Generation and dietary modulation of anti-inflammatory electrophilic omega-3 fatty acid derivatives.

by Chiara Cipollina, Sonia R Salvatore, Matthew F Muldoon, Bruce A Freeman, Francisco J Schopfer
Published 2014-01-01

Redox properties and human serum albumin binding of nitro-oleic acid

by Martina Zatloukalova, Milos Mojovic, Aleksandra Pavicevic, Martin Kabelac, Bruce A. Freeman, Michaela Pekarova, Jan Vacek
Published 2019-06-01

Electrophilic fatty acid nitroalkenes are systemically transported and distributed upon esterification to complex lipids[S]

by Marco Fazzari, Dario A. Vitturi, Steven R. Woodcock, Sonia R. Salvatore, Bruce A. Freeman, Francisco J. Schopfer
Published 2019-02-01

Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

by Valentina Grippo, Milos Mojovic, Aleksandra Pavicevic, Martin Kabelac, Frantisek Hubatka, Jaroslav Turanek, Martina Zatloukalova, Bruce A. Freeman, Jan Vacek
Published 2021-01-01

Nitro-fatty acid pharmacokinetics in the adipose tissue compartment

by Marco Fazzari, NicholasK.H. Khoo, Steven R. Woodcock, Diane K. Jorkasky, Lihua Li, Francisco J. Schopfer, Bruce A. Freeman
Published 2017-02-01

Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis

by Nicholas K.H. Khoo, Marco Fazzari, Dionysios V. Chartoumpekis, Lihua Li, Danielle Aparecida Guimaraes, Gavin E. Arteel, Sruti Shiva, Bruce A. Freeman
Published 2019-04-01

TRP Channel Agonists Activate Different Afferent Neuromodulatory Mechanisms in Guinea Pig Urinary Bladder

by Stephanie L. Daugherty, Jonathan M. Beckel, Kyoungeun A. Kim, Bruce A. Freeman, Jiaxin Liu, Shaoyong Wang, William C. de Groat, Xiulin Zhang
Published 2021-06-01

Characterization and quantification of endogenous fatty acid nitroalkene metabolites in human urine[S]

by Sonia R. Salvatore, Dario A. Vitturi, Paul R.S. Baker, Gustavo Bonacci, Jeffrey R. Koenitzer, Steven R. Woodcock, Bruce A. Freeman, Francisco J. Schopfer
Published 2013-07-01

Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO2) and nitroalkene (RNO2) substituents

by Marco Fazzari, Steven R. Woodcock, Pascal Rowart, Karina Ricart, Jack R. Lancaster, Jr., Rakesh Patel, Dario A. Vitturi, Bruce A. Freeman, Francisco J. Schopfer
Published 2021-05-01

Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism

by Peng Wang, Meaghan E. Killeen, Tina L. Sumpter, Laura K. Ferris, Louis D. Falo, Jr., Bruce A. Freeman, Francisco J. Schopfer, Alicia R. Mathers
Published 2021-07-01

Nitro-oleic acid, a ligand of CD36, reduces cholesterol accumulation by modulating oxidized-LDL uptake and cholesterol efflux in RAW264.7 macrophages

by Matias M. Vazquez, Maria V. Gutierrez, Sonia R. Salvatore, Marcelo Puiatti, Virginia Actis Dato, Gustavo A. Chiabrando, Bruce A. Freeman, Francisco J. Schopfer, Gustavo Bonacci
Published 2020-09-01

Olives and olive oil are sources of electrophilic fatty acid nitroalkenes.

by Marco Fazzari, Andrés Trostchansky, Francisco J Schopfer, Sonia R Salvatore, Beatriz Sánchez-Calvo, Dario Vitturi, Raquel Valderrama, Juan B Barroso, Rafael Radi, Bruce A Freeman, Homero Rubbo
Published 2014-01-01

Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis

by Soma Jobbagy, Dario A. Vitturi, Sonia R. Salvatore, Lucía Turell, Maria F. Pires, Emilia Kansanen, Carlos Batthyany, Jack R. Lancaster, Jr., Bruce A. Freeman, Francisco J. Schopfer
Published 2019-02-01

In situ generation, metabolism and immunomodulatory signaling actions of nitro-conjugated linoleic acid in a murine model of inflammation

by Luis Villacorta, Lucia Minarrieta, Sonia R. Salvatore, Nicholas K. Khoo, Oren Rom, Zhen Gao, Rebecca C. Berman, Soma Jobbagy, Lihua Li, Steven R. Woodcock, Y. Eugene Chen, Bruce A. Freeman, Ana M. Ferreira, Francisco J. Schopfer, Dario A. Vitturi
Published 2018-05-01

Nitro-Oleic Acid (NO₂-OA) Improves Systolic Function in Dilated Cardiomyopathy by Attenuating Myocardial Fibrosis

by Simon Braumann, Wibke Schumacher, Nam Gyu Im, Felix Sebastian Nettersheim, Dennis Mehrkens, Senai Bokredenghel, Alexander Hof, Richard Julius Nies, Christoph Adler, Holger Winkels, Ralph Knöll, Bruce A. Freeman, Volker Rudolph, Anna Klinke, Matti Adam, Stephan Baldus, Martin Mollenhauer, Simon Geißen
Published 2021-08-01

Nitroalkene fatty acids modulate bile acid metabolism and lung function in obese asthma

by Michelle L. Manni, Victoria A. Heinrich, Gregory J. Buchan, James P. O’Brien, Crystal Uvalle, Veronika Cechova, Adolf Koudelka, Dharti Ukani, Mohamad Rawas-Qalaji, Tim D. Oury, Renee Hart, Madeline Ellgass, Steven J. Mullett, Merritt L. Fajt, Sally E. Wenzel, Fernando Holguin, Bruce A. Freeman, Stacy G. Wendell
Published 2021-09-01