Lipidome of Atherosclerotic Plaques from Hypercholesterolemic Rabbits

by Lazar A. Bojic, David G. McLaren, Vinit Shah, Stephen F. Previs, Douglas G. Johns, Jose M. Castro-Perez
Published 2014-12-01

In vivo effects of anacetrapib on preβ HDL: improvement in HDL remodeling without effects on cholesterol absorption

by Sheng-Ping Wang, Erin Daniels, Ying Chen, Jose Castro-Perez, Haihong Zhou, Karen O. Akinsanya, Stephen F. Previs, Thomas P. Roddy, Douglas G. Johns
Published 2013-10-01

Analysis of Mammalian Cell Proliferation and Macromolecule Synthesis Using Deuterated Water and Gas Chromatography-Mass Spectrometry

by Victoria C. Foletta, Michelle Palmieri, Joachim Kloehn, Shaun Mason, Stephen F. Previs, Malcolm J. McConville, Oliver M. Sieber, Clinton R. Bruce, Greg M. Kowalski
Published 2016-10-01

Tracking fatty acid kinetics in distinct lipoprotein fractions in vivo: a novel high-throughput approach for studying dyslipidemia in rodent models

by David G. McLaren, Sheng-Ping Wang, Steven J. Stout, Dan Xie, Paul L. Miller, Vivienne Mendoza, Raymond Rosa, Jose Castro-Perez, Stephen F. Previs, Douglas G. Johns, Thomas P. Roddy
Published 2013-01-01

In vivo D2O labeling to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC/MS[S]

by Jose Castro-Perez, Stephen F. Previs, David G. McLaren, Vinit Shah, Kithsiri Herath, Gowri Bhat, Douglas G. Johns, Sheng-Ping Wang, Lyndon Mitnaul, Kristian Jensen, Robert Vreeken, Thomas Hankemeier, Thomas P. Roddy, Brian K. Hubbard
Published 2011-01-01

Quantifying cholesterol synthesis in vivo using 2H2O: enabling back-to-back studies in the same subject

by Stephen F. Previs, Ablatt Mahsut, Alison Kulick, Keiana Dunn, Genevieve Andrews-Kelly, Christopher Johnson, Gowri Bhat, Kithsiri Herath, Paul L. Miller, Sheng-Ping Wang, Karim Azer, Jing Xu, Douglas G. Johns, Brian K. Hubbard, Thomas P. Roddy
Published 2011-07-01

Effects of small interfering RNA-mediated hepatic glucagon receptor inhibition on lipid metabolism in db/db mice[S]

by Seongah Han, Taro E. Akiyama, Stephen F. Previs, Kithsiri Herath, Thomas P. Roddy, Kristian K. Jensen, Hong-Ping Guan, Beth A. Murphy, Lesley A. McNamara, Xun Shen, Walter Strapps, Brian K. Hubbard, Shirly Pinto, Cai Li, Jing Li
Published 2013-10-01

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

by Haihong Zhou, Wenyu Li, Sheng-Ping Wang, Vivienne Mendoza, Raymond Rosa, James Hubert, Kithsiri Herath, Theresa McLaughlin, Rory J. Rohm, Michael E. Lassman, Kenny K. Wong, Douglas G. Johns, Stephen F. Previs, Brian K. Hubbard, Thomas P. Roddy
Published 2012-06-01

Evaluation of CETP activity in vivo under non-steady-state conditions: influence of anacetrapib on HDL-TG flux[S]

by David G. McLaren, Stephen F. Previs, Robert D. Phair, Steven J. Stout, Dan Xie, Ying Chen, Gino M. Salituro, Suoyu S. Xu, Jose M. Castro-Perez, Gregory J. Opiteck, Karen O. Akinsanya, Michele A. Cleary, Hayes M. Dansky, Douglas G. Johns, Thomas P. Roddy
Published 2016-03-01

Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS[S]

by Yi Pan, Haihong Zhou, Ablatt Mahsut, Rory J. Rohm, Olga Berejnaia, Olga Price, Ying Chen, Jose Castro-Perez, Michael E. Lassman, David McLaren, James Conway, Kristian K. Jensen, Tiffany Thomas, Gissette Reyes-Soffer, Henry N. Ginsberg, David E. Gutstein, Michele Cleary, Stephen F. Previs, Thomas P. Roddy
Published 2014-06-01

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

by Santhosh Satapati, Ying Qian, Margaret S. Wu, Aleksandr Petrov, Ge Dai, Sheng-ping Wang, Yonghua Zhu, Xiaolan Shen, Eric S. Muise, Ying Chen, Emanuel Zycband, Adam Weinglass, Jerry Di Salvo, John S. Debenham, Jason M. Cox, Ping Lan, Vinit Shah, Stephen F. Previs, Mark Erion, David E. Kelley, Liangsu Wang, Andrew D. Howard, Jin Shang
Published 2017-08-01

Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey[S]

by Kristian K. Jensen, Marija Tadin-Strapps, Sheng-ping Wang, James Hubert, Yanqing Kan, Yong Ma, David G. McLaren, Stephen F. Previs, Kithsiri B. Herath, Ablatt Mahsut, Andy Liaw, Shubing Wang, Steven J. Stout, CarolAnn Keohan, Gail Forrest, David Coelho, Satya Yendluri, Stephanie Williams, Martin Koser, Steven Bartz, Karen O. Akinsanya, Shirly Pinto
Published 2016-12-01

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

by David G. McLaren, Timothy He, Sheng-Ping Wang, Vivienne Mendoza, Raymond Rosa, Karen Gagen, Gowri Bhat, Kithsiri Herath, Paul L. Miller, Sloan Stribling, Andrew Taggart, Jason Imbriglio, Jinqi Liu, Dunlu Chen, Shirly Pinto, James M. Balkovec, Robert J. DeVita, Donald J. Marsh, Jose M. Castro-Perez, Alison Strack, Douglas G. Johns, Stephen F. Previs, Brian K. Hubbard, Thomas P. Roddy
Published 2011-06-01

Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver.

by Eric S Muise, Hong-Ping Guan, Jinqi Liu, Andrea R Nawrocki, Xiaodong Yang, Chuanlin Wang, Carlos G Rodríguez, Dan Zhou, Judith N Gorski, Marc M Kurtz, Danqing Feng, Kenneth J Leavitt, Lan Wei, Robert R Wilkening, James M Apgar, Shiyao Xu, Ku Lu, Wen Feng, Ying Li, Huaibing He, Stephen F Previs, Xiaolan Shen, Margaret van Heek, Sandra C Souza, Mark J Rosenbach, Tesfaye Biftu, Mark D Erion, David E Kelley, Daniel M Kemp, Robert W Myers, Iyassu K Sebhat
Published 2019-01-01

Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis

by Ji Zhang, Eric S. Muise, Seongah Han, Peter S. Kutchukian, Philippe Costet, Yonghua Zhu, Yanqing Kan, Haihong Zhou, Vinit Shah, Yongcheng Huang, Ashmita Saigal, Taro E. Akiyama, Xiao-Lan Shen, Tian-Quan Cai, Kashmira Shah, Ester Carballo-Jane, Emanuel Zycband, Lan Yi, Ye Tian, Ying Chen, Jason Imbriglio, Elizabeth Smith, Kristine Devito, James Conway, Li-Jun Ma, Maarten Hoek, Iyassu K. Sebhat, Andrea M. Peier, Saswata Talukdar, David G. McLaren, Stephen F. Previs, Kristian K. Jensen, Shirly Pinto
Published 2020-07-01