The Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency

by Marco Gatti, Ralph Imhof, Qingyao Huang, Michael Baudis, Matthias Altmeyer
Published 2020-08-01

Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

by Stefania Pellegrino, Jone Michelena, Federico Teloni, Ralph Imhof, Matthias Altmeyer
Published 2017-05-01

Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance

by Jone Michelena, Aleksandra Lezaja, Federico Teloni, Thomas Schmid, Ralph Imhof, Matthias Altmeyer
Published 2018-07-01

RPA shields inherited DNA lesions for post-mitotic DNA synthesis

by Aleksandra Lezaja, Andreas Panagopoulos, Yanlin Wen, Edison Carvalho, Ralph Imhof, Matthias Altmeyer
Published 2021-06-01

A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

by Akshay K. Ahuja, Karolina Jodkowska, Federico Teloni, Anna H. Bizard, Ralph Zellweger, Raquel Herrador, Sagrario Ortega, Ian D. Hickson, Matthias Altmeyer, Juan Mendez, Massimo Lopes
Published 2016-02-01

Sequential role of RAD51 paralog complexes in replication fork remodeling and restart

by Matteo Berti, Federico Teloni, Sofija Mijic, Sebastian Ursich, Jevgenij Fuchs, Maria Dilia Palumbieri, Jana Krietsch, Jonas A. Schmid, Edwige B. Garcin, Stéphanie Gon, Mauro Modesti, Matthias Altmeyer, Massimo Lopes
Published 2020-07-01

CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks

by Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, Martijn S. Luijsterburg, Ralph Imhof, Jessica A. Downs, Alfred C. O. Vertegaal, Sébastien Huet, Matthias Altmeyer, Haico van Attikum
Published 2020-11-01