Inhibition of Plasminogen Activator Inhibitor 1 Attenuates Hepatic Steatosis but Does Not Prevent Progressive Nonalcoholic Steatohepatitis in Mice

by Anne S. Henkel, Sadiya S. Khan, Shantel Olivares, Toshio Miyata, Douglas E. Vaughan
Published 2018-12-01

Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis.

by Asish K Ghosh, Sheila B Murphy, Raj Kishore, Douglas E Vaughan
Published 2013-01-01

Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484

by Machteld Sillen, Toshio Miyata, Douglas E. Vaughan, Sergei V. Strelkov, Paul J. Declerck
Published 2021-02-01

The sterol response element binding protein regulates cyclooxygenase-2 gene expression in endothelial cells

by Layton Harris Smith, Matthew S. Petrie, Jason D. Morrow, John A. Oates, Douglas E. Vaughan
Published 2005-05-01

Plasminogen Activator Inhibitor-1 Antagonist TM5484 Attenuates Demyelination and Axonal Degeneration in a Mice Model of Multiple Sclerosis.

by Nicolas Pelisch, Takashi Dan, Atsuhiko Ichimura, Hiroki Sekiguchi, Douglas E Vaughan, Charles van Ypersele de Strihou, Toshio Miyata
Published 2015-01-01

DNA Damage: A Main Determinant of Vascular Aging

by Paula K. Bautista-Niño, Eliana Portilla-Fernandez, Douglas E. Vaughan, A. H. Jan Danser, Anton J. M. Roks
Published 2016-05-01

Epistatic interactions in genetic regulation of t-PA and PAI-1 levels in a Ghanaian population.

by Nadia M Penrod, Kwabena A Poku, Douglas E Vaughan, Folkert W Asselbergs, Nancy J Brown, Jason H Moore, Scott M Williams
Published 2011-01-01

Nitric oxide prevents alveolar senescence and emphysema in a mouse model.

by Amanda E Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B Murphy, G R Scott Budinger, Gökhan M Mutlu, Toshio Miyata, Douglas E Vaughan
Published 2015-01-01

Genetics of Plasminogen Activator Inhibitor-1 (PAI-1) in a Ghanaian Population.

by Marquitta J White, Nuri M Kodaman, Reed H Harder, Folkert W Asselbergs, Douglas E Vaughan, Nancy J Brown, Jason H Moore, Scott M Williams
Published 2015-01-01

Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan

by Rahul Rai, Asish K. Ghosh, Mesut Eren, Alexander R. Mackie, Daniel C. Levine, So-Youn Kim, Jonathan Cedernaes, Veronica Ramirez, Daniele Procissi, Layton H. Smith, Teresa K. Woodruff, Joseph Bass, Douglas E. Vaughan
Published 2017-11-01

Role of PAI-1 in hepatic steatosis and dyslipidemia

by Joshua A. Levine, Carlota Oleaga, Mesut Eren, Ansel P. Amaral, Meng Shang, Elizabeth Lux, Sadiya S. Khan, Sanjiv J. Shah, Yasuhiro Omura, Nathalie Pamir, Joshua Hay, Grant Barish, Toshio Miyata, Hagai Tavori, Sergio Fazio, Douglas E. Vaughan
Published 2021-01-01

Illustrated State‐of‐the‐Art Capsules of the ISTH 2020 Congress

by Robert Ariens, Cecilia Becattini, Markus Bender, Wolfgang Bergmeier, Elisabetta Castoldi, Katrien Devreese, Martin Ellis, David Gailani, Vera Ignjatovic, Paula D. James, Steven Kerrigan, Michele Lambert, Lai Heng Lee, Marcel Levi, Norma Maugeri, Joost Meijers, Juan Melero‐Martin, Alan D. Michelson, Federico Mingozzi, Keith Neeves, Heyu Ni, Anna‐Karin Olsson, Zoltán Prohászka, Marie Ranson, Nicoletta Riva, Yotis Senis, Cornelia H. vanOmmen, Douglas E. Vaughan, John Weisel
Published 2020-07-01