Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives.

by Chiara Cipollina, Sonia R Salvatore, Matthew F Muldoon, Bruce A Freeman, Francisco J Schopfer
Published 2014-01-01

Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids[S]

by Marco Fazzari, Dario A. Vitturi, Steven R. Woodcock, Sonia R. Salvatore, Bruce A. Freeman, Francisco J. Schopfer
Published 2019-02-01

Exogenous Nitro-Oleic Acid Treatment Inhibits Primary Root Growth by Reducing the Mitosis in the Meristem in Arabidopsis thaliana

by Luciano M. Di Fino, Ignacio Cerrudo, Sonia R. Salvatore, Francisco J. Schopfer, Carlos García-Mata, Ana M. Laxalt
Published 2020-07-01

Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

by Jeffrey R. Koenitzer, Gustavo Bonacci, Steven R. Woodcock, Chen-Shan Chen, Nadiezhda Cantu-Medellin, Eric E. Kelley, Francisco J. Schopfer
Published 2016-08-01

Nitro-fatty acid pharmacokinetics in the adipose tissue compartment

by Marco Fazzari, NicholasK.H. Khoo, Steven R. Woodcock, Diane K. Jorkasky, Lihua Li, Francisco J. Schopfer, Bruce A. Freeman
Published 2017-02-01

Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine[S]

by Sonia R. Salvatore, Dario A. Vitturi, Paul R.S. Baker, Gustavo Bonacci, Jeffrey R. Koenitzer, Steven R. Woodcock, Bruce A. Freeman, Francisco J. Schopfer
Published 2013-07-01

Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO2) and nitroalkene (RNO2) substituents

by Marco Fazzari, Steven R. Woodcock, Pascal Rowart, Karina Ricart, Jack R. Lancaster, Jr., Rakesh Patel, Dario A. Vitturi, Bruce A. Freeman, Francisco J. Schopfer
Published 2021-05-01

Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism

by Peng Wang, Meaghan E. Killeen, Tina L. Sumpter, Laura K. Ferris, Louis D. Falo, Jr., Bruce A. Freeman, Francisco J. Schopfer, Alicia R. Mathers
Published 2021-07-01

Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

by Matias M. Vazquez, Maria V. Gutierrez, Sonia R. Salvatore, Marcelo Puiatti, Virginia Actis Dato, Gustavo A. Chiabrando, Bruce A. Freeman, Francisco J. Schopfer, Gustavo Bonacci
Published 2020-09-01

Vascepa protects against high-fat diet-induced glucose intolerance, insulin resistance, and impaired β-cell function

by Dana Al Rijjal, Ying Liu, Mi Lai, Youchen Song, Zahra Danaei, Anne Wu, Haneesha Mohan, Li Wei, Francisco J. Schopfer, Feihan F. Dai, Michael B. Wheeler
Published 2021-08-01

Olives and olive oil are sources of electrophilic fatty acid nitroalkenes.

by Marco Fazzari, Andrés Trostchansky, Francisco J Schopfer, Sonia R Salvatore, Beatriz Sánchez-Calvo, Dario Vitturi, Raquel Valderrama, Juan B Barroso, Rafael Radi, Bruce A Freeman, Homero Rubbo
Published 2014-01-01

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

by Soma Jobbagy, Dario A. Vitturi, Sonia R. Salvatore, Lucía Turell, Maria F. Pires, Emilia Kansanen, Carlos Batthyany, Jack R. Lancaster, Jr., Bruce A. Freeman, Francisco J. Schopfer
Published 2019-02-01

In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

by Luis Villacorta, Lucia Minarrieta, Sonia R. Salvatore, Nicholas K. Khoo, Oren Rom, Zhen Gao, Rebecca C. Berman, Soma Jobbagy, Lihua Li, Steven R. Woodcock, Y. Eugene Chen, Bruce A. Freeman, Ana M. Ferreira, Francisco J. Schopfer, Dario A. Vitturi
Published 2018-05-01

CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis

by Kacey J. Prentice, Stacy G. Wendell, Ying Liu, Judith A. Eversley, Sonia R. Salvatore, Haneesha Mohan, Sydney L. Brandt, Andrew C. Adams, X. Serena Wang, David Wei, Garret A. FitzGerald, Timothy B. Durham, Craig D. Hammond, Kyle W. Sloop, Carsten Skarke, Francisco J. Schopfer, Michael B. Wheeler
Published 2018-01-01