A High Throughput Protein Microarray Approach to Classify HIV Monoclonal Antibodies and Variant Antigens.

by Emmanuel Y Dotsey, Andrea Gorlani, Sampat Ingale, Chad J Achenbach, Donald N Forthal, Philip L Felgner, Johannes S Gach
Published 2015-01-01

Human immunodeficiency virus type-1 (HIV-1) evades antibody-dependent phagocytosis.

by Johannes S Gach, Margaux Bouzin, Marcus P Wong, Veronika Chromikova, Andrea Gorlani, Kuan-Ting Yu, Brijesh Sharma, Enrico Gratton, Donald N Forthal
Published 2017-12-01

HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and are Commonly Detected in Plasma from HIV-infected Humans

by Katherine L. Williams, Valerie Cortez, Adam S. Dingens, Johannes S. Gach, Stephanie Rainwater, Julie F. Weis, Xuemin Chen, Paul Spearman, Donald N. Forthal, Julie Overbaugh
Published 2015-10-01

Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers.

by Ann J Hessell, Eva G Rakasz, Pascal Poignard, Lars Hangartner, Gary Landucci, Donald N Forthal, Wayne C Koff, David I Watkins, Dennis R Burton
Published 2009-05-01

HIV-1 specific antibody titers and neutralization among chronically infected patients on long-term suppressive antiretroviral therapy (ART): a cross-sectional study.

by Johannes S Gach, Chad J Achenbach, Veronika Chromikova, Baiba Berzins, Nina Lambert, Gary Landucci, Donald N Forthal, Christine Katlama, Barbara H Jung, Robert L Murphy
Published 2014-01-01

A human antibody to the CD4 binding site of gp120 capable of highly potent but sporadic cross clade neutralization of primary HIV-1.

by Johannes S Gach, Heribert Quendler, Tommy Tong, Kristin M Narayan, Sean X Du, Robert G Whalen, James M Binley, Donald N Forthal, Pascal Poignard, Michael B Zwick
Published 2013-01-01

Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.

by Valentine U Chukwuma, Mark D Hicar, Xuemin Chen, Katherine J Nicholas, Amanda Joyner, Spyros A Kalams, Gary Landucci, Donald N Forthal, Paul W Spearman, James E Crowe
Published 2015-01-01

HIV-1-Specific Antibody Response and Function after DNA Prime and Recombinant Adenovirus 5 Boost HIV Vaccine in HIV-Infected Subjects.

by Johannes S Gach, Andrea Gorlani, Emmanuel Y Dotsey, Juan C Becerra, Chase T M Anderson, Baiba Berzins, Philip L Felgner, Donald N Forthal, Steven G Deeks, Timothy J Wilkin, Joseph P Casazza, Richard A Koup, Christine Katlama, Brigitte Autran, Robert L Murphy, Chad J Achenbach
Published 2016-01-01

The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.

by Sandeep Gupta, Johannes S Gach, Juan C Becerra, Tran B Phan, Jeffrey Pudney, Zina Moldoveanu, Sarah B Joseph, Gary Landucci, Medalyn Jude Supnet, Li-Hua Ping, Davide Corti, Brian Moldt, Zdenek Hel, Antonio Lanzavecchia, Ruth M Ruprecht, Dennis R Burton, Jiri Mestecky, Deborah J Anderson, Donald N Forthal
Published 2013-01-01

Correction: The Neonatal Fc Receptor (FcRn) Enhances Human Immunodeficiency Virus Type 1 (HIV-1) Transcytosis across Epithelial Cells.

by Sandeep Gupta, Johannes S. Gach, Juan C. Becerra, Tran B. Phan, Jeffrey Pudney, Zina Moldoveanu, Sarah B. Joseph, Gary Landucci, Medalyn Jude Supnet, Li-Hua Ping, Davide Corti, Brian Moldt, Zdenek Hel, Antonio Lanzavecchia, Ruth M. Ruprecht, Dennis R. Burton, Jiri Mestecky, Deborah J. Anderson, Donald N. Forthal
Published 2013-11-01

Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.

by Sampa Santra, Georgia D Tomaras, Ranjit Warrier, Nathan I Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, S Munir Alam, Ruijun Zhang, Sarah L Cocklin, Xiaoying Shen, Ryan Duffy, Shi-Mao Xia, Robert J Schutte, Charles W Pemble Iv, S Moses Dennison, Hui Li, Andrew Chao, Kora Vidnovic, Abbey Evans, Katja Klein, Amit Kumar, James Robinson, Gary Landucci, Donald N Forthal, David C Montefiori, Jaranit Kaewkungwal, Sorachai Nitayaphan, Punnee Pitisuttithum, Supachai Rerks-Ngarm, Merlin L Robb, Nelson L Michael, Jerome H Kim, Kelly A Soderberg, Elena E Giorgi, Lily Blair, Bette T Korber, Christiane Moog, Robin J Shattock, Norman L Letvin, Joern E Schmitz, M A Moody, Feng Gao, Guido Ferrari, George M Shaw, Barton F Haynes
Published 2015-08-01