In vitro Modeling of Embryonal Tumors

by Lars Custers, Lars Custers, Irene Paassen, Irene Paassen, Jarno Drost, Jarno Drost
Published 2021-02-01

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

by Carla S Verissimo, René M Overmeer, Bas Ponsioen, Jarno Drost, Sander Mertens, Ingrid Verlaan-Klink, Bastiaan van Gerwen, Marieke van der Ven, Marc van de Wetering, David A Egan, René Bernards, Hans Clevers, Johannes L Bos, Hugo J Snippert
Published 2016-11-01

Prognostic Factors for Wilms Tumor Recurrence: A Review of the Literature

by Alissa Groenendijk, Filippo Spreafico, Ronald R. de Krijger, Jarno Drost, Jesper Brok, Daniela Perotti, Harm van Tinteren, Rajkumar Venkatramani, Jan Godziński, Christian Rübe, James I. Geller, Norbert Graf, Marry M. van den Heuvel-Eibrink, Annelies M. C. Mavinkurve-Groothuis
Published 2021-06-01

Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

by Justine N. van der Beek, James I. Geller, Ronald R. de Krijger, Norbert Graf, Kathy Pritchard-Jones, Jarno Drost, Arnauld C. Verschuur, Dermot Murphy, Satyajit Ray, Filippo Spreafico, Kristina Dzhuma, Annemieke S. Littooij, Barbara Selle, Godelieve A. M. Tytgat, Marry M. van den Heuvel-Eibrink
Published 2020-07-01

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

by Camilla Calandrini, Sander R. van Hooff, Irene Paassen, Dilara Ayyildiz, Sepide Derakhshan, M. Emmy M. Dolman, Karin P.S. Langenberg, Marieke van de Ven, Cecilia de Heus, Nalan Liv, Marcel Kool, Ronald R. de Krijger, Godelieve A.M. Tytgat, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Jarno Drost
Published 2021-08-01

Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours

by Lars Custers, Eleonora Khabirova, Tim H. H. Coorens, Thomas R. W. Oliver, Camilla Calandrini, Matthew D. Young, Felipe A. Vieira Braga, Peter Ellis, Lira Mamanova, Heidi Segers, Arie Maat, Marcel Kool, Eelco W. Hoving, Marry M. van den Heuvel-Eibrink, James Nicholson, Karin Straathof, Liz Hook, Ronald R. de Krijger, Claire Trayers, Kieren Allinson, Sam Behjati, Jarno Drost
Published 2021-03-01

Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cells

by Iris E Glykofridis, Jaco C Knol, Jesper A Balk, Denise Westland, Thang V Pham, Sander R Piersma, Sinéad M Lougheed, Sepide Derakhshan, Puck Veen, Martin A Rooimans, Saskia E van Mil, Franziska Böttger, Pino J Poddighe, Irma van de Beek, Jarno Drost, Fried JT Zwartkruis, Renee X de Menezes, Hanne EJ Meijers-Heijboer, Arjan C Houweling, Connie R Jimenez, Rob MF Wolthuis
Published 2021-01-01

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

by Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, Emmy Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten Rookmaaker, Marianne Verhaar, Godelieve A. M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al-Saadi, Kathy Pritchard-Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost
Published 2020-03-01

Single cell derived mRNA signals across human kidney tumors

by Matthew D. Young, Thomas J. Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez, Kwasi Kwakwa, Eleonora Khabirova, Gerda Kildisiute, Thomas R. W. Oliver, Ronald R. de Krijger, Marry M. van den Heuvel-Eibrink, Federico Comitani, Alice Piapi, Eva Bugallo-Blanco, Christine Thevanesan, Christina Burke, Elena Prigmore, Kirsty Ambridge, Kenny Roberts, Felipe A. Vieira Braga, Tim H. H. Coorens, Ignacio Del Valle, Anna Wilbrey-Clark, Lira Mamanova, Grant D. Stewart, Vincent J. Gnanapragasam, Dyanne Rampling, Neil Sebire, Nicholas Coleman, Liz Hook, Anne Warren, Muzlifah Haniffa, Marcel Kool, Stefan M. Pfister, John C. Achermann, Xiaoling He, Roger A. Barker, Adam Shlien, Omer A. Bayraktar, Sarah A. Teichmann, Frank C. Holstege, Kerstin B. Meyer, Jarno Drost, Karin Straathof, Sam Behjati
Published 2021-06-01