The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4.

by Cédric Laguri, Rabia Sadir, Patricia Rueda, Françoise Baleux, Pierre Gans, Fernando Arenzana-Seisdedos, Hugues Lortat-Jacob
Published 2007-01-01

Solution structure of CXCL13 and heparan sulfate binding show that GAG binding site and cellular signalling rely on distinct domains

by Yoan R. Monneau, Lingjie Luo, Nehru Viji Sankaranarayanan, Balaji Nagarajan, Romain R. Vivès, Françoise Baleux, Umesh R. Desai, Fernando Arenzana-Seidedos, Hugues Lortat-Jacob
Published 2017-01-01

CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension.

by Alexandre Denoyer, David Godefroy, Isabelle Célérier, Julie Frugier, Julie Degardin, Jeffrey K Harrison, Francoise Brignole-Baudouin, Serge Picaud, Francoise Baleux, José A Sahel, William Rostène, Christophe Baudouin
Published 2012-01-01

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins.

by Patricia Rueda, Karl Balabanian, Bernard Lagane, Isabelle Staropoli, Ken Chow, Angelique Levoye, Cedric Laguri, Rabia Sadir, Thierry Delaunay, Elena Izquierdo, Jose Luis Pablos, Elena Lendinez, Antonio Caruz, Diego Franco, Françoise Baleux, Hugues Lortat-Jacob, Fernando Arenzana-Seisdedos
Published 2008-07-01