Extraordinary effects of unnatural pairings

by Alejandro Villarino, John J O'Shea
Published 2017-05-01

Epigenomic Views of Innate Lymphoid Cells

by Giuseppe Sciumè, Han-Yu Shih, Yohei Mikami, John J. O’Shea
Published 2017-11-01

Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes

by Nilisha Fernando, Giuseppe Sciumè, John J. O’Shea, Han-Yu Shih, Han-Yu Shih
Published 2021-03-01

PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond.

by Paul W Bible, Yuka Kanno, Lai Wei, Stephen R Brooks, John J O'Shea, Maria I Morasso, Rasiah Loganantharaj, Hong-Wei Sun
Published 2015-01-01

Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells

by Gabriela M. Wiedemann, Simon Grassmann, Colleen M. Lau, Moritz Rapp, Alejandro V. Villarino, Christin Friedrich, Georg Gasteiger, John J. O’Shea, Joseph C. Sun
Published 2020-12-01

Tissue inhibitor of metalloproteinase 1 is preferentially expressed in Th1 and Th17 T-helper cell subsets and is a direct STAT target gene.

by Adewole Adamson, Kamran Ghoreschi, Matthew Rittler, Qian Chen, Hong-Wei Sun, Golnaz Vahedi, Yuka Kanno, William G Stetler-Stevenson, John J O'Shea, Arian Laurence
Published 2013-01-01

The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1

by Stefania Dell’Orso, A. Hongjun Wang, Han-Yu Shih, Kayoko Saso, Libera Berghella, Gustavo Gutierrez-Cruz, Andreas G. Ladurner, John J. O’Shea, Vittorio Sartorelli, Hossein Zare
Published 2016-02-01

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions

by Alejandro Villarino, Arian Laurence, Gertraud W Robinson, Michael Bonelli, Barbara Dema, Behdad Afzali, Han-Yu Shih, Hong-Wei Sun, Stephen R Brooks, Lothar Hennighausen, Yuka Kanno, John J O'Shea
Published 2016-03-01

JAK Inhibition Differentially Affects NK Cell and ILC1 Homeostasis

by Laura Vian, Mimi T. Le, Nathalia Gazaniga, Jacqueline Kieltyka, Christine Liu, Giuseppe Pietropaolo, Stefania Dell'Orso, Stephen R. Brooks, Yasuko Furumoto, Craig J. Thomas, Craig J. Thomas, John J. O'Shea, Giuseppe Sciumè, Massimo Gadina
Published 2019-12-01

Environmental arginine controls multinuclear giant cell metabolism and formation

by Julia S. Brunner, Loan Vulliard, Melanie Hofmann, Markus Kieler, Alexander Lercher, Andrea Vogel, Marion Russier, Johanna B. Brüggenthies, Martina Kerndl, Victoria Saferding, Birgit Niederreiter, Alexandra Junza, Annika Frauenstein, Carina Scholtysek, Yohei Mikami, Kristaps Klavins, Gerhard Krönke, Andreas Bergthaler, John J. O’Shea, Thomas Weichhart, Felix Meissner, Josef S. Smolen, Paul Cheng, Oscar Yanes, Jörg Menche, Peter J. Murray, Omar Sharif, Stephan Blüml, Gernot Schabbauer
Published 2020-01-01

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells

by Bernard Khor, John D Gagnon, Gautam Goel, Marly I Roche, Kara L Conway, Khoa Tran, Leslie N Aldrich, Thomas B Sundberg, Alison M Paterson, Scott Mordecai, David Dombkowski, Melanie Schirmer, Pauline H Tan, Atul K Bhan, Rahul Roychoudhuri, Nicholas P Restifo, John J O'Shea, Benjamin D Medoff, Alykhan F Shamji, Stuart L Schreiber, Arlene H Sharpe, Stanley Y Shaw, Ramnik J Xavier
Published 2015-05-01

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

by Sarfaraz A. Hasni, Sarthak Gupta, Michael Davis, Elaine Poncio, Yenealem Temesgen-Oyelakin, Philip M. Carlucci, Xinghao Wang, Mohammad Naqi, Martin P. Playford, Rishi R. Goel, Xiaobai Li, Ann J. Biehl, Isabel Ochoa-Navas, Zerai Manna, Yinghui Shi, Donald Thomas, Jinguo Chen, Angélique Biancotto, Richard Apps, Foo Cheung, Yuri Kotliarov, Ashley L. Babyak, Huizhi Zhou, Rongye Shi, Katie Stagliano, Wanxia Li Tsai, Laura Vian, Nathalia Gazaniga, Valentina Giudice, Shajia Lu, Stephen R. Brooks, Meggan MacKay, Peter Gregersen, Nehal N. Mehta, Alan T. Remaley, Betty Diamond, John J. O’ Shea, Massimo Gadina, Mariana J. Kaplan
Published 2021-06-01