A manifesto for the future of ICU trials

by Ewan C. Goligher, Fernando Zampieri, Carolyn S. Calfee, Christopher W. Seymour
Published 2020-12-01

Arguing for Adaptive Clinical Trials in Sepsis

by Victor B. Talisa, Sachin Yende, Christopher W. Seymour, Derek C. Angus
Published 2018-06-01

The global burden of sepsis: barriers and potential solutions

by Kristina E. Rudd, Niranjan Kissoon, Direk Limmathurotsakul, Sotharith Bory, Birungi Mutahunga, Christopher W. Seymour, Derek C. Angus, T. Eoin West
Published 2018-09-01

Precision medicine for all? Challenges and opportunities for a precision medicine approach to critical illness

by Christopher W. Seymour, Hernando Gomez, Chung-Chou H. Chang, Gilles Clermont, John A. Kellum, Jason Kennedy, Sachin Yende, Derek C. Angus
Published 2017-10-01

Comparing the validity of different ICD coding abstraction strategies for sepsis case identification in German claims data.

by Carolin Fleischmann-Struzek, Daniel O Thomas-Rüddel, Anna Schettler, Daniel Schwarzkopf, Angelika Stacke, Christopher W Seymour, Christoph Haas, Ulf Dennler, Konrad Reinhart
Published 2018-01-01

Geographic access to high capability severe acute respiratory failure centers in the United States.

by David J Wallace, Derek C Angus, Christopher W Seymour, Donald M Yealy, Brendan G Carr, Kristen Kurland, Arthur Boujoukos, Jeremy M Kahn
Published 2014-01-01

Murine sepsis phenotypes and differential treatment effects in a randomized trial of prompt antibiotics and fluids

by Christopher W. Seymour, Samantha J. Kerti, Anthony J. Lewis, Jason Kennedy, Emily Brant, John E. Griepentrog, Xianghong Zhang, Derek C. Angus, Chung-Chou H. Chang, Matthew R. Rosengart
Published 2019-11-01

Strategies to Promote ResiliencY (SPRY): a randomised embedded multifactorial adaptative platform (REMAP) clinical trial protocol to study interventions to improve recovery after s...

by Derek C Angus, Jennifer Holder-Murray, Katherine Moll Reitz, Christopher W Seymour, Jennifer Vates, Melanie Quintana, Kert Viele, Michelle Detry, Michael Morowitz, Alison Morris, Barbara Methe, Jason Kennedy, Brian Zuckerbraun, Timothy D Girard, Oscar C Marroquin, Stephen Esper, Anne B Newman, Scott Berry, Matthew Neal
Published 2020-09-01

The UPMC OPTIMISE-C19 (OPtimizing Treatment and Impact of Monoclonal antIbodieS through Evaluation for COVID-19) trial: a structured summary of a study protocol for an open-label,...

by David T. Huang, Erin K. McCreary, J. Ryan Bariola, Richard J. Wadas, Kevin E. Kip, Oscar C. Marroquin, Stephen Koscumb, Kevin Collins, Judith A. Shovel, Mark Schmidhofer, Mary Kay Wisniewski, Colleen Sullivan, Donald M. Yealy, Meredith Axe, David A. Nace, Ghady Haidar, Tina Khadem, Kelsey Linstrum, Graham M. Snyder, Christopher W. Seymour, Stephanie K. Montgomery, Bryan J. McVerry, Lindsay Berry, Scott Berry, Russell Meyers, Alexandra Weissman, Octavia M. Peck-Palmer, Alan Wells, Robert Bart, Debbie L. Albin, Tami Minnier, Derek C. Angus
Published 2021-05-01