Particulate Matter Air Pollution: Effects on the Cardiovascular System

by Robert B. Hamanaka, Gökhan M. Mutlu
Published 2018-11-01

More to Explore: Further Definition of Risk Factors for COPD – Differential Gender Difference, Modest Elevation in PM2.5, and e-Cigarette Use

by Yixuan Zhang, Lu Wang, Gökhan M. Mutlu, Hua Cai
Published 2021-05-01

IL-6 Inhibition in Critically Ill COVID-19 Patients Is Associated With Increased Secondary Infections

by Lucas M. Kimmig, Lucas M. Kimmig, David Wu, David Wu, Matthew Gold, Natasha N. Pettit, Natasha N. Pettit, David Pitrak, David Pitrak, Jeffrey Mueller, Aliya N. Husain, Ece A. Mutlu, Gökhan M. Mutlu, Gökhan M. Mutlu
Published 2020-10-01

Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase.

by Jennifer La, Eleanor Reed, Lan Chan, Larisa V Smolyaninova, Olga A Akomova, Gökhan M Mutlu, Sergei N Orlov, Nickolai O Dulin
Published 2016-01-01

Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

by Kaitlyn A Sun, Yan Li, Angelo Y Meliton, Parker S Woods, Lucas M Kimmig, Rengül Cetin-Atalay, Robert B Hamanaka, Gökhan M Mutlu
Published 2020-04-01

Nitric oxide prevents alveolar senescence and emphysema in a mouse model.

by Amanda E Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B Murphy, G R Scott Budinger, Gökhan M Mutlu, Toshio Miyata, Douglas E Vaughan
Published 2015-01-01

Alcohol worsens acute lung injury by inhibiting alveolar sodium transport through the adenosine A1 receptor.

by Laura Dada, Angel R Gonzalez, Daniela Urich, Saul Soberanes, Tomas S Manghi, Sergio E Chiarella, Navdeep S Chandel, G R Scott Budinger, Gökhan M Mutlu
Published 2012-01-01

Intermittent Hypoxia-Induced Activation of Endothelial Cells Is Mediated via Sympathetic Activation-Dependent Catecholamine Release

by Rengul Cetin-Atalay, Rengul Cetin-Atalay, Angelo Y. Meliton, Angelo Y. Meliton, David Wu, David Wu, Parker S. Woods, Parker S. Woods, Kaitlyn A. Sun, Kaitlyn A. Sun, Ying-Jie Peng, Ying-Jie Peng, Ying-Jie Peng, Jayasri Nanduri, Jayasri Nanduri, Jayasri Nanduri, Xiaoyu Su, Xiaoyu Su, Xiaoyu Su, Yun Fang, Yun Fang, Yun Fang, Robert B. Hamanaka, Robert B. Hamanaka, Robert B. Hamanaka, Nanduri Prabhakar, Nanduri Prabhakar, Nanduri Prabhakar, Gökhan M. Mutlu, Gökhan M. Mutlu, Gökhan M. Mutlu
Published 2021-07-01

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

by M. Fatih Abasıyanık, Krysta Wolfe, Hoang Van Phan, Jing Lin, Bharathi Laxman, Steven R. White, Philip A. Verhoef, Gökhan M. Mutlu, Bhakti Patel, Savaş Tay
Published 2020-05-01

The effect of rosuvastatin in a murine model of influenza A infection.

by Kathryn A Radigan, Daniela Urich, Alexander V Misharin, Sergio E Chiarella, Saul Soberanes, Angel Gonzalez, Harris Perlman, Richard G Wunderink, G R Scott Budinger, Gökhan M Mutlu
Published 2012-01-01

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

by William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, GR Scott Budigner, Navdeep S Chandel
Published 2014-05-01

Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling

by Eleanor B. Reed, Shawn Ard, Jennifer La, Chan Young Park, Laura Culligan, Jeffrey J. Fredberg, Larisa V. Smolyaninova, Sergei N. Orlov, Bohao Chen, Robert Guzy, Gökhan M. Mutlu, Nickolai O. Dulin
Published 2019-07-01

Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages.

by Kathryn A Radigan, Luisa Morales-Nebreda, Saul Soberanes, Trevor Nicholson, Recep Nigdelioglu, Takugo Cho, Monica Chi, Robert B Hamanaka, Alexander V Misharin, Harris Perlman, G R Scott Budinger, Gökhan M Mutlu
Published 2014-01-01

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

by David Wu, Ru-Ting Huang, Robert B Hamanaka, Matt Krause, Myung-Jin Oh, Cheng-Hsiang Kuo, Recep Nigdelioglu, Angelo Y Meliton, Leah Witt, Guohao Dai, Mete Civelek, Nanduri R Prabhakar, Yun Fang, Gökhan M Mutlu
Published 2017-05-01

Nonclassical Ly6C− Monocytes Drive the Development of Inflammatory Arthritis in Mice

by Alexander V. Misharin, Carla M. Cuda, Rana Saber, Jason D. Turner, Angelica K. Gierut, G. Kenneth Haines III, Sergejs Berdnikovs, Andrew Filer, Andrew R. Clark, Christopher D. Buckley, Gökhan M. Mutlu, G.R. Scott Budinger, Harris Perlman
Published 2014-10-01

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms.

by G R Scott Budinger, Joanne L McKell, Daniela Urich, Nancy Foiles, Ivy Weiss, Sergio E Chiarella, Angel Gonzalez, Saul Soberanes, Andrew J Ghio, Recep Nigdelioglu, Ece A Mutlu, Kathryn A Radigan, David Green, Hau C Kwaan, Gökhan M Mutlu
Published 2011-04-01