The location and trafficking routes of the neuronal retromer and its role in amyloid precursor protein transport

by Akhil Bhalla, Christopher P. Vetanovetz, Etienne Morel, Zeina Chamoun, Gilbert Di Paolo, Scott A. Small
Published 2012-07-01

Phospholipase D functional ablation has a protective effect in an Alzheimer’s disease Caenorhabditis elegans model

by Francisca Vaz Bravo, Jorge Da Silva, Robin Barry Chan, Gilbert Di Paolo, Andreia Teixeira-Castro, Tiago Gil Oliveira
Published 2018-02-01

Regulation of mammalian autophagy by class II and III PI 3-kinases through PI3P synthesis.

by Kelly Devereaux, Claudia Dall'Armi, Abel Alcazar-Roman, Yuta Ogasawara, Xiang Zhou, Fan Wang, Akitsugu Yamamoto, Pietro De Camilli, Gilbert Di Paolo
Published 2013-01-01

Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization[S]

by Akua N. Roach, Ziqing Wang, Ping Wu, Feng Zhang, Robin B. Chan, Yoshiya Yonekubo, Gilbert Di Paolo, Alemayehu A. Gorfe, Guangwei Du
Published 2012-12-01

Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism

by Catherine Marquer, Huasong Tian, Julie Yi, Jayson Bastien, Claudia Dall'Armi, YoungJoo Yang-Klingler, Bowen Zhou, Robin Barry Chan, Gilbert Di Paolo
Published 2016-06-01

Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures

by André M. Miranda, Zofia M. Lasiecka, Yimeng Xu, Jessi Neufeld, Sanjid Shahriar, Sabrina Simoes, Robin B. Chan, Tiago Gil Oliveira, Scott A. Small, Gilbert Di Paolo
Published 2018-01-01

Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.

by Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Jeremy S Dittman, William J Rice, Robin B Chan, Gilbert Di Paolo, Christopher T Beh, Anant K Menon
Published 2018-05-01

Deficiencies of the lipid-signaling enzymes phospholipase D1 and D2 alter cytoskeletal organization, macrophage phagocytosis, and cytokine-stimulated neutrophil recruitment.

by Wahida H Ali, Qin Chen, Kathleen E Delgiorno, Wenjuan Su, Jason C Hall, Tsunaki Hongu, Huasong Tian, Yasunori Kanaho, Gilbert Di Paolo, Howard C Crawford, Michael A Frohman
Published 2013-01-01

Elevated GM3 plasma concentration in idiopathic Parkinson's disease: A lipidomic analysis.

by Robin B Chan, Adler J Perotte, Bowen Zhou, Christopher Liong, Evan J Shorr, Karen S Marder, Un J Kang, Cheryl H Waters, Oren A Levy, Yimeng Xu, Hong Bin Shim, Itsik Pe'er, Gilbert Di Paolo, Roy N Alcalay
Published 2017-01-01

HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels

by Petter Holland, Helene Knævelsrud, Kristiane Søreng, Benan J. Mathai, Alf Håkon Lystad, Serhiy Pankiv, Gunnveig T. Bjørndal, Sebastian W. Schultz, Viola H. Lobert, Robin B. Chan, Bowen Zhou, Knut Liestøl, Sven R. Carlsson, Thomas J. Melia, Gilbert Di Paolo, Anne Simonsen
Published 2016-12-01

Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning

by Luísa Santa-Marinha, Isabel Castanho, Rita Ribeiro Silva, Francisca Vaz Bravo, André Miguel Miranda, Torcato Meira, Rafaela Morais-Ribeiro, Fernanda Marques, Yimeng Xu, Kimberly Point du Jour, Markus Wenk, Robin Barry Chan, Gilbert Di Paolo, Vítor Pinto, Tiago Gil Oliveira
Published 2020-03-01

Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms

by Emma Mitchell, Shifra L. Klein, Kimon V. Argyropoulos, Ali Sharma, Robin B. Chan, Judit Gal Toth, Luendreo Barboza, Charlotte Bavley, Analia Bortolozzi, Qiuying Chen, Bingfang Liu, Joanne Ingenito, Willie Mark, Jarrod Dudakov, Steven Gross, Gilbert Di Paolo, Francesc Artigas, Marcel van den Brink, Miklos Toth
Published 2016-05-01

Gene-wise association of variants in four lysosomal storage disorder genes in neuropathologically confirmed Lewy body disease.

by Lorraine N Clark, Robin Chan, Rong Cheng, Xinmin Liu, Naeun Park, Nancy Parmalee, Sergey Kisselev, Etty Cortes, Paola A Torres, Gregory M Pastores, Jean P Vonsattel, Roy Alcalay, Karen Marder, Lawrence L Honig, Stanley Fahn, Richard Mayeux, Michael Shelanski, Gilbert Di Paolo, Joseph H Lee
Published 2015-01-01

Mutations in the cholesterol transporter gene ABCA5 are associated with excessive hair overgrowth.

by Gina M DeStefano, Mazen Kurban, Kwame Anyane-Yeboa, Claudia Dall'Armi, Gilbert Di Paolo, Heather Feenstra, Nanette Silverberg, Luis Rohena, Larissa D López-Cepeda, Vaidehi Jobanputra, Katherine A Fantauzzo, Maija Kiuru, Marija Tadin-Strapps, Antonio Sobrino, Anna Vitebsky, Dorothy Warburton, Brynn Levy, Julio C Salas-Alanis, Angela M Christiano
Published 2014-01-01

Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points

by Samuel S. Pappas, Juan Bonifacino, Adrian Danek, William T. Dauer, Mithu De, Lucia De Franceschi, Gilbert DiPaolo, Robert Fuller, Volker Haucke, Andreas Hermann, Benoit Kornmann, Bernhard Landwehrmeyer, Johannes Levin, Aaron M. Neiman, Dobrila D. Rudnicki, Ody Sibon, Antonio Velayos-Baeza, Jan J. Vonk, Ruth H. Walker, Lois S. Weisman, Roger L. Albin
Published 2017-02-01

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region

by Kai Schlepckow, Kathryn M Monroe, Gernot Kleinberger, Ludovico Cantuti‐Castelvetri, Samira Parhizkar, Dan Xia, Michael Willem, Georg Werner, Nadine Pettkus, Bettina Brunner, Alice Sülzen, Brigitte Nuscher, Heike Hampel, Xianyuan Xiang, Regina Feederle, Sabina Tahirovic, Joshua I Park, Rachel Prorok, Cathal Mahon, Chun‐Chi Liang, Ju Shi, Do Jin Kim, Hanna Sabelström, Fen Huang, Gilbert Di Paolo, Mikael Simons, Joseph W Lewcock, Christian Haass
Published 2020-04-01