Ryuichiro, Nureki, Osamu, Ran, Fei, Hsu, Patrick, Konermann, Silvana M, Shehata, Soraya I., Zhang, Feng
Published 2017

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

by Nishimasu, Hiroshi, Dohmae, Naoshi, Ishitani, Ryuichiro, Nureki, Osamu, Ran, Fei, Hsu, Patrick, Konermann, Silvana M, Shehata, Soraya I., Zhang, Feng
Published 2017

Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems

by Yamada, Mari, Watanabe, Yuto, Hirano, Hisato, Ran, F. Ann, Nakane, Takanori, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nureki, Osamu, Gootenberg, Jonathan S, Zhang, Feng
Published 2018

Crystal Structure of Staphylococcus aureus Cas9

by Nishimasu, Hiroshi, Ran, F. Ann, Kurabayashi, Arisa, Ishitani, Ryuichiro, Nureki, Osamu, Cong, Le, Yan, Winston Xia, Zetsche, Bernd, Li, Yinqing, Zhang, Feng
Published 2017

Structure and Engineering of Francisella novicida Cas9

by Hirano, Hisato, Horii, Takuro, Kimura, Mika, Nakane, Takanori, Ishitani, Ryuichiro, Hatada, Izuho, Nishimasu, Hiroshi, Nureki, Osamu, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Hsu, Patrick, Zhang, Feng
Published 2017

Engineered Cpf1 variants with altered PAM specificities

by Schneider, Martin W, Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Gao, Linyi, Cox, David Benjamin Turitz, Yan, Winston Xia, Manteiga, John Colonnese, Zhang, Feng
Published 2018

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

by Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng, Abudayyeh, Omar Osama
Published 2016

Engineered CRISPR-Cas9 nuclease with expanded targeting space

by Nishimasu, Hiroshi, Shi, Xi, Ishiguro, Soh, Gao, Linyi, Hirano, Seiichi, Okazaki, Sae, Noda, Taichi, Abudayyeh, Omar O., Gootenberg, Jonathan S, Mori, Hideto, Oura, Seiya, Holmes, Benjamin Ray, Tanaka, Mamoru, Seki, Motoaki, Hirano, Hisato, Aburatani, Hiroyuki, Ishitani, Ryuichiro, Ikawa, Masahito, Yachie, Nozomu, Zhang, Feng, Nureki, Osamu, Zhang, Feng
Published 2020