Genome wide mapping of UBF binding-sites in mouse and human cell lines

by Jeannine Diesch, Ross D. Hannan, Elaine Sanij
Published 2015-03-01

Harnessing the Nucleolar DNA Damage Response in Cancer Therapy

by Jiachen Xuan, Kezia Gitareja, Natalie Brajanovski, Elaine Sanij
Published 2021-07-01

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

by Jian Kang, Natalie Brajanovski, Keefe T. Chan, Jiachen Xuan, Richard B. Pearson, Elaine Sanij
Published 2021-08-01

The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer

by Shunfei Yan, Daniel Frank, Jinbae Son, Katherine M. Hannan, Ross D. Hannan, Keefe T. Chan, Richard B. Pearson, Elaine Sanij
Published 2017-01-01

Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body.

by Nourdine Hamdane, Victor Y Stefanovsky, Michel G Tremblay, Attila Németh, Eric Paquet, Frédéric Lessard, Elaine Sanij, Ross Hannan, Tom Moss
Published 2014-08-01

rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461

by Jinbae Son, Jinbae Son, Katherine M. Hannan, Katherine M. Hannan, Gretchen Poortinga, Gretchen Poortinga, Gretchen Poortinga, Nadine Hein, Donald P. Cameron, Austen R. D. Ganley, Karen E. Sheppard, Karen E. Sheppard, Karen E. Sheppard, Richard B. Pearson, Richard B. Pearson, Richard B. Pearson, Richard B. Pearson, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Elaine Sanij, Elaine Sanij, Elaine Sanij
Published 2020-07-01

Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells.

by Jeannine Diesch, Elaine Sanij, Omer Gilan, Christopher Love, Hoanh Tran, Nicholas I Fleming, Jason Ellul, Marcia Amalia, Izhak Haviv, Richard B Pearson, Eugene Tulchinsky, John M Mariadason, Oliver M Sieber, Ross D Hannan, Amardeep S Dhillon
Published 2014-01-01

Topoisomerase 1 Inhibition Promotes Cyclic GMP-AMP Synthase-Dependent Antiviral Responses

by Geneviève Pèépin, Charlotte Nejad, Jonathan Ferrand, Belinda J. Thomas, H. James Stunden, Elaine Sanij, Chwan-Hong Foo, Cameron R. Stewart, Jason E. Cain, Philip G. Bardin, Bryan R. G. Williams, Michael P. Gantier, Christine A. Biron
Published 2017-10-01

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

by Elaine Sanij, Katherine M. Hannan, Jiachen Xuan, Shunfei Yan, Jessica E. Ahern, Anna S. Trigos, Natalie Brajanovski, Jinbae Son, Keefe T. Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J. Wakefield, Daniel Frank, Sarah Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J. Deans, Kum Kum Khanna, Linda Mileshkin, Grant A. McArthur, John Soong, Els M. J. J. Berns, Ross D. Hannan, Clare L. Scott, Karen E. Sheppard, Richard B. Pearson
Published 2020-05-01

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

by Olga Kondrashova, Monique Topp, Ksenija Nesic, Elizabeth Lieschke, Gwo-Yaw Ho, Maria I. Harrell, Giada V. Zapparoli, Alison Hadley, Robert Holian, Emma Boehm, Valerie Heong, Elaine Sanij, Richard B. Pearson, John J. Krais, Neil Johnson, Orla McNally, Sumitra Ananda, Kathryn Alsop, Karla J. Hutt, Scott H. Kaufmann, Kevin K. Lin, Thomas C. Harding, Nadia Traficante, Australian Ovarian Cancer Study (AOCS), Anna deFazio, Iain A. McNeish, David D. Bowtell, Elizabeth M. Swisher, Alexander Dobrovic, Matthew J. Wakefield, Clare L. Scott
Published 2018-09-01