Heparan Sulfate Proteoglycans Biosynthesis and Post Synthesis Mechanisms Combine Few Enzymes and Few Core Proteins to Generate Extensive Structural and Functional Diversity

by Thibault Annaval, Rebekka Wild, Yoann Crétinon, Rabia Sadir, Romain R. Vivès, Hugues Lortat-Jacob
Published 2020-09-01

Hijacking of the pleiotropic cytokine interferon-γ by the type III secretion system of Yersinia pestis.

by Claire Gendrin, Stéphane Sarrazin, David Bonnaffé, Jean-Michel Jault, Hugues Lortat-Jacob, Andréa Dessen
Published 2010-01-01

Axonal chemokine-like Orion induces astrocyte infiltration and engulfment during mushroom body neuronal remodeling

by Ana Boulanger, Camille Thinat, Stephan Züchner, Lee G. Fradkin, Hugues Lortat-Jacob, Jean-Maurice Dura
Published 2021-03-01

The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4.

by Cédric Laguri, Rabia Sadir, Patricia Rueda, Françoise Baleux, Pierre Gans, Fernando Arenzana-Seisdedos, Hugues Lortat-Jacob
Published 2007-01-01

A New C-Xyloside induces modifications of GAG expression, structure and functional properties.

by Emilie Vassal-Stermann, Albert Duranton, Annie F Black, Gayane Azadiguian, Julien Demaude, Hugues Lortat-Jacob, Lionel Breton, Romain R Vivès
Published 2012-01-01

Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains

by Yoan R. Monneau, Lingjie Luo, Nehru Viji Sankaranarayanan, Balaji Nagarajan, Romain R. Vivès, Françoise Baleux, Umesh R. Desai, Fernando Arenzana-Seidedos, Hugues Lortat-Jacob
Published 2017-01-01

A Versatile Electronic Tongue Based on Surface Plasmon Resonance Imaging and Cross-Reactive Sensor Arrays—A Mini-Review

by Laurie-Amandine Garçon, Maria Genua, Yanjie Hou, Arnaud Buhot, Roberto Calemczuk, Thierry Livache, Martial Billon, Christine Le Narvor, David Bonnaffé, Hugues Lortat-Jacob, Yanxia Hou
Published 2017-05-01

A Cinnamon-Derived Procyanidin Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impedin...

by Bridgette Janine Connell, Sui-Yuan Chang, Ekambaranellore Prakash, Rahima Yousfi, Viswaraman Mohan, Wilfried Posch, Doris Wilflingseder, Christiane Moog, Eiichi N Kodama, Pascal Clayette, Hugues Lortat-Jacob
Published 2016-01-01

The signal peptide of Staphylococcus aureus panton valentine leukocidin LukS component mediates increased adhesion to heparan sulfates.

by Anne Tristan, Yvonne Benito, Roland Montserret, Sandrine Boisset, Eric Dusserre, Francois Penin, Florence Ruggiero, Jerome Etienne, Hugues Lortat-Jacob, Gerard Lina, M Gabriela Bowden, François Vandenesch
Published 2009-01-01

Cytokines and growth factors cross-link heparan sulfate

by Elisa Migliorini, Dhruv Thakar, Jens Kühnle, Rabia Sadir, Douglas P. Dyer, Yong Li, Changye Sun, Brian F. Volkman, Tracy M. Handel, Liliane Coche-Guerente, David G. Fernig, Hugues Lortat-Jacob, Ralf P. Richter
Published 2015-01-01

The cell adhesion molecule "CAR" and sialic acid on human erythrocytes influence adenovirus in vivo biodistribution.

by Elena Seiradake, Daniel Henaff, Harald Wodrich, Olivier Billet, Matthieu Perreau, Claire Hippert, Franck Mennechet, Guy Schoehn, Hugues Lortat-Jacob, Hanna Dreja, Sandy Ibanes, Vasiliki Kalatzis, Jennifer P Wang, Robert W Finberg, Stephen Cusack, Eric J Kremer
Published 2009-01-01

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins.

by Patricia Rueda, Karl Balabanian, Bernard Lagane, Isabelle Staropoli, Ken Chow, Angelique Levoye, Cedric Laguri, Rabia Sadir, Thierry Delaunay, Elena Izquierdo, Jose Luis Pablos, Elena Lendinez, Antonio Caruz, Diego Franco, Françoise Baleux, Hugues Lortat-Jacob, Fernando Arenzana-Seisdedos
Published 2008-07-01

CCR5 structural plasticity shapes HIV-1 phenotypic properties.

by Philippe Colin, Zhicheng Zhou, Isabelle Staropoli, Javier Garcia-Perez, Romain Gasser, Marie Armani-Tourret, Yann Benureau, Nuria Gonzalez, Jun Jin, Bridgette J Connell, Stéphanie Raymond, Pierre Delobel, Jacques Izopet, Hugues Lortat-Jacob, Jose Alcami, Fernando Arenzana-Seisdedos, Anne Brelot, Bernard Lagane
Published 2018-12-01