Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells

by Niina Bhattarai, Eveliina Korhonen, Yashavanthi Mysore, Kai Kaarniranta, Anu Kauppinen
Published 2021-06-01

Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degen...

by Maria Hytti, Eveliina Korhonen, Heidi Hongisto, Kai Kaarniranta, Heli Skottman, Anu Kauppinen
Published 2021-06-01

Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy

by Niina Piippo, Eveliina Korhonen, Maria Hytti, Kati Kinnunen, Kai Kaarniranta, Anu  Kauppinen
Published 2018-08-01

TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

by Sofia Ranta-aho, Niina Piippo, Eveliina Korhonen, Kai Kaarniranta, Maria Hytti, Anu Kauppinen
Published 2021-05-01

Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells

by Niina Bhattarai, Eveliina Korhonen, Maija Toppila, Ali Koskela, Kai Kaarniranta, Yashavanthi Mysore, Anu Kauppinen
Published 2020-03-01

Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy

by Maria Hytti, Eveliina Korhonen, Juha M. T. Hyttinen, Heidi Roehrich, Kai Kaarniranta, Deborah A. Ferrington, Anu Kauppinen
Published 2019-01-01

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

by Niina Piippo, Eveliina Korhonen, Maria Hytti, Heli Skottman, Kati Kinnunen, Natasha Josifovska, Goran Petrovski, Kai Kaarniranta, Anu Kauppinen
Published 2018-04-01

Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways

by Nicoletta Marchesi, Natthakan Thongon, Alessia Pascale, Alessandro Provenzani, Ali Koskela, Eveliina Korhonen, Adrian Smedowski, Stefano Govoni, Anu Kauppinen, Kai Kaarniranta, Marialaura Amadio
Published 2018-01-01