The Potential of Mesenchymal Stromal Cells in Neuroblastoma Therapy for Delivery of Anti-Cancer Agents and Hematopoietic Recovery

by Caroline Hochheuser, Nina Y. Kunze, Godelieve A. M. Tytgat, Carlijn Voermans, Ilse Timmerman
Published 2021-02-01

Selective serotonin reuptake inhibitors (SSRIs) prevent meta-iodobenzylguanidine (MIBG) uptake in platelets without affecting neuroblastoma tumor uptake

by Thomas Blom, Rutger Meinsma, Marja Rutgers, Corine Buitenhuis, Marieke Dekken-Van den Burg, André B. P. van Kuilenburg, Godelieve A. M. Tytgat
Published 2020-07-01

Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocy...

by Thomas Blom, Rutger Meinsma, Franca di Summa, Emile van den Akker, André B. P. van Kuilenburg, Marten Hansen, Godelieve A. M. Tytgat
Published 2021-08-01

The Metastatic Bone Marrow Niche in Neuroblastoma: Altered Phenotype and Function of Mesenchymal Stromal Cells

by Caroline Hochheuser, Lieke M. J. van Zogchel, Marion Kleijer, Carlijn Kuijk, Simon Tol, C. Ellen van der Schoot, Carlijn Voermans, Godelieve A. M. Tytgat, Ilse Timmerman
Published 2020-11-01

Nuclear Medicine Imaging in Neuroblastoma: Current Status and New Developments

by Atia Samim, Godelieve A.M. Tytgat, Gitta Bleeker, Sylvia T.M. Wenker, Kristell L.S. Chatalic, Alex J. Poot, Nelleke Tolboom, Max M. van Noesel, Marnix G.E.H. Lam, Bart de Keizer
Published 2021-04-01

CD47-SIRPα Checkpoint Inhibition Enhances Neutrophil-Mediated Killing of Dinutuximab-Opsonized Neuroblastoma Cells

by Paula Martínez-Sanz, Arjan J. Hoogendijk, Paul J. J. H. Verkuijlen, Karin Schornagel, Robin van Bruggen, Timo K. van den Berg, Godelieve A. M. Tytgat, Katka Franke, Taco W. Kuijpers, Hanke L. Matlung
Published 2021-08-01

Specific and Sensitive Detection of Neuroblastoma mRNA Markers by Multiplex RT-qPCR

by Lieke M. J. van Zogchel, Lily Zappeij-Kannegieter, Ahmad Javadi, Marjolein Lugtigheid, Nina U. Gelineau, Nathalie S. M. Lak, Danny A. Zwijnenburg, Jan Koster, Janine Stutterheim, C. Ellen van der Schoot, Godelieve A. M. Tytgat
Published 2021-01-01

Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

by Justine N. van der Beek, James I. Geller, Ronald R. de Krijger, Norbert Graf, Kathy Pritchard-Jones, Jarno Drost, Arnauld C. Verschuur, Dermot Murphy, Satyajit Ray, Filippo Spreafico, Kristina Dzhuma, Annemieke S. Littooij, Barbara Selle, Godelieve A. M. Tytgat, Marry M. van den Heuvel-Eibrink
Published 2020-07-01

Organoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors

by Camilla Calandrini, Sander R. van Hooff, Irene Paassen, Dilara Ayyildiz, Sepide Derakhshan, M. Emmy M. Dolman, Karin P.S. Langenberg, Marieke van de Ven, Cecilia de Heus, Nalan Liv, Marcel Kool, Ronald R. de Krijger, Godelieve A.M. Tytgat, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Jarno Drost
Published 2021-08-01

G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment

by Taco W Kuijpers, Timo K van den Berg, Paula Martinez Sanz, Dieke J van Rees, Lieke M J van Zogchel, Bart Klein, Panagiota Bouti, Hugo Olsman, Karin Schornagel, Ivana Kok, Ali Sunak, Kira Leeuwenburg, Ilse Timmerman, Miranda P Dierselhuis, Waleed M Kholosy, Jan J Molenaar, Robin van Bruggen, Hanke L Matlung, Godelieve A M Tytgat, Katka Franke
Published 2021-05-01

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

by Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, Emmy Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten Rookmaaker, Marianne Verhaar, Godelieve A. M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al-Saadi, Kathy Pritchard-Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost
Published 2020-03-01