Heterologous Expression of Immature Forms of Human Islet Amyloid Polypeptide in Yeast Triggers Intracellular Aggregation and Cytotoxicity

by Ana F. Raimundo, Ana F. Raimundo, Ana F. Raimundo, Sofia Ferreira, Sofia Ferreira, Maria I. Farrim, Cláudia N. Santos, Cláudia N. Santos, Cláudia N. Santos, Regina Menezes, Regina Menezes, Regina Menezes
Published 2020-09-01

Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance

by Patrícia Rijo, Milica Pešić, Ana S. Fernandes, Cláudia N. Santos
Published 2020-01-01

From the baker to the bedside: yeast models of Parkinson's disease

by Regina Menezes, Sandra Tenreiro, Diana Macedo, Cláudia N. Santos, Tiago Fleming Outeiro
Published 2015-07-01

Flavonoids as Potential Drugs for <i>VPS13</i>-Dependent Rare Neurodegenerative Diseases

by Piotr Soczewka, Krzysztof Flis, Déborah Tribouillard-Tanvier, Jean-Paul di Rago, Cláudia N. Santos, Regina Menezes, Joanna Kaminska, Teresa Zoladek
Published 2020-07-01

Valuing the Endangered Species Antirrhinum lopesianum: Neuroprotective Activities and Strategies for in vitro Plant Propagation

by Andreia Gomes, Sofia Fortalezas, Rui Pimpão, Inês Figueira, João Maroco, Carlos Aguiar, Ricardo B. Ferreira, Célia Miguel, Cláudia N. Santos
Published 2013-10-01

(Poly)phenol metabolites from Arbutus unedo leaves protect yeast from oxidative injury by activation of antioxidant and protein clearance pathways

by Carolina Jardim, Diana Macedo, Inês Figueira, Gary Dobson, Gordon J. McDougall, Derek Stewart, Ricardo B. Ferreira, Regina Menezes, Cláudia N. Santos
Published 2017-05-01

Brain uptake of hydroxytyrosol and its main circulating metabolites: Protective potential in neuronal cells

by María-Carmen López de las Hazas, Joana Godinho-Pereira, Alba Macià, A. Filipa Almeida, M. Rita Ventura, Maria-José Motilva, Cláudia N. Santos
Published 2018-07-01

Antioxidant Properties and Neuroprotective Capacity of Strawberry Tree Fruit (Arbutus unedo)

by Ricardo B. Ferreira, Derek Stewart, Gordon McDougall, Paula M. Alves, Vera Pontes, Meenu Tyagi, Lucélia Tavares, Rui Pimpão, Sofia Fortalezas, Cláudia N. Santos
Published 2010-02-01

Protective Effect of a (Poly)phenol-Rich Extract Derived from Sweet Cherries Culls against Oxidative Cell Damage

by Ana A. Matias, Rita Rosado-Ramos, Sara L. Nunes, Inês Figueira, Ana Teresa Serra, Maria R. Bronze, Claúdia N. Santos, Catarina M. M. Duarte
Published 2016-03-01

Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases

by Regina Menezes, Alexandre Foito, Carolina Jardim, Inês Costa, Gonçalo Garcia, Rita Rosado-Ramos, Sabine Freitag, Colin James Alexander, Tiago Fleming Outeiro, Derek Stewart, Cláudia N. Santos
Published 2020-08-01

(Poly)phenol-digested metabolites modulate alpha-synuclein toxicity by regulating proteostasis

by Diana Macedo, Carolina Jardim, Inês Figueira, A. Filipa Almeida, Gordon J. McDougall, Derek Stewart, Jose E. Yuste, Francisco A. Tomás-Barberán, Sandra Tenreiro, Tiago F. Outeiro, Cláudia N. Santos
Published 2018-05-01

Phosphorylation modulates clearance of alpha-synuclein inclusions in a yeast model of Parkinson's disease.

by Sandra Tenreiro, Madalena M Reimão-Pinto, Pedro Antas, José Rino, Donata Wawrzycka, Diana Macedo, Rita Rosado-Ramos, Triana Amen, Meytal Waiss, Filipa Magalhães, Andreia Gomes, Cláudia N Santos, Daniel Kaganovich, Tiago Fleming Outeiro
Published 2014-05-01

Phytochemical Composition and Cytotoxic Effects on Liver Hepatocellular Carcinoma Cells of Different Berries Following a Simulated In Vitro Gastrointestinal Digestion

by Francesca Giampieri, Sadia Afrin, Derek Stewart, Gordon J. McDougall, Rex Brennan, Lesley Blyth, Massimiliano Gasparrini, Luca Mazzoni, Franco Capocasa, Josè Miguel Alvarez-Suarez, Stefano Bompadre, Pedro Nogueira Brás de Oliveira, Claudia N. Santos, Manuel Masias, Pablo Agudo, Jorge Crespo, Bruno Mezzetti, Tamara Y. Forbes-Hernández, Maurizio Battino
Published 2018-08-01