ARDS Subphenotypes: Understanding a Heterogeneous Syndrome

by Jennifer G. Wilson, Carolyn S. Calfee
Published 2020-03-01

A manifesto for the future of ICU trials

by Ewan C. Goligher, Fernando Zampieri, Carolyn S. Calfee, Christopher W. Seymour
Published 2020-12-01

Long-term ozone exposure is positively associated with telomere length in critically ill patients

by Chunxue Wang, Paul J. Wolters, Carolyn S. Calfee, Shuo Liu, John R. Balmes, Zhiguo Zhao, Tatsuki Koyama, Lorraine B. Ware
Published 2020-08-01

Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

by Luis Morales-Quinteros, Marcus J. Schultz, Josep Bringué, Carolyn S. Calfee, Marta Camprubí, Olaf L. Cremer, Janneke Horn, Tom van der Poll, Pratik Sinha, Antonio Artigas, Lieuwe D. Bos, MARS Consortium
Published 2019-11-01

Alternative Tobacco Product Use in Critically Ill Patients

by Tom Liu, Thomas J. Deiss, Matthew W. Lippi, Alejandra Jauregui, Kathryn Vessel, Serena Ke, Annika Belzer, Hanjing Zhuo, Kirsten N. Kangelaris, Antonio D. Gomez, Michael A. Matthay, Kathleen D. Liu, Carolyn S. Calfee
Published 2020-11-01

Accuracy of the Radiographic Assessment of Lung Edema Score for the Diagnosis of ARDS

by Claudio Zimatore, Claudio Zimatore, Luigi Pisani, Luigi Pisani, Luigi Pisani, Valeria Lippolis, Melissa A. Warren, Carolyn S. Calfee, Lorraine B. Ware, Lorraine B. Ware, Anna Geke Algera, Marry R. Smit, Salvatore Grasso, Marcus J. Schultz, Marcus J. Schultz
Published 2021-05-01

Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research

by Lieuwe D.J. Bos, Antonio Artigas, Jean-Michel Constantin, Laura A. Hagens, Nanon Heijnen, John G. Laffey, Nuala Meyer, Laurent Papazian, Lara Pisani, Marcus J. Schultz, Manu Shankar-Hari, Marry R. Smit, Charlotte Summers, Lorraine B. Ware, Raffaele Scala, Carolyn S. Calfee
Published 2021-02-01

Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs

by Manu Shankar-Hari, Shalini Santhakumaran, A Toby Prevost, Josie K Ward, Timothy Marshall, Claire Bradley, Carolyn S Calfee, Kevin L Delucchi, Pratik Sinha, Michael A Matthay, Jonathan Hackett, Cliona McDowell, John G Laffey, Anthony Gordon, Cecilia M O’Kane, Daniel F McAuley
Published 2021-07-01

Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study

by Brian J. Anderson, Carolyn S. Calfee, Kathleen D. Liu, John P. Reilly, Kirsten N. Kangelaris, Michael G. S. Shashaty, Aili L. Lazaar, Andrew I. Bayliffe, Robert J. Gallop, Todd A. Miano, Thomas G. Dunn, Erik Johansson, Jason Abbott, Alejandra Jauregui, Thomas Deiss, Kathryn Vessel, Annika Belzer, Hanjing Zhuo, Michael A. Matthay, Nuala J. Meyer, Jason D. Christie
Published 2019-12-01

Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses

by Eran Mick, Jack Kamm, Angela Oliveira Pisco, Kalani Ratnasiri, Jennifer M. Babik, Gloria Castañeda, Joseph L. DeRisi, Angela M. Detweiler, Samantha L. Hao, Kirsten N. Kangelaris, G. Renuka Kumar, Lucy M. Li, Sabrina A. Mann, Norma Neff, Priya A. Prasad, Paula Hayakawa Serpa, Sachin J. Shah, Natasha Spottiswoode, Michelle Tan, Carolyn S. Calfee, Stephanie A. Christenson, Amy Kistler, Charles Langelier
Published 2020-11-01

Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma.

by Jason D Christie, Mark M Wurfel, Rui Feng, Grant E O'Keefe, Jonathan Bradfield, Lorraine B Ware, David C Christiani, Carolyn S Calfee, Mitchell J Cohen, Michael Matthay, Nuala J Meyer, Cecilia Kim, Mingyao Li, Joshua Akey, Kathleen C Barnes, Jonathan Sevransky, Paul N Lanken, Addison K May, Richard Aplenc, James P Maloney, Hakon Hakonarson, Trauma ALI SNP Consortium (TASC) investigators
Published 2012-01-01

Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis

by Adrien Carla, Bruno Pereira, Hanifa Boukail, Jules Audard, Nathalie Pinol-Domenech, Manuela De Carvalho, Raiko Blondonnet, Ruoyang Zhai, Dominique Morand, Céline Lambert, Vincent Sapin, Lorraine B. Ware, Carolyn S. Calfee, Julie A. Bastarache, John G. Laffey, Nicole P. Juffermans, Lieuwe D. Bos, Antonio Artigas, Patricia R. M. Rocco, Michael A. Matthay, Daniel F. McAuley, Jean-Michel Constantin, Matthieu Jabaudon, for the ESICM Translational Biology Group of the Acute Respiratory Failure section
Published 2020-04-01

Plasma Metabolites in Early Sepsis Identify Distinct Clusters Defined by Plasma Lipids

by Angela J. Rogers, MD, MPH, Aleksandra Leligdowicz, MD, PhD, Kévin Contrepois, PhD, Alejandra Jauregui, BSc, Kathryn Vessel, BSc, Thomas J. Deiss, BSc, Annika Belzer, BSc, Tom Liu, MD, Matthew Lippi, MD, MPH, Serena Ke, BSc, Erin Ross, BSc, Hanjing Zhou, MSc, Carolyn Hendrickson, MD, MAS, Antonio Gomez, MD, Pratik Sinha, MD, PhD, Kirsten N. Kangelaris, MD, Kathleen D. Liu, MD, PhD, Carolyn S. Calfee, MD, MAS, Michael A. Matthay, MD
Published 2021-08-01

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS

by Aartik Sarma, Stephanie A. Christenson, Ashley Byrne, Eran Mick, Angela Oliveira Pisco, Catherine DeVoe, Thomas Deiss, Rajani Ghale, Beth Shoshana Zha, Alexandra Tsitsiklis, Alejandra Jauregui, Farzad Moazed, Angela M. Detweiler, Natasha Spottiswoode, Pratik Sinha, Norma Neff, Michelle Tan, Paula Hayakawa Serpa, Andrew Willmore, K. Mark Ansel, Jennifer G. Wilson, Aleksandra Leligdowicz, Emily R. Siegel, Marina Sirota, Joseph L. DeRisi, Michael A. Matthay, COMET Consortium, Carolyn M. Hendrickson, Kirsten N. Kangelaris, Matthew F. Krummel, Prescott G. Woodruff, David J. Erle, Carolyn S. Calfee, Charles R. Langelier
Published 2021-08-01