Lipidome of Atherosclerotic Plaques from Hypercholesterolemic Rabbits

by Lazar A. Bojic, David G. McLaren, Vinit Shah, Stephen F. Previs, Douglas G. Johns, Jose M. Castro-Perez
Published 2014-12-01

Tracking fatty acid kinetics in distinct lipoprotein fractions in vivo: a novel high-throughput approach for studying dyslipidemia in rodent models

by David G. McLaren, Sheng-Ping Wang, Steven J. Stout, Dan Xie, Paul L. Miller, Vivienne Mendoza, Raymond Rosa, Jose Castro-Perez, Stephen F. Previs, Douglas G. Johns, Thomas P. Roddy
Published 2013-01-01

Anacetrapib promotes reverse cholesterol transport and bulk cholesterol excretion in Syrian golden hamsters

by Jose Castro-Perez, François Briand, Karen Gagen, Sheng-Ping Wang, Ying Chen, David G. McLaren, Vinit Shah, Rob J. Vreeken, Thomas Hankemeier, Thierry Sulpice, Thomas P. Roddy, Brian K. Hubbard, Douglas G. Johns
Published 2011-11-01

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

by Jose Castro-Perez, Stephen F. Previs, David G. McLaren, Vinit Shah, Kithsiri Herath, Gowri Bhat, Douglas G. Johns, Sheng-Ping Wang, Lyndon Mitnaul, Kristian Jensen, Robert Vreeken, Thomas Hankemeier, Thomas P. Roddy, Brian K. Hubbard
Published 2011-01-01

Glucagon like receptor 1/ glucagon dual agonist acutely enhanced hepatic lipid clearance and suppressed de novo lipogenesis in mice.

by Vijay R More, Julie Lao, David G McLaren, Anne-Marie Cumiskey, Beth Ann Murphy, Ying Chen, Stephen Previs, Steven Stout, Rajesh Patel, Santhosh Satapati, Wenyu Li, Edward Kowalik, Daphne Szeto, Andrea Nawrocki, Alessandro Pocai, Liangsu Wang, Paul Carrington
Published 2017-01-01

Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux[S]

by David G. McLaren, Stephen F. Previs, Robert D. Phair, Steven J. Stout, Dan Xie, Ying Chen, Gino M. Salituro, Suoyu S. Xu, Jose M. Castro-Perez, Gregory J. Opiteck, Karen O. Akinsanya, Michele A. Cleary, Hayes M. Dansky, Douglas G. Johns, Thomas P. Roddy
Published 2016-03-01

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

by Kristian K. Jensen, Marija Tadin-Strapps, Sheng-ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G. McLaren, Stephen F. Previs, Kithsiri B. Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J. Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O. Akinsanya, Shirly Pinto
Published 2016-12-01

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

by David G. McLaren, Timothy He, Sheng-Ping Wang, Vivienne Mendoza, Raymond Rosa, Karen Gagen, Gowri Bhat, Kithsiri Herath, Paul L. Miller, Sloan Stribling, Andrew Taggart, Jason Imbriglio, Jinqi Liu, Dunlu Chen, Shirly Pinto, James M. Balkovec, Robert J. DeVita, Donald J. Marsh, Jose M. Castro-Perez, Alison Strack, Douglas G. Johns, Stephen F. Previs, Brian K. Hubbard, Thomas P. Roddy
Published 2011-06-01

Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis

by Ji Zhang, Eric S. Muise, Seongah Han, Peter S. Kutchukian, Philippe Costet, Yonghua Zhu, Yanqing Kan, Haihong Zhou, Vinit Shah, Yongcheng Huang, Ashmita Saigal, Taro E. Akiyama, Xiao-Lan Shen, Tian-Quan Cai, Kashmira Shah, Ester Carballo-Jane, Emanuel Zycband, Lan Yi, Ye Tian, Ying Chen, Jason Imbriglio, Elizabeth Smith, Kristine Devito, James Conway, Li-Jun Ma, Maarten Hoek, Iyassu K. Sebhat, Andrea M. Peier, Saswata Talukdar, David G. McLaren, Stephen F. Previs, Kristian K. Jensen, Shirly Pinto
Published 2020-07-01

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S]

by Wu Yin, Ester Carballo-Jane, David G. McLaren, Vivienne H. Mendoza, Karen Gagen, Neil S. Geoghagen, Lesley Ann McNamara, Judith N. Gorski, George J. Eiermann, Aleksandr Petrov, Michael Wolff, Xinchun Tong, Larissa C. Wilsie, Taro E. Akiyama, Jing Chen, Anil Thankappan, Jiyan Xue, Xiaoli Ping, Genevieve Andrews, L. Alexandra Wickham, Cesaire L. Gai, Tu Trinh, Alison A. Kulick, Marcie J. Donnelly, Gregory O. Voronin, Ray Rosa, Anne-Marie Cumiskey, Kavitha Bekkari, Lyndon J. Mitnaul, Oscar Puig, Fabian Chen, Richard Raubertas, Peggy H. Wong, Barbara C. Hansen, Ken S. Koblan, Thomas P. Roddy, Brian K Hubbard, Alison M. Strack
Published 2012-01-01