rDNA Chromatin Activity Status as a Biomarker of Sensitivity to the RNA Polymerase I Transcription Inhibitor CX-5461

by Jinbae Son, Jinbae Son, Katherine M. Hannan, Katherine M. Hannan, Gretchen Poortinga, Gretchen Poortinga, Gretchen Poortinga, Nadine Hein, Donald P. Cameron, Austen R. D. Ganley, Karen E. Sheppard, Karen E. Sheppard, Karen E. Sheppard, Richard B. Pearson, Richard B. Pearson, Richard B. Pearson, Richard B. Pearson, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Ross D. Hannan, Elaine Sanij, Elaine Sanij, Elaine Sanij
Published 2020-07-01

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis.

by Louise E Kerry, Elaine E Pegg, Donald P Cameron, James Budzak, Gretchen Poortinga, Katherine M Hannan, Ross D Hannan, Gloria Rudenko
Published 2017-03-01

Genomic characterisation of Eμ-Myc mouse lymphomas identifies Bcor as a Myc co-operative tumour-suppressor gene

by Marcus Lefebure, Richard W. Tothill, Elizabeth Kruse, Edwin D. Hawkins, Jake Shortt, Geoffrey M. Matthews, Gareth P. Gregory, Benjamin P. Martin, Madison J. Kelly, Izabela Todorovski, Maria A. Doyle, Richard Lupat, Jason Li, Jan Schroeder, Meaghan Wall, Stuart Craig, Gretchen Poortinga, Don Cameron, Megan Bywater, Lev Kats, Micah D. Gearhart, Vivian J. Bardwell, Ross A. Dickins, Ross D. Hannan, Anthony T. Papenfuss, Ricky W. Johnstone
Published 2017-03-01

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

by Elaine Sanij, Katherine M. Hannan, Jiachen Xuan, Shunfei Yan, Jessica E. Ahern, Anna S. Trigos, Natalie Brajanovski, Jinbae Son, Keefe T. Chan, Olga Kondrashova, Elizabeth Lieschke, Matthew J. Wakefield, Daniel Frank, Sarah Ellis, Carleen Cullinane, Jian Kang, Gretchen Poortinga, Purba Nag, Andrew J. Deans, Kum Kum Khanna, Linda Mileshkin, Grant A. McArthur, John Soong, Els M. J. J. Berns, Ross D. Hannan, Clare L. Scott, Karen E. Sheppard, Richard B. Pearson
Published 2020-05-01