Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

by Gwendoline Bourré, François-Xavier Cantrelle, Amina Kamah, Béatrice Chambraud, Isabelle Landrieu, Caroline Smet-Nocca
Published 2018-10-01

A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes

by Hélène Léger, Caroline Smet-Nocca, Amel Attmane-Elakeb, Sara Morley-Fletcher, Arndt G. Benecke, Sebastian Eilebrecht
Published 2014-02-01

Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregat...

by François-Xavier Cantrelle, François-Xavier Cantrelle, Anne Loyens, Xavier Trivelli, Oliver Reimann, Oliver Reimann, Clément Despres, Neha S. Gandhi, Christian P. R. Hackenberger, Christian P. R. Hackenberger, Isabelle Landrieu, Isabelle Landrieu, Caroline Smet-Nocca, Caroline Smet-Nocca
Published 2021-06-01

NMR Meets Tau: Insights into Its Function and Pathology

by Guy Lippens, Isabelle Landrieu, Caroline Smet, Isabelle Huvent, Neha S. Gandhi, Benoît Gigant, Clément Despres, Haoling Qi, Juan Lopez
Published 2016-06-01

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

by Isabelle Landrieu, Caroline Smet-Nocca, Laziza Amniai, Justin Vijay Louis, Jean-Michel Wieruszeski, Jozef Goris, Veerle Janssens, Guy Lippens
Published 2011-01-01

50nm-scale localization of single unmodified, isotopically enriched, proteins in cells.

by Anthony Delaune, Armelle Cabin-Flaman, Guillaume Legent, David Gibouin, Caroline Smet-Nocca, Fabrice Lefebvre, Arndt Benecke, Marc Vasse, Camille Ripoll
Published 2013-01-01

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

by Pascale Barbier, Orgeta Zejneli, Orgeta Zejneli, Marlène Martinho, Alessia Lasorsa, Valérie Belle, Caroline Smet-Nocca, Philipp O. Tsvetkov, François Devred, Isabelle Landrieu
Published 2019-08-01

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.

by Peter Borghgraef, Clément Menuet, Clara Theunis, Justin V Louis, Herman Devijver, Hervé Maurin, Caroline Smet-Nocca, Guy Lippens, Gerard Hilaire, Harrie Gijsen, Dieder Moechars, Fred Van Leuven
Published 2013-01-01

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

by Yann Fichou, Youssra K. Al-Hilaly, François Devred, Caroline Smet-Nocca, Philipp O. Tsvetkov, Joke Verelst, Joris Winderickx, Nick Geukens, Eugeen Vanmechelen, Audrey Perrotin, Louise Serpell, Bernard J Hanseeuw, Miguel Medina, Luc Buée, Isabelle Landrieu
Published 2019-03-01