The 3D Genome as Moderator of Chromosomal Communication

by Dekker, Job, Mirny, Leonid A
Published 2017

Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data

by Dekker, Job, Marti-Renom, Marc A., Mirny, Leonid A.
Published 2015

Condensin promotes the juxtaposition of DNA flanking its loading site in Bacillus Subtilis

by Wang, Xindan, Lajoie, Bryan R., Dekker, Job, Rudner, David Z., Laub, Michael T, Le, Tung
Published 2016

Organization of the Mitotic Chromosome

by Naumova, Natalia, Zhan, Ye, Lajoie, Bryan R., Dekker, Job, Imakaev, Maksim Viktorovich, Fudenberg, Geoffrey, Mirny, Leonid A
Published 2017

Iterative correction of Hi-C data reveals hallmarks of chromosome organization

by Fudenberg, Geoffrey, McCord, Rachel P., Naumova, Natalia, Goloborodko, Anton, Lajoie, Bryan R, Dekker, Job, Imakaev, Maksim Viktorovich, Mirny, Leonid A.
Published 2015

SMC complexes differentially compact mitotic chromosomes according to genomic context

by Schalbetter, Stephanie Andrea, Belton, Jon-Matthew, Miles, Catrina, Yu, Miao, Dekker, Job, Baxter, Jonathan, Goloborodko, Anton, Fudenberg, Geoffrey, Mirny, Leonid A
Published 2018

Extensive Heterogeneity and Intrinsic Variation in Spatial Genome Organization

by Finn, Elizabeth H., Pegoraro, Gianluca, Brandão, Hugo B., Valton, Anne-Laure, Oomen, Marlies E., Dekker, Job, Mirny, Leonid A, Misteli, Tom
Published 2020

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes

by van Berkum, Nynke L., Lieberman-Aiden, Erez, Williams, Louise, Gnirke, Andreas, Dekker, Job, Imakaev, Maksim Viktorovich, Mirny, Leonid A, Lander, Eric Steven
Published 2014

Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization

by Nora, Elphège P., Goloborodko, Anton, Valton, Anne-Laure, Gibcus, Johan H., Uebersohn, Alec, Abdennur, Nezar Alexander, Dekker, Job, Mirny, Leonid A, Bruneau, Benoit G.
Published 2020

Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites

by Liu, Ce Feng, Brandt, Gabriel S., Hoang, Quyen Q., Naumova, Natalia, Lazarevic, Vanja, Hwang, Eun Sook, Dekker, Job, Ringe, Dagmar, Petsko, Gregory A., Glimcher, Laurie H
Published 2017

Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe

by Mizuguchi, Takeshi, Fudenberg, Geoffrey, Mehta, Sameet, Belton, Jon-Matthew, Taneja, Nitika, Folco, Hernan Diego, FitzGerald, Peter, Dekker, Job, Mirny, Leonid A., Barrowman, Jemima, Grewal, Shiv I. S.
Published 2016

A pathway for mitotic chromosome formation

by Gibcus, Johan H., Samejima, Kumiko, Goloborodko, Anton, Samejima, Itaru, Naumova, Natalia, Nubler, Johannes, Kanemaki, Masato T., Xie, Linfeng, Paulson, James R., Earnshaw, William C., Mirny, Leonid A, Dekker, Job
Published 2020

Highly structured homolog pairing reflects functional organization of the Drosophila genome

by AlHaj Abed, Jumana, Erceg, Jelena, Goloborodko, Anton, Nguyen, Son C., McCole, Ruth B., Saylor, Wren, Fudenberg, Geoffrey, Lajoie, Bryan R., Dekker, Job, Mirny, Leonid A., Wu, C.-ting, Goloborodko
Published 2020

The 4D nucleome project

by Dekker, Job, Belmont, Andrew S., Guttman, Mitchell, Leshyk, Victor O., Lis, John T., Lomvardas, Stavros, O'Shea, Clodagh C., Park, Peter J., Ren, Bing, Politz, Joan C. Ritland, Shendure, Jay, Zhong, Sheng, Mirny, Leonid A
Published 2018

Mediator and cohesin connect gene expression and chromatin architecture

by Kagey, Michael H., Newman, Jamie Jennifer, Bilodeau, Steve, Zhan, Ye, Orlando, David A., van Berkum, Nynke L., Ebmeier, Christopher C., Goossens, Jesse, Rahl, Peter B., Levine, Stuart S., Taatjes, Dylan J., Dekker, Job, Young, Richard A.
Published 2012

Systematic evaluation of chromosome conformation capture assays

by Akgol Oksuz, Betul, Yang, Liyan, Abraham, Sameer, Venev, Sergey V, Krietenstein, Nils, Parsi, Krishna Mohan, Ozadam, Hakan, Oomen, Marlies E, Nand, Ankita, Mao, Hui, Genga, Ryan MJ, Maehr, Rene, Rando, Oliver J, Mirny, Leonid A, Gibcus, Johan H, Dekker, Job
Published 2021

Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells

by Kind, Jop, Pagie, Ludo, de Vries, Sandra S, Nahidiazar, Leila, Dey, Siddharth S, Bienko, Magda, Zhan, Ye, Lajoie, Bryan, de Graaf, Carolyn A, Amendola, Mario, Jalink, Kees, Dekker, Job, van Oudenaarden, Alexander, van Steensel, Bas, Fudenberg, Geoffrey, Imakaev, Maksim Viktorovich, Mirny, Leonid A
Published 2017

The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos

by Erceg, Jelena, AlHaj Abed, Jumana, Goloborodko, Anton, Lajoie, Bryan R., Fudenberg, Geoffrey, Abdennur, Nezar Alexander, Imakaev, Maksim Viktorovich, McCole, Ruth B., Nguyen, Son C., Saylor, Wren, Joyce, Eric F., Senaratne, T. Niroshini, Hannan, Mohammed A., Nir, Guy, Dekker, Job, Mirny, Leonid A, Wu, C.-ting
Published 2020

Defining functional DNA elements in the human genome

by Kellis, Manolis, Wold, Barbara, Snyder, Michael P., Bernstein, Bradley E., Kundaje, Anshul, Marinov, Georgi K., Ward, Lucas D., Birney, Ewan, Crawford, Gregory E., Dekker, Job, Dunham, Ian, Elnitski, Laura L., Farnham, Peggy J., Feingold, Elise A., Gerstein, Mark B., Giddings, Morgan C., Gilbert, David M., Gingeras, Thomas R., Green, Eric D., Guigo, Roderic, Hubbard, Tim, Kent, Jim, Lieb, Jason D., Myers, Richard M., Pazin, Michael J., Ren, Bing, Stamatoyannopoulos, John A., Weng, Zhiping, White, Kevin P., Hardison, Ross C.
Published 2014