Host urine immunological biomarkers as potential candidates for the diagnosis of tuberculosis

by Osagie A. Eribo, Monkoe S. Leqheka, Stephanus T. Malherbe, Shirley McAnda, Kim Stanley, Gian D. van der Spuy, Gerhard Walzl, Novel N. Chegou
Published 2020-10-01

Performance and immune characteristics of bronchoalveolar lavage by research bronchoscopy in pulmonary tuberculosis and other lung diseases in the Western Cape, South Africa

by Carly Young, Petri Ahlers, Andriette M. Hiemstra, Andre G. Loxton, Andrea Gutschmidt, Stephanus T. Malherbe, Gerhard Walzl, Nelita Du Plessis, the SU-IRG consortium
Published 2019-06-01

The Functional Response of B Cells to Antigenic Stimulation: A Preliminary Report of Latent Tuberculosis.

by Willem J du Plessis, Léanie Kleynhans, Nelita du Plessis, Kim Stanley, Stephanus T Malherbe, Elizna Maasdorp, Katharina Ronacher, Novel N Chegou, Gerhard Walzl, Andre G Loxton
Published 2016-01-01

Investigating Non-sterilizing Cure in TB Patients at the End of Successful Anti-TB Therapy

by Caroline G. G. Beltran, Caroline G. G. Beltran, Tiaan Heunis, Tiaan Heunis, Tiaan Heunis, James Gallant, James Gallant, James Gallant, Rouxjeane Venter, Rouxjeane Venter, Nelita du Plessis, Nelita du Plessis, Andre G. Loxton, Andre G. Loxton, Matthias Trost, Jill Winter, Stephanus T. Malherbe, Stephanus T. Malherbe, Bavesh D. Kana, Bavesh D. Kana, Bavesh D. Kana, Gerhard Walzl, Gerhard Walzl
Published 2020-08-01

Establishment of a Patient-Derived, Magnetic Levitation-Based, Three-Dimensional Spheroid Granuloma Model for Human Tuberculosis

by Leigh A. Kotze, Caroline G. G. Beltran, Dirk Lang, Andre G. Loxton, Susan Cooper, Maynard Meiring, Coenraad F. N. Koegelenberg, Brian W. Allwood, Stephanus T. Malherbe, Andriette M. Hiemstra, Brigitte Glanzmann, Craig Kinnear, Gerhard Walzl, Nelita du Plessis
Published 2021-08-01

The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment

by Trust Odia, Trust Odia, Trust Odia, Trust Odia, Trust Odia, Stephanus T. Malherbe, Stephanus T. Malherbe, Stephanus T. Malherbe, Stuart Meier, Stuart Meier, Stuart Meier, Stuart Meier, Stuart Meier, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Léanie Kleynhans, Léanie Kleynhans, Léanie Kleynhans, Nelita du Plessis, Nelita du Plessis, Nelita du Plessis, Andre G. Loxton, Andre G. Loxton, Andre G. Loxton, Daniel E. Zak, Ethan Thompson, Fergal J. Duffy, Fergal J. Duffy, Helena Kuivaniemi, Helena Kuivaniemi, Helena Kuivaniemi, Katharina Ronacher, Katharina Ronacher, Katharina Ronacher, Katharina Ronacher, Jill Winter, Gerhard Walzl, Gerhard Walzl, Gerhard Walzl, Gerhard Walzl, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, the Catalysis TB-Biomarker Consortium, André G. Loxton, Annare Ellman, Bronwyn Smith, Caroline G. G. Beltran, Clifton E. Barry, David Alland, Friedrich Thienemann, Gerard Tromp, Gerhard Walzl, James M. Warwick, Jill Winter, Katharina Ronacher, Kim Stanley, Ilse Kant, Lani Thiart, Lance A. Lucas, Laura E. Via, Lori E. Dodd, Magdalena Kriel, Nelita Plessis Du, Patrick Dupont, Ray Y. Chen, Robert J. Wilkinson, Shubhada Shenai, Stephanie Griffith-Richards, Stephanus T. Malherbe
Published 2021-02-01

Higher SARS-CoV-2 seroprevalence in workers with lower socioeconomic status in Cape Town, South Africa.

by Jane Alexandra Shaw, Maynard Meiring, Tracy Cummins, Novel N Chegou, Conita Claassen, Nelita Du Plessis, Marika Flinn, Andriette Hiemstra, Léanie Kleynhans, Vinzeigh Leukes, Andre G Loxton, Candice MacDonald, Nosipho Mtala, Helmuth Reuter, Donald Simon, Kim Stanley, Gerard Tromp, Wolfgang Preiser, Stephanus T Malherbe, Gerhard Walzl
Published 2021-01-01

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

by Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl, James M. Warwick, the Catalysis Biomarker Consortium
Published 2018-06-01

Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease

by Hygon Mutavhatsindi, Gian D. van der Spuy, Stephanus T. Malherbe, Jayne S. Sutherland, Annemieke Geluk, Harriet Mayanja-Kizza, Amelia C. Crampin, Desta Kassa, Rawleigh Howe, Adane Mihret, Jacob A. Sheehama, Emmanuel Nepolo, Gunar Günther, Hazel M. Dockrell, Paul L. A. M. Corstjens, Kim Stanley, Gerhard Walzl, Novel N. Chegou, the AE-TBC ScreenTB Consortia
Published 2021-02-01

Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response

by Stephanus T. Malherbe, Ray Y. Chen, Patrick Dupont, Ilse Kant, Magdalena Kriel, André G. Loxton, Bronwyn Smith, Caroline G. G. Beltran, Susan van Zyl, Shirely McAnda, Charmaine Abrahams, Elizna Maasdorp, Alex Doruyter, Laura E. Via, Clifton E. Barry, David Alland, Stephanie Griffith- Richards, Annare Ellman, Thomas Peppard, John Belisle, Gerard Tromp, Katharina Ronacher, James M. Warwick, Jill Winter, Gerhard Walzl
Published 2020-02-01

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial [version 1; referees: 3 approved]

by Ray Y. Chen, Laura E. Via, Lori E. Dodd, Gerhard Walzl, Stephanus T. Malherbe, André G. Loxton, Rodney Dawson, Robert J. Wilkinson, Friedrich Thienemann, Michele Tameris, Mark Hatherill, Andreas H. Diacon, Xin Liu, Jin Xing, Xiaowei Jin, Zhenya Ma, Shouguo Pan, Guolong Zhang, Qian Gao, Qi Jiang, Hong Zhu, Lili Liang, Hongfei Duan, Taeksun Song, David Alland, Michael Tartakovsky, Alex Rosenthal, Christopher Whalen, Michael Duvenhage, Ying Cai, Lisa C. Goldfeder, Kriti Arora, Bronwyn Smith, Jill Winter, Clifton E. Barry III, Predict TB Study Group
Published 2017-11-01

Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study

by Simon C Mendelsohn, MBChB, Andrew Fiore-Gartland, PhD, Adam Penn-Nicholson, PhD, Humphrey Mulenga, MPH, Stanley Kimbung Mbandi, PhD, Bhavesh Borate, MS, Katie Hadley, PhD, Chris Hikuam, PhD, Munyaradzi Musvosvi, PhD, Nicole Bilek, PhD, Mzwandile Erasmus, BSc, Lungisa Jaxa, BTech, Rodney Raphela, BSc, Onke Nombida, GT, Masooda Kaskar, MBChB, Tom Sumner, PhD, Richard G White, PhD, Craig Innes, MBChB, William Brumskine, MBChB, Andriëtte Hiemstra, MBChB, Stephanus T Malherbe, MBChB, Razia Hassan-Moosa, MPH, Michèle Tameris, MBChB, Gerhard Walzl, MBChB, Kogieleum Naidoo, PhD, Gavin Churchyard, PhD, Thomas J Scriba, DPhil, Mark Hatherill, ProfMD, Charmaine Abrahams, Hadn Africa, Petri Ahlers, Denis Arendsen, Tebogo Badimo, Kagiso Baepanye, Kesenogile Edna Baepanye, Bianca Bande, Nomfuneko Cynthia Batyi, Roslyn Beukes, Laudicia Tshenolo Bontsi, Obakeng Peter Booi, Mari Cathrin Botha, Samentra Braaf, Sivuyile Buhlungu, Alida Carstens, Kgomotso Violet Chauke, Thilagavathy Chinappa, Eva Chung, Michelle Chung, Ken Clarke, Yolundi Cloete, Lorraine Coetzee, Marelize Collignon, Alessandro Companie, Cara-mia Corris, Mooketsi Theophillius Cwaile, Thobelani Cwele, Ilse Davids, Isabella Johanna Davies, Emilia De Klerk, Marwou de Kock, Audrey Lebohang Dhlamini, Bongani Diamond, Maria Didloff, Celaphiwe Dlamini, Palesa Dolo, Candice Eyre, Tebogo Feni, Juanita Ferreira, Christal Ferus, Michelle Fisher, Marika Flinn, Bernadine Fransman, Welseh Phindile Galane, Hennie Geldenhuys, Diann Gempies, Thelma Goliath, Dhineshree Govender, Yolande Gregg, Goodness Gumede, Zanele Gwamada, Senzo Halti, Rieyaat Hassiem, Roxane Herling, Yulandi Herselman, Ellis Hughes, Henry Issel, Blanchard Mbay Iyemosolo, Zandile Jali, Bonita Janse Van Rensburg, Ruwiyda Jansen, James Michael Jeleni, Olebogeng Jonkane, Fabio Julies, Fazlin Kafaar, Christian Mabika Kasongo, Christian Mabika Kasongo, Sophie Keffers, Boitumelo Sophy Kekana, Sebaetseng Jeanette Kekana, Xoliswa Kelepu, Lungile Khanyile, Gomotsegang Virginia Khobedi, Gloria Khomba, Lucky Sipho Khoza, Marietjie King, Gloria Keitumetse Kolobe, Sandra Kruger, Jaftha Kruger, Ndlela Israel Kunene, Sunelza Lakay, Aneesa Lakhi, Nondumiso Langa, Hildah Ledwaba, Lerato Julia Lekagane, Sheiley Christina Lekotloane, Thelma Leopeng, Ilze Jeanette Louw, Angelique Kany Kany Luabeya, Sarah Teboso Lusale, Perfect Tiisetso Maatjie, Immaculate Mabasa, Tshegofatso Dorah Mabe, Kamogelo Fortunate Mabena, Nkosinathi Charles Mabuza, Simbarashe Mabwe, Johanna Thapelo Madikwe, Octavia Mahkosazana Madikwe, Rapontwana Letlhogonolo Maebana, Malobisa Sylvester Magwasha, Molly Majola, Mantai Makhetha, Lebohang Makhethe, Vernon Malay, Vutlhari-I-Vunhenha Fairlord Manzini, Jabu Maphanga, Nonhle Maphanga, Juanita Market, Isholedi Samuel Maroele, Omphile Petunia Masibi, July Rocky Mathabanzini, Tendamudzimu Ivan Mathode, Ellen Ditaba Matsane, Lungile Mbata, Lungile Mbata, Faheema Meyer, Nyasha Karen Mhandire, Thembisiwe Miga, Nosisa Charity Thandeka Mkhize, Caroline Mkhokho, Neo Hilda Mkwalase, Nondzakazi Mnqonywa, Karabo Moche, Brenda Matshidiso Modisaotsile, Patricia Pakiso Mokgetsengoane, Selemeng Matseliso Carol Mokone, Kegomoditswe Magdeline Molatlhegi, Thuso Andrew Molefe, Joseph Panie Moloko, Kabelo Molosi, Motlatsi Evelyn Molotsi, Tebogo Edwin Montwedi, Boikanyo Dinah Monyemangene, Hellen Mokopi Mooketsi, Miriam Moses, Boitumelo Mosito, Tshplpfelo Mapula Mosito, Ireen Lesebang Mosweu, Primrose Mothaga, Banyana Olga Motlagomang, Angelique Mouton, Onesisa Mpofu, Funeka Nomvula Mthembu, Mpho Mtlali, Nhlamulo Ndlovu, Nompumelelo Ngcobo, Julia Noble, Bantubonke Bertrum Ntamo, Gloria Ntanjana, Tedrius Ntshauba, Fajwa Opperman, Nesri Padayatchi, Thandiwe Papalagae, Christel Petersen, Themba Phakathi, Mapule Ozma Phatshwane, Patiswa Plaatjie, Abe Pretorius, Victor Kgothatso Rameetse, Dirhona Ramjit, Frances Ratangee, Maigan Ratangee, Pearl Nomsa Sanyaka, Alicia Sato, Elisma Schoeman, Constance Schreuder, Letlhogonolo Seabela, Kelebogile Magdeline Segaetsho, Ni Ni Sein, Raesibe Agnes Pearl Selepe, Melissa Neo Senne, Melissa Neo Senne, Alison September, Cashwin September, Moeti Serake, Justin Shenje, Thandiwe Shezi, Sifiso Cornelius Shezi, Phindile Sing, Chandrapharbha Singh, Zona Sithetho, Dorothy Solomons, Kim Stanley, Marcia Steyn, Bongiwe Stofile, Sonia Stryers, Liticia Swanepoel, Anne Swarts, Mando Mmakhora Thaba, Lethabo Collen Theko, Philile Thembela, Mugwena Thompo, Asma Toefy, Khayalethu Toto, Dimakatso Sylvia Tsagae, Ayanda Tsamane, Vincent Tshikovhi, Lebogang Isaac Tswaile, Petrus Tyambetyu, Susanne Tönsing, Habibullah Valley, Linda van der Merwe, Elma van Rooyen, Ashley Veldsman, Helen Veldtsman, Kelvin Vollenhoven, Londiwe Zaca, Elaine Zimri, Mbali Zulu
Published 2021-06-01