To Be or Not To Be…Toxic—Is RNA Association With TDP-43 Complexes Deleterious or Protective in Neurodegeneration?

by Suvithanandhini Loganathan, Erik M. Lehmkuhl, Randall J. Eck, Randall J. Eck, Daniela C. Zarnescu, Daniela C. Zarnescu
Published 2020-01-01

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease

by Pamela J. McMillan, Timothy J. Strovas, Misa Baum, Brooke K. Mitchell, Randall J. Eck, Nzinga Hendricks, Jeanna M. Wheeler, Caitlin S. Latimer, C. Dirk Keene, Brian C. Kraemer
Published 2021-06-01

TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6

by Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani B. Siddegowda, Archi Joardar, Hannah Ball, Maria E. Macias, Robert Bowser, Kendall Van Keuren-Jensen, Daniela C. Zarnescu
Published 2021-03-01