BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy

by Peter M. Brownlee, Anna L. Chambers, Ross Cloney, Alessandro Bianchi, Jessica A. Downs
Published 2014-03-01

Defining Signatures of Arm-Wise Copy Number Change and Their Associated Drivers in Kidney Cancers

by Graeme Benstead-Hume, Sarah K. Wooller, Jessica A Downs, Frances M. G. Pearl
Published 2019-11-01

The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses.

by Anna L Chambers, Peter M Brownlee, Samuel C Durley, Tracey Beacham, Nicholas A Kent, Jessica A Downs
Published 2012-01-01

Predicting synthetic lethal interactions using conserved patterns in protein interaction networks.

by Graeme Benstead-Hume, Xiangrong Chen, Suzanna R Hopkins, Karen A Lane, Jessica A Downs, Frances M G Pearl
Published 2019-04-01

TP53 modulates radiotherapy fraction size sensitivity in normal and malignant cells

by Selvakumar Anbalagan, Cecilia Ström, Jessica A. Downs, Penny A. Jeggo, David McBay, Anna Wilkins, Kai Rothkamm, Kevin J. Harrington, John R. Yarnold, Navita Somaiah
Published 2021-03-01

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

by Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, Martijn S. Luijsterburg, Ralph Imhof, Jessica A. Downs, Alfred C. O. Vertegaal, Sébastien Huet, Matthias Altmeyer, Haico van Attikum
Published 2020-11-01

Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside

by Sijia Tao, Keivan Zandi, Leda Bassit, Yee Tsuey Ong, Kiran Verma, Peng Liu, Jessica A. Downs-Bowen, Tamara McBrayer, Julia C. LeCher, James J. Kohler, Philip R. Tedbury, Baek Kim, Franck Amblard, Stefan G. Sarafianos, Raymond F. Schinazi
Published 2021-01-01