To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?

by Suvithanandhini Loganathan, Erik M. Lehmkuhl, Randall J. Eck, Randall J. Eck, Daniela C. Zarnescu, Daniela C. Zarnescu
Published 2020-01-01

Glycolysis upregulation is neuroprotective as a compensatory mechanism in ALS

by Ernesto Manzo, Ileana Lorenzini, Dianne Barrameda, Abigail G O'Conner, Jordan M Barrows, Alexander Starr, Tina Kovalik, Benjamin E Rabichow, Erik M Lehmkuhl, Dakotah D Shreiner, Archi Joardar, Jean-Charles Liévens, Robert Bowser, Rita Sattler, Daniela C Zarnescu
Published 2019-06-01

TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6

by Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, Daniela C. Zarnescu
Published 2021-03-01