GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

by Eva W. Iepsen, Christian T. Have, Simon Veedfald, Sten Madsbad, Jens J. Holst, Niels Grarup, Oluf Pedersen, Ivan Brandslund, Jens-Christian Holm, Torben Hansen, Signe S. Torekov
Published 2020-04-01

Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

by Robina Khan Niazi, Anette P Gjesing, Mette Hollensted, Christian Theil Have, Niels Grarup, Oluf Pedersen, Asmat Ullah, Gulbin Shahid, Wasim Ahmad, Asma Gul, Torben Hansen
Published 2018-11-01

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes.

by Robina Khan Niazi, Jihua Sun, Christian Theil Have, Mette Hollensted, Allan Linneberg, Oluf Pedersen, Jens Steen Nielsen, Jørgen Rungby, Niels Grarup, Torben Hansen, Anette Prior Gjesing
Published 2019-01-01

Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report

by Robina Khan Niazi, Anette Prior Gjesing, Mette Hollensted, Christian Theil Have, Dmitrii Borisevich, Niels Grarup, Oluf Pedersen, Asmat Ullah, Gulbin Shahid, Ifrah Shafqat, Asma Gul, Torben Hansen
Published 2019-09-01

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants.

by Jihua Sun, Christian Theil Have, Mette Hollensted, Niels Grarup, Allan Linneberg, Oluf Pedersen, Jens Steen Nielsen, Jørgen Rungby, Cramer Christensen, Ivan Brandslund, Karsten Kristiansen, Wang Jun, Torben Hansen, Anette P Gjesing
Published 2019-01-01

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents.

by Tenna Ruest Haarmark Nielsen, Emil Vincent Rosenbaum Appel, Mathilde Svendstrup, Johanne Dam Ohrt, Maria Dahl, Cilius Esmann Fonvig, Mette Hollensted, Christian Theil Have, Haja N Kadarmideen, Oluf Pedersen, Torben Hansen, Jens-Christian Holm, Niels Grarup
Published 2017-01-01

Insulin resistance genetic risk score and burden of coronary artery disease in patients referred for coronary angiography.

by Regitze Skals, Maria Lukács Krogager, Emil Vincent R Appel, Theresia M Schnurr, Christian Theil Have, Gunnar Gislason, Henrik Enghusen Poulsen, Lars Køber, Thomas Engstrøm, Steen Stender, Torben Hansen, Niels Grarup, Christina Ji-Young Lee, Charlotte Andersson, Christian Torp-Pedersen, Peter E Weeke
Published 2021-01-01

Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography.

by Maria Lukács Krogager, Regitze Kuhr Skals, Emil Vincent R Appel, Theresia M Schnurr, Line Engelbrechtsen, Christian Theil Have, Oluf Pedersen, Thomas Engstrøm, Dan M Roden, Gunnar Gislason, Henrik Enghusen Poulsen, Lars Køber, Steen Stender, Torben Hansen, Niels Grarup, Charlotte Andersson, Christian Torp-Pedersen, Peter E Weeke
Published 2018-01-01

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology.

by Theresia M Schnurr, Anette P Gjesing, Camilla H Sandholt, Anna Jonsson, Yuvaraj Mahendran, Christian T Have, Claus T Ekstrøm, Anne-Louise Bjerregaard, Soren Brage, Daniel R Witte, Marit E Jørgensen, Mette Aadahl, Betina H Thuesen, Allan Linneberg, Hans Eiberg, Oluf Pedersen, Niels Grarup, Tuomas O Kilpeläinen, Torben Hansen
Published 2016-01-01

Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations.

by Charlotte Andersson, Maria Lukács Krogager, Regitze Kuhr Skals, Emil Vincent Rosenbaum Appel, Christian Theil Have, Niels Grarup, Oluf Pedersen, Jørgen L Jeppesen, Ole Dyg Pedersen, Helena Dominguez, Ulrik Dixen, Thomas Engstrøm, Niels Tønder, Dan M Roden, Steen Stender, Gunnar H Gislason, Henrik Enghusen-Poulsen, Torben Hansen, Lars Køber, Christian Torp-Pedersen, Peter E Weeke
Published 2019-01-01

Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

by Laura Andreasen, Laura Andreasen, Jonas Ghouse, Jonas Ghouse, Morten W. Skov, Morten W. Skov, Christian T. Have, Gustav Ahlberg, Gustav Ahlberg, Peter V. Rasmussen, Peter V. Rasmussen, Allan Linneberg, Allan Linneberg, Allan Linneberg, Oluf Pedersen, Pyotr G. Platonov, Stig Haunsø, Stig Haunsø, Stig Haunsø, Jesper H. Svendsen, Jesper H. Svendsen, Jesper H. Svendsen, Torben Hansen, Jørgen K. Kanters, Morten S. Olesen, Morten S. Olesen
Published 2018-07-01

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

by Suzanne Vogelezang, Jonathan P Bradfield, Tarunveer S Ahluwalia, John A Curtin, Timo A Lakka, Niels Grarup, Markus Scholz, Peter J van der Most, Claire Monnereau, Evie Stergiakouli, Anni Heiskala, Momoko Horikoshi, Iryna O Fedko, Natalia Vilor-Tejedor, Diana L Cousminer, Marie Standl, Carol A Wang, Jorma Viikari, Frank Geller, Carmen Íñiguez, Niina Pitkänen, Alessandra Chesi, Jonas Bacelis, Loic Yengo, Maties Torrent, Ioanna Ntalla, Øyvind Helgeland, Saskia Selzam, Judith M Vonk, Mohammed H Zafarmand, Barbara Heude, Ismaa Sadaf Farooqi, Akram Alyass, Robin N Beaumont, Christian T Have, Peter Rzehak, Jose Ramon Bilbao, Theresia M Schnurr, Inês Barroso, Klaus Bønnelykke, Lawrence J Beilin, Lisbeth Carstensen, Marie-Aline Charles, Bo Chawes, Karine Clément, Ricardo Closa-Monasterolo, Adnan Custovic, Johan G Eriksson, Joaquin Escribano, Maria Groen-Blokhuis, Veit Grote, Dariusz Gruszfeld, Hakon Hakonarson, Torben Hansen, Andrew T Hattersley, Mette Hollensted, Jouke-Jan Hottenga, Elina Hyppönen, Stefan Johansson, Raimo Joro, Mika Kähönen, Ville Karhunen, Wieland Kiess, Bridget A Knight, Berthold Koletzko, Andreas Kühnapfel, Kathrin Landgraf, Jean-Paul Langhendries, Terho Lehtimäki, Jaakko T Leinonen, Aihuali Li, Virpi Lindi, Estelle Lowry, Mariona Bustamante, Carolina Medina-Gomez, Mads Melbye, Kim F Michaelsen, Camilla S Morgen, Trevor A Mori, Tenna R H Nielsen, Harri Niinikoski, Albertine J Oldehinkel, Katja Pahkala, Kalliope Panoutsopoulou, Oluf Pedersen, Craig E Pennell, Christine Power, Sijmen A Reijneveld, Fernando Rivadeneira, Angela Simpson, Peter D Sly, Jakob Stokholm, Kook K Teo, Elisabeth Thiering, Nicholas J Timpson, André G Uitterlinden, Catharina E M van Beijsterveldt, Barbera D C van Schaik, Marc Vaudel, Elvira Verduci, Rebecca K Vinding, Mandy Vogel, Eleftheria Zeggini, Sylvain Sebert, Mads V Lind, Christopher D Brown, Loreto Santa-Marina, Eva Reischl, Christine Frithioff-Bøjsøe, David Meyre, Eleanor Wheeler, Ken Ong, Ellen A Nohr, Tanja G M Vrijkotte, Gerard H Koppelman, Robert Plomin, Pål R Njølstad, George D Dedoussis, Philippe Froguel, Thorkild I A Sørensen, Bo Jacobsson, Rachel M Freathy, Babette S Zemel, Olli Raitakari, Martine Vrijheid, Bjarke Feenstra, Leo-Pekka Lyytikäinen, Harold Snieder, Holger Kirsten, Patrick G Holt, Joachim Heinrich, Elisabeth Widén, Jordi Sunyer, Dorret I Boomsma, Marjo-Riitta Järvelin, Antje Körner, George Davey Smith, Jens-Christian Holm, Mustafa Atalay, Clare Murray, Hans Bisgaard, Mark I McCarthy, Early Growth Genetics Consortium, Vincent W V Jaddoe, Struan F A Grant, Janine F Felix
Published 2020-10-01