Association of Matrix Metalloproteinase-9 (MMP9) Variants with Primary Angle Closure and Primary Angle Closure Glaucoma.

by Xueli Chen, Yuhong Chen, Janey L Wiggs, Louis R Pasquale, Xinghuai Sun, Bao Jian Fan
Published 2016-01-01

Bupropion use and risk of open-angle glaucoma among enrollees in a large U.S. managed care network.

by Joshua D Stein, Nidhi Talwar, Jae H Kang, Olivia I Okereke, Janey L Wiggs, Louis R Pasquale
Published 2015-01-01

Muir-Torre Syndrome: The Importance of a Detailed Family History

by Christopher K.H. Burris, Maria E. Rodriguez, Meisha L. Raven, Devasis N. Reddy, Yaohui G. Xu, Janey L. Wiggs, Heather D. Potter, Daniel M. Albert
Published 2019-05-01

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

by Sumana R. Chintalapudi, Doaa Maria, Xiang Di Wang, Jessica N. Cooke Bailey, NEIGHBORHOOD consortium, International Glaucoma Genetics consortium, Pirro G. Hysi, Janey L. Wiggs, Robert W. Williams, Monica M. Jablonski
Published 2017-11-01

Habitual coffee consumption and genetic predisposition to obesity: gene-diet interaction analyses in three US prospective studies

by Tiange Wang, Tao Huang, Jae H. Kang, Yan Zheng, Majken K. Jensen, Janey L. Wiggs, Louis R. Pasquale, Charles S. Fuchs, Hannia Campos, Eric B. Rimm, Walter C. Willett, Frank B. Hu, Lu Qi
Published 2017-05-01

The GGLEAM Study: Understanding Glaucoma in the Ohio Amish

by Andrea R. Waksmunski, Yeunjoo E. Song, Tyler G. Kinzy, Reneé A. Laux, Jane Sewell, Denise Fuzzell, Sarada Fuzzell, Sherri Miller, Janey L. Wiggs, Louis R. Pasquale, Jonathan M. Skarie, Jonathan L. Haines, Jessica N. Cooke Bailey
Published 2021-02-01

The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in caucasians with primary open angle glaucoma.

by Janey L Wiggs, Alex W Hewitt, Bao Jian Fan, Dan Yi Wang, Dayse R Figueiredo Sena, Colm O'Brien, Anthony Realini, Jamie E Craig, David P Dimasi, David A Mackey, Jonathan L Haines, Louis R Pasquale
Published 2012-01-01

Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.

by Megan Ulmer Carnes, Yangfan P Liu, R Rand Allingham, Benjamin T Whigham, Shane Havens, Melanie E Garrett, Chunyan Qiao, NEIGHBORHOOD Consortium Investigators, Nicholas Katsanis, Janey L Wiggs, Louis R Pasquale, Allison Ashley-Koch, Edwin C Oh, Michael A Hauser
Published 2014-01-01

Genome-wide linkage scan for primary open angle glaucoma: influences of ancestry and age at diagnosis.

by Kristy R Crooks, R Rand Allingham, Xuejun Qin, Yutao Liu, Jason R Gibson, Cecilia Santiago-Turla, Karen R Larocque-Abramson, Elizabeth Del Bono, Pratap Challa, Leon W Herndon, Stephen Akafo, Janey L Wiggs, Silke Schmidt, Michael A Hauser
Published 2011-01-01

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma.

by Rebecca King, Felix L Struebing, Ying Li, Jiaxing Wang, Allison Ashley Koch, Jessica N Cooke Bailey, Puya Gharahkhani, International Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium, Stuart MacGregor, R Rand Allingham, Michael A Hauser, Janey L Wiggs, Eldon E Geisert
Published 2018-01-01

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium.

by Shefali Setia Verma, Jessica N Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G Linneman, Michael A Hauser, Louis R Pasquale, Peggy L Peissig, Murray H Brilliant, Catherine A McCarty, Jonathan L Haines, Janey L Wiggs, Tamara R Vrabec, Gerard Tromp, Marylyn D Ritchie, eMERGE Network, NEIGHBOR Consortium
Published 2016-09-01

A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts.

by Sara Lindström, Stephanie Loomis, Constance Turman, Hongyan Huang, Jinyan Huang, Hugues Aschard, Andrew T Chan, Hyon Choi, Marilyn Cornelis, Gary Curhan, Immaculata De Vivo, A Heather Eliassen, Charles Fuchs, Michael Gaziano, Susan E Hankinson, Frank Hu, Majken Jensen, Jae H Kang, Christopher Kabrhel, Liming Liang, Louis R Pasquale, Eric Rimm, Meir J Stampfer, Rulla M Tamimi, Shelley S Tworoger, Janey L Wiggs, David J Hunter, Peter Kraft
Published 2017-01-01

Exome-based investigation of the genetic basis of human pigmentary glaucoma

by Carly van der Heide, Wes Goar, Kacie J. Meyer, Wallace L. M. Alward, Erin A. Boese, Nathan C. Sears, Ben R. Roos, Young H. Kwon, Adam P. DeLuca, Owen M. Siggs, Claudia Gonzaga-Jauregui, Val C. Sheffield, Kai Wang, Edwin M. Stone, Robert F. Mullins, Michael G. Anderson, Bao Jian Fan, Robert Ritch, Jamie E. Craig, Janey L. Wiggs, Todd E. Scheetz, John H. Fingert
Published 2021-06-01

Soluble guanylate cyclase α1-deficient mice: a novel murine model for primary open angle glaucoma.

by Emmanuel S Buys, Yu-Chieh Ko, Clemens Alt, Sarah R Hayton, Alexander Jones, Laurel T Tainsh, Ruiyi Ren, Andrea Giani, Maeva Clerté, Emma Abernathy, Robert E T Tainsh, Dong-Jin Oh, Rajeev Malhotra, Pankaj Arora, Nadine de Waard, Binglan Yu, Raphael Turcotte, Daniel Nathan, Marielle Scherrer-Crosbie, Stephanie J Loomis, Jae H Kang, Charles P Lin, Haiyan Gong, Douglas J Rhee, Peter Brouckaert, Janey L Wiggs, Meredith S Gregory, Louis R Pasquale, Kenneth D Bloch, Bruce R Ksander
Published 2013-01-01

Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

by Hannah Currant, Pirro Hysi, Tomas W Fitzgerald, Puya Gharahkhani, Pieter W M Bonnemaijer, Anne Senabouth, Alex W Hewitt, UK Biobank Eye and Vision Consortium, International Glaucoma Genetics Consortium, Denize Atan, Tin Aung, Jason Charng, Hélène Choquet, Jamie Craig, Peng T Khaw, Caroline C W Klaver, Michiaki Kubo, Jue-Sheng Ong, Louis R Pasquale, Charles A Reisman, Maciej Daniszewski, Joseph E Powell, Alice Pébay, Mark J Simcoe, Alberta A H J Thiadens, Cornelia M van Duijn, Seyhan Yazar, Eric Jorgenson, Stuart MacGregor, Chris J Hammond, David A Mackey, Janey L Wiggs, Paul J Foster, Praveen J Patel, Ewan Birney, Anthony P Khawaja
Published 2021-05-01

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.

by Janey L Wiggs, Brian L Yaspan, Michael A Hauser, Jae H Kang, R Rand Allingham, Lana M Olson, Wael Abdrabou, Bao J Fan, Dan Y Wang, Wendy Brodeur, Donald L Budenz, Joseph Caprioli, Andrew Crenshaw, Kristy Crooks, Elizabeth Delbono, Kimberly F Doheny, David S Friedman, Douglas Gaasterland, Terry Gaasterland, Cathy Laurie, Richard K Lee, Paul R Lichter, Stephanie Loomis, Yutao Liu, Felipe A Medeiros, Cathy McCarty, Daniel Mirel, Sayoko E Moroi, David C Musch, Anthony Realini, Frank W Rozsa, Joel S Schuman, Kathleen Scott, Kuldev Singh, Joshua D Stein, Edward H Trager, Paul Vanveldhuisen, Douglas Vollrath, Gadi Wollstein, Sachiko Yoneyama, Kang Zhang, Robert N Weinreb, Jason Ernst, Manolis Kellis, Tomohiro Masuda, Don Zack, Julia E Richards, Margaret Pericak-Vance, Louis R Pasquale, Jonathan L Haines
Published 2012-01-01

Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

by Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study - GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, Wellcome Trust Case Control Consortium 2 (WTCCC2), NEIGHBORHOOD consortium, André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor
Published 2019-01-01

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

by Adriana I. Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Henriët Springelkamp, Gabriel Cuellar-Partida, Puya Gharahkhani, Jessica N. Cooke Bailey, Colin E. Willoughby, Xiaohui Li, Seyhan Yazar, Abhishek Nag, Anthony P. Khawaja, Ozren Polašek, David Siscovick, Paul Mitchell, Yih Chung Tham, Jonathan L. Haines, Lisa S. Kearns, Caroline Hayward, Yuan Shi, Elisabeth M. van Leeuwen, Kent D. Taylor, Blue Mountains Eye Study—GWAS group, Pieter Bonnemaijer, Jerome I. Rotter, Nicholas G. Martin, Tanja Zeller, Richard A. Mills, Emmanuelle Souzeau, Sandra E. Staffieri, Jost B. Jonas, Irene Schmidtmann, Thibaud Boutin, Jae H. Kang, Sionne E. M. Lucas, Tien Yin Wong, Manfred E. Beutel, James F. Wilson, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), André G. Uitterlinden, Eranga N. Vithana, Paul J. Foster, Pirro G. Hysi, Alex W. Hewitt, Chiea Chuen Khor, Louis R. Pasquale, Grant W. Montgomery, Caroline C. W. Klaver, Tin Aung, Norbert Pfeiffer, David A. Mackey, Christopher J. Hammond, Ching-Yu Cheng, Jamie E. Craig, Yaron S. Rabinowitz, Janey L. Wiggs, Kathryn P. Burdon, Cornelia M. van Duijn, Stuart MacGregor
Published 2018-05-01

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

by Puya Gharahkhani, Eric Jorgenson, Pirro Hysi, Anthony P. Khawaja, Sarah Pendergrass, Xikun Han, Jue Sheng Ong, Alex W. Hewitt, Ayellet V. Segrè, John M. Rouhana, Andrew R. Hamel, Robert P. Igo, Helene Choquet, Ayub Qassim, Navya S. Josyula, Jessica N. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana Iglesias, Owen M. Siggs, Terri L. Young, Veronique Vitart, Alberta A. H. J. Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B. Melles, K. Saidas Nair, Robert Luben, Mark Simcoe, Nishani Amersinghe, Angela J. Cree, Rene Hohn, Alicia Poplawski, Li Jia Chen, Shi-Song Rong, Tin Aung, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Gen Tamiya, Yukihiro Shiga, Masayuki Yamamoto, Toru Nakazawa, Hannah Currant, Ewan Birney, Xin Wang, Adam Auton, Michelle K. Lupton, Nicholas G. Martin, Adeyinka Ashaye, Olusola Olawoye, Susan E. Williams, Stephen Akafo, Michele Ramsay, Kazuki Hashimoto, Yoichiro Kamatani, Masato Akiyama, Yukihide Momozawa, Paul J. Foster, Peng T. Khaw, James E. Morgan, Nicholas G. Strouthidis, Peter Kraft, Jae H. Kang, Chi Pui Pang, Francesca Pasutto, Paul Mitchell, Andrew J. Lotery, Aarno Palotie, Cornelia van Duijn, Jonathan L. Haines, Chris Hammond, Louis R. Pasquale, Caroline C. W. Klaver, Michael Hauser, Chiea Chuen Khor, David A. Mackey, Michiaki Kubo, Ching-Yu Cheng, Jamie E. Craig, Stuart MacGregor, Janey L. Wiggs
Published 2021-02-01