Why Is Aneuploidy Associated with Favorable Outcome in Neuroblastoma?

by Gian Paolo Tonini
Published 2021-07-01

Multi-omic profiling of MYCN-amplified neuroblastoma cell-lines

by Erik Dassi, Valentina Greco, Viktoryia Sidarovich, Paola Zuccotti, Natalia Arseni, Paola Scaruffi, Gian Paolo Tonini, Alessandro Quattrone
Published 2015-12-01

Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors

by Sanja Aveic, Marcella Pantile, Pierfrancesco Polo, Viktoryia Sidarovich, Marilena De Mariano, Alessandro Quattrone, Luca Longo, Gian Paolo Tonini
Published 2018-04-01

Autophagic flux inhibition enhances cytotoxicity of the receptor tyrosine kinase inhibitor ponatinib

by Diana Corallo, Fabio Pastorino, Marcella Pantile, Elena Mariotto, Federico Caicci, Giampietro Viola, Mirco Ponzoni, Gian Paolo Tonini, Sanja Aveic
Published 2020-09-01

Impact of interleukin-6 -174 G>C gene promoter polymorphism on neuroblastoma.

by Francesca Totaro, Flora Cimmino, Piero Pignataro, Giovanni Acierno, Marilena De Mariano, Luca Longo, Gian Paolo Tonini, Achille Iolascon, Mario Capasso
Published 2013-01-01

Co-Administration of Fendiline Hydrochloride Enhances Chemotherapeutic Efficacy of Cisplatin in Neuroblastoma Treatment

by Antonella Brizzolara, Patrizia Garbati, Serena Vella, Matilde Calderoni, Alessandro Quattrone, Gian Paolo Tonini, Mario Capasso, Luca Longo, Raffaella Barbieri, Tullio Florio, Aldo Pagano
Published 2020-11-01

A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma.

by Eveline Barbieri, Katleen De Preter, Mario Capasso, Peter Johansson, Tsz-Kwong Man, Zaowen Chen, Paris Stowers, Gian Paolo Tonini, Frank Speleman, Jason M Shohet
Published 2013-01-01

High Genomic Instability Predicts Survival in Metastatic High-Risk Neuroblastoma

by Sara Stigliani, Simona Coco, Stefano Moretti, Andrè Oberthuer, Mattias Fischer, Jessica Theissen, Fabio Gallox, Alberto Garavent, Frank Berthold, Stefano Bonassi, Gian Paolo Tonini, Paola Scaruffi
Published 2012-09-01

MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment

by Patrizia Garbati, Raffaella Barbieri, Davide Cangelosi, Carlo Zanon, Delfina Costa, Alessandra Eva, Stefano Thellung, Matilde Calderoni, Francesca Baldini, Gian Paolo Tonini, Paola Modesto, Tullio Florio, Aldo Pagano
Published 2020-11-01

Expression of FOXP3, CD14, and ARG1 in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival

by Sara Stigliani, Michela Croce, Fabio Morandi, Paola Scaruffi, Valentina Rigo, Barbara Carlini, Carla Manzitti, Anna Rita Gigliotti, Gian Paolo Tonini, Vito Pistoia, Silvano Ferrini, Maria Valeria Corrias
Published 2015-01-01

Bone marrow-infiltrating human neuroblastoma cells express high levels of calprotectin and HLA-G proteins.

by Fabio Morandi, Paola Scaruffi, Fabio Gallo, Sara Stigliani, Stefano Moretti, Stefano Bonassi, Claudio Gambini, Katia Mazzocco, Paolo Fardin, Riccardo Haupt, Giampaolo Arcamone, Italian Cooperative Group for Neuroblastoma, Vito Pistoia, Gian Paolo Tonini, Maria Valeria Corrias
Published 2012-01-01

CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients.

by Ali Rihani, Bram De Wilde, Fjoralba Zeka, Geneviève Laureys, Nadine Francotte, Gian Paolo Tonini, Simona Coco, Rogier Versteeg, Rosa Noguera, Johannes H Schulte, Angelika Eggert, Raymond L Stallings, Frank Speleman, Jo Vandesompele, Tom Van Maerken
Published 2014-01-01

Epigenetic Silencing of DKK3 in Medulloblastoma

by André Oberthuer, Giuseppe Cinalli, Tiziana Servidei, Massimo Zollo, Thomas Hielscher, Massimo Romani, Claudio Brigati, Alfa H.C. Bai, Marc Remke, Marcel Kool, Stefano Moretti, Stefan M. Pfister, Sara Stigliani, Barbara Banelli, Francesca Valdora, Gian Paolo Tonini, Simona Coco
Published 2013-04-01

The p53 Codon 72 Pro/Pro Genotype Identifies Poor-Prognosis Neuroblastoma Patients: Correlation with Reduced Apoptosis and Enhanced Senescence by the p53-72P Isoform

by Sara Cattelani, Giovanna Ferrari-Amorotti, Sara Galavotti, Raffaella Defferrari, Barbara Tanno, Samantha Cialfi, Jenny Vergalli, Valentina Fragliasso, Clara Guerzoni, Gloria Manzotti, Angela Rachele Soliera, Chiara Menin, Roberta Bertorelle, Heather P. McDowell, Alessandro Inserra, Maria Luisa Belli, Luigi Varesio, Deborah Tweddle, Gian Paolo Tonini, Pierluigi Altavista, Carlo Dominici, Giuseppe Raschellà, Bruno Calabretta
Published 2012-07-01

Characterisation and validation of insertions and deletions in 173 patient exomes.

by Francesco Lescai, Silvia Bonfiglio, Chiara Bacchelli, Estelle Chanudet, Aoife Waters, Sanjay M Sisodiya, Dalia Kasperavičiūtė, Julie Williams, Denise Harold, John Hardy, Robert Kleta, Sebahattin Cirak, Richard Williams, John C Achermann, John Anderson, David Kelsell, Tom Vulliamy, Henry Houlden, Nicholas Wood, Una Sheerin, Gian Paolo Tonini, Donna Mackay, Khalid Hussain, Jane Sowden, Veronica Kinsler, Justyna Osinska, Tony Brooks, Mike Hubank, Philip Beales, Elia Stupka
Published 2012-01-01

A G316A Polymorphism in the Ornithine Decarboxylase Gene Promoter Modulates MYCN-Driven Childhood Neuroblastoma

by Laura D. Gamble, Stefania Purgato, Michelle J. Henderson, Simone Di Giacomo, Amanda J. Russell, Paolo Pigini, Jayne Murray, Emanuele Valli, Giorgio Milazzo, Federico M. Giorgi, Mark Cowley, Lesley J. Ashton, Jaydutt Bhalshankar, Gudrun Schleiermacher, Ali Rihani, Tom Van Maerken, Jo Vandesompele, Frank Speleman, Rogier Versteeg, Jan Koster, Angelika Eggert, Rosa Noguera, Raymond L. Stallings, Gian Paolo Tonini, Kwun Fong, Zalman Vaksman, Sharon J. Diskin, John M. Maris, Wendy B. London, Glenn M. Marshall, David S. Ziegler, Michael D. Hogarty, Giovanni Perini, Murray D. Norris, Michelle Haber
Published 2021-04-01