Challenges in studying geographic atrophy (GA) age-related macular degeneration: the potential of a new mouse model with GA-like features

by J Arjuna Ratnayaka, Andrew J Lotery
Published 2020-01-01

Impaired Cargo Clearance in the Retinal Pigment Epithelium (RPE) Underlies Irreversible Blinding Diseases

by Eloise Keeling, Andrew J. Lotery, David A. Tumbarello, J. Arjuna Ratnayaka
Published 2018-02-01

The complexities underlying age-related macular degeneration: could amyloid beta play an important role?

by Savannah A Lynn, Eloise Keeling, Rosie Munday, Gagandeep Gabha, Helen Griffiths, Andrew J Lotery, J Arjuna Ratnayaka
Published 2017-01-01

Multimodal Imaging in the Management of Choroidal Neovascularization Secondary to Central Serous Chorioretinopathy

by Ahmed M. Hagag, Shruti Chandra, Hagar Khalid, Ali Lamin, Pearse A. Keane, Andrew J. Lotery, Sobha Sivaprasad
Published 2020-06-01

Treatment Satisfaction and Well-Being in Patients with Myopic Choroidal Neovascularization Treated with Ranibizumab in the REPAIR Study.

by Winfried M Amoaku, Richard P Gale, Andrew J Lotery, Geeta Menon, Sobha Sivaprasad, Jennifer Petrillo, Jennifer Quinn
Published 2015-01-01

An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy

by Eloise Keeling, Annabelle J. Culling, David A. Johnston, David S. Chatelet, Anton Page, David A. Tumbarello, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2020-09-01

A novel, wearable, electronic visual aid to assist those with reduced peripheral vision.

by Ffion E Brown, Janice Sutton, Ho M Yuen, Dylan Green, Spencer Van Dorn, Terry Braun, Angela J Cree, Stephen R Russell, Andrew J Lotery
Published 2019-01-01

Characterization of the Frmd7 Knock-Out Mice Generated by the EUCOMM/COMP Repository as a Model for Idiopathic Infantile Nystagmus (IIN)

by Ahmed Salman, Samuel B. Hutton, Tutte Newall, Jennifer A. Scott, Helen L. Griffiths, Helena Lee, Diego Gomez-Nicola, Andrew J. Lotery, Jay E. Self
Published 2020-09-01

3D-Reconstructed Retinal Pigment Epithelial Cells Provide Insights into the Anatomy of the Outer Retina

by Eloise Keeling, David S. Chatelet, Nicole Y. T. Tan, Farihah Khan, Rhys Richards, Thibana Thisainathan, Patricia Goggin, Anton Page, David A. Tumbarello, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2020-11-01

A convenient protocol for establishing a human cell culture model of the outer retina. [version 1; referees: 2 approved]

by Savannah A. Lynn, Eloise Keeling, Jennifer M. Dewing, David A. Johnston, Anton Page, Angela J. Cree, David A. Tumbarello, Tracey A. Newman, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2018-07-01

AAV2/8 Anti-angiogenic Gene Therapy Using Single-Chain Antibodies Inhibits Murine Choroidal Neovascularization

by Chris P. Hughes, Neil M.J. O’Flynn, Maureen Gatherer, Michelle E. McClements, Jennifer A. Scott, Robert E. MacLaren, Srinivas Goverdhan, Martin J. Glennie, Andrew J. Lotery
Published 2019-06-01

A randomised controlled trial to assess the clinical effectiveness and cost-effectiveness of alternative treatments to Inhibit VEGF in Age-related choroidal Neovascularisation (IVA...

by Usha Chakravarthy, Simon P Harding, Chris A Rogers, Susan Downes, Andrew J Lotery, Helen A Dakin, Lucy Culliford, Lauren J Scott, Rachel L Nash, Jodi Taylor, Alyson Muldrew, Jayashree Sahni, Sarah Wordsworth, James Raftery, Tunde Peto, Barnaby C Reeves
Published 2015-10-01

Oligomeric Aβ_1-42 Induces an AMD-Like Phenotype and Accumulates in Lysosomes to Impair RPE Function

by Savannah A. Lynn, David A. Johnston, Jenny A. Scott, Rosie Munday, Roshni S. Desai, Eloise Keeling, Ruaridh Weaterton, Alexander Simpson, Dillon Davis, Thomas Freeman, David S. Chatelet, Anton Page, Angela J. Cree, Helena Lee, Tracey A. Newman, Andrew J. Lotery, J. Arjuna Ratnayaka
Published 2021-02-01

A small gene sequencing panel realises a high diagnostic rate in patients with congenital nystagmus following basic phenotyping

by Luke O’Gorman, Chelsea S. Norman, Luke Michaels, Tutte Newall, Andrew H. Crosby, Christopher Mattocks, Angela J. Cree, Andrew J. Lotery, Emma L. Baple, J. Arjuna Ratnayaka, Diana Baralle, Helena Lee, Daniel Osborne, Fatima Shawkat, Jane Gibson, Sarah Ennis, Jay E. Self
Published 2019-09-01

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

by Puya Gharahkhani, Eric Jorgenson, Pirro Hysi, Anthony P. Khawaja, Sarah Pendergrass, Xikun Han, Jue Sheng Ong, Alex W. Hewitt, Ayellet V. Segrè, John M. Rouhana, Andrew R. Hamel, Robert P. Igo, Helene Choquet, Ayub Qassim, Navya S. Josyula, Jessica N. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana Iglesias, Owen M. Siggs, Terri L. Young, Veronique Vitart, Alberta A. H. J. Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B. Melles, K. Saidas Nair, Robert Luben, Mark Simcoe, Nishani Amersinghe, Angela J. Cree, Rene Hohn, Alicia Poplawski, Li Jia Chen, Shi-Song Rong, Tin Aung, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Gen Tamiya, Yukihiro Shiga, Masayuki Yamamoto, Toru Nakazawa, Hannah Currant, Ewan Birney, Xin Wang, Adam Auton, Michelle K. Lupton, Nicholas G. Martin, Adeyinka Ashaye, Olusola Olawoye, Susan E. Williams, Stephen Akafo, Michele Ramsay, Kazuki Hashimoto, Yoichiro Kamatani, Masato Akiyama, Yukihide Momozawa, Paul J. Foster, Peng T. Khaw, James E. Morgan, Nicholas G. Strouthidis, Peter Kraft, Jae H. Kang, Chi Pui Pang, Francesca Pasutto, Paul Mitchell, Andrew J. Lotery, Aarno Palotie, Cornelia van Duijn, Jonathan L. Haines, Chris Hammond, Louis R. Pasquale, Caroline C. W. Klaver, Michael Hauser, Chiea Chuen Khor, David A. Mackey, Michiaki Kubo, Ching-Yu Cheng, Jamie E. Craig, Stuart MacGregor, Janey L. Wiggs
Published 2021-02-01