Connectivity Map Analysis Indicates PI3K/Akt/mTOR Inhibitors as Potential Anti-Hypoxia Drugs in Neuroblastoma

by Paolo Uva, Maria Carla Bosco, Alessandra Eva, Massimo Conte, Alberto Garaventa, Loredana Amoroso, Davide Cangelosi
Published 2021-06-01

Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.

by Marzia Ognibene, Davide Cangelosi, Martina Morini, Daniela Segalerba, Maria Carla Bosco, Angela Rita Sementa, Alessandra Eva, Luigi Varesio
Published 2017-01-01

Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a

by Roberta Resaz, Davide Cangelosi, Martina Morini, Daniela Segalerba, Luca Mastracci, Federica Grillo, Maria Carla Bosco, Cristina Bottino, Irma Colombo, Alessandra Eva
Published 2020-09-01

Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming

by Davide Cangelosi, Martina Morini, Nicolò Zanardi, Angela Rita Sementa, Marco Muselli, Massimo Conte, Alberto Garaventa, Ulrich Pfeffer, Maria Carla Bosco, Luigi Varesio, Alessandra Eva
Published 2020-08-01

Transcriptome analysis defines myocardium gene signatures in children with ToF and ASD and reveals disease-specific molecular reprogramming in response to surgery with cardiopulmon...

by Federica Raggi, Davide Cangelosi, Pamela Becherini, Fabiola Blengio, Martina Morini, Massimo Acquaviva, Maria Luisa Belli, Giuseppe Panizzon, Giuseppe Cervo, Luigi Varesio, Alessandra Eva, Maria Carla Bosco
Published 2020-01-01

High-Throughput Gene and Protein Analysis Revealed the Response of Disc Cells to Vitamin D, Depending on the VDR FokI Variants

by Alessandra Colombini, Paola De Luca, Davide Cangelosi, Carlotta Perucca Orfei, Enrico Ragni, Marco Viganò, Michela Malacarne, Mauro Castagnetta, Marco Brayda-Bruno, Domenico Coviello, Laura de Girolamo
Published 2021-09-01

MCM2 and Carbonic Anhydrase 9 Are Novel Potential Targets for Neuroblastoma Pharmacological Treatment

by Patrizia Garbati, Raffaella Barbieri, Davide Cangelosi, Carlo Zanon, Delfina Costa, Alessandra Eva, Stefano Thellung, Matilde Calderoni, Francesca Baldini, Gian Paolo Tonini, Paola Modesto, Tullio Florio, Aldo Pagano
Published 2020-11-01

Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants

by Alessandra Dondero, Martina Morini, Davide Cangelosi, Katia Mazzocco, Martina Serra, Grazia Maria Spaggiari, Gianluca Rotta, Annalisa Tondo, Aurora Castellano, Francesca Scuderi, Angela Rita Sementa, Alessandra Eva, Massimo Conte, Alberto Garaventa, Cristina Bottino, Roberta Castriconi
Published 2021-04-01

Secondary Somatic Mutations in G-Protein-Related Pathways and Mutation Signatures in Uveal Melanoma

by Francesca Piaggio, Veronica Tozzo, Cinzia Bernardi, Michela Croce, Roberto Puzone, Silvia Viaggi, Serena Patrone, Annalisa Barla, Domenico Coviello, Martine J. Jager, Pieter A. van der Velden, Michael Zeschnigk, Davide Cangelosi, Alessandra Eva, Ulrich Pfeffer, Adriana Amaro
Published 2019-10-01

Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration

by Monica Parodi, Federica Raggi, Davide Cangelosi, Claudia Manzini, Mirna Balsamo, Fabiola Blengio, Alessandra Eva, Luigi Varesio, Gabriella Pietra, Gabriella Pietra, Lorenzo Moretta, Maria Cristina Mingari, Maria Cristina Mingari, Maria Cristina Mingari, Massimo Vitale, Maria Carla Bosco
Published 2018-10-01

Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study <...

by Martina Morini, Davide Cangelosi, Daniela Segalerba, Danilo Marimpietri, Federica Raggi, Aurora Castellano, Doriana Fruci, Jaime Font de Mora, Adela Cañete, Yania Yáñez, Virginie Viprey, Maria Valeria Corrias, Barbara Carlini, Annalisa Pezzolo, Gudrun Schleiermacher, Katia Mazzocco, Ruth Ladenstein, Angela Rita Sementa, Massimo Conte, Alberto Garaventa, Susan Burchill, Roberto Luksch, Maria Carla Bosco, Alessandra Eva, Luigi Varesio
Published 2019-09-01