Epigenetic Reprogramming of Lineage-Committed Human Mammary Epithelial Cells Requires DNMT3A and Loss of DOT1L

by Jerrica L. Breindel, Adam Skibinski, Maja Sedic, Ania Wronski-Campos, Wenhui Zhou, Patricia J. Keller, Joslyn Mills, James Bradner, Tamer Onder, Charlotte Kuperwasser
Published 2017-09-01

PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer

by Jennifer M. Spangle, Koen M. Dreijerink, Anna C. Groner, Hailing Cheng, Carolynn E. Ohlson, Jaime Reyes, Charles Y. Lin, James Bradner, Jean J. Zhao, Thomas M. Roberts, Myles Brown
Published 2016-06-01

A Novel Bromodomain Inhibitor Reverses HIV-1 Latency through Specific Binding with BRD4 to Promote Tat and P-TEFb Association

by Huachao Huang, Shuai Liu, Maxime Jean, Sydney Simpson, He Huang, Mark Merkley, Tsuyoshi Hayashi, Weili Kong, Irene Rodríguez-Sánchez, Xiaofeng Zhang, Hailemichael O. Yosief, Hongyu Miao, Jianwen Que, James J. Kobie, James Bradner, Netty G. Santoso, Wei Zhang, Jian Zhu
Published 2017-06-01