Secretion of Clostridium difficile toxins A and B requires the holin-like protein TcdE.

by Revathi Govind, Bruno Dupuy
Published 2012-01-01

The Regulatory Networks That Control Clostridium difficile Toxin Synthesis

by Isabelle Martin-Verstraete, Johann Peltier, Bruno Dupuy
Published 2016-05-01

Pleiotropic roles of Clostridium difficile sin locus.

by Brintha Parasumanna Girinathan, Junjun Ou, Bruno Dupuy, Revathi Govind
Published 2018-03-01

Wolf in Sheep’s Clothing: <i>Clostridioides difficile</i> Biofilm as a Reservoir for Recurrent Infections

by Jazmin Meza-Torres, Emile Auria, Bruno Dupuy, Yannick D. N. Tremblay
Published 2021-09-01

Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis.

by Imad Kansau, Amira Barketi-Klai, Marc Monot, Sandra Hoys, Bruno Dupuy, Claire Janoir, Anne Collignon
Published 2016-01-01

Clostridium difficile Biofilm: Remodeling Metabolism and Cell Surface to Build a Sparse and Heterogeneously Aggregated Architecture

by Isabelle Poquet, Isabelle Poquet, Laure Saujet, Laure Saujet, Alexis Canette, Marc Monot, Marc Monot, Jovanna Mihajlovic, Jean-Marc Ghigo, Olga Soutourina, Olga Soutourina, Romain Briandet, Isabelle Martin-Verstraete, Isabelle Martin-Verstraete, Bruno Dupuy, Bruno Dupuy
Published 2018-09-01

Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR.

by Imane El Meouche, Johann Peltier, Marc Monot, Olga Soutourina, Martine Pestel-Caron, Bruno Dupuy, Jean-Louis Pons
Published 2013-01-01

Phylogenomic analysis supports the ancestral presence of LPS-outer membranes in the Firmicutes

by Luisa CS Antunes, Daniel Poppleton, Andreas Klingl, Alexis Criscuolo, Bruno Dupuy, Céline Brochier-Armanet, Christophe Beloin, Simonetta Gribaldo
Published 2016-08-01

Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation.

by Hedwig Kurka, Armin Ehrenreich, Wolfgang Ludwig, Marc Monot, Maja Rupnik, Frederic Barbut, Alexander Indra, Bruno Dupuy, Wolfgang Liebl
Published 2014-01-01

A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σK and the Fidelity of Spore Development in Clostridium difficile.

by Mónica Serrano, Nicolas Kint, Fátima C Pereira, Laure Saujet, Pierre Boudry, Bruno Dupuy, Adriano O Henriques, Isabelle Martin-Verstraete
Published 2016-09-01

Expanding the RpoS/σS-network by RNA sequencing and identification of σS-controlled small RNAs in Salmonella.

by Corinne Lévi-Meyrueis, Véronique Monteil, Odile Sismeiro, Marie-Agnès Dillies, Marc Monot, Bernd Jagla, Jean-Yves Coppée, Bruno Dupuy, Françoise Norel
Published 2014-01-01

Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291

by Brintha P. Girinathan, Marc Monot, Daniel Boyle, Kathleen N. McAllister, Joseph A. Sorg, Bruno Dupuy, Revathi Govind, Craig D. Ellermeier
Published 2017-02-01

The flagellin FliC of Clostridium difficile is responsible for pleiotropic gene regulation during in vivo infection.

by Amira Barketi-Klai, Marc Monot, Sandra Hoys, Sylvie Lambert-Bordes, Sarah A Kuehne, Nigel Minton, Anne Collignon, Bruno Dupuy, Imad Kansau
Published 2014-01-01

The spore differentiation pathway in the enteric pathogen Clostridium difficile.

by Fátima C Pereira, Laure Saujet, Ana R Tomé, Mónica Serrano, Marc Monot, Evelyne Couture-Tosi, Isabelle Martin-Verstraete, Bruno Dupuy, Adriano O Henriques
Published 2013-01-01

Genome-wide analysis of cell type-specific gene transcription during spore formation in Clostridium difficile.

by Laure Saujet, Fátima C Pereira, Monica Serrano, Olga Soutourina, Marc Monot, Pavel V Shelyakin, Mikhail S Gelfand, Bruno Dupuy, Adriano O Henriques, Isabelle Martin-Verstraete
Published 2013-01-01

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile.

by Olga A Soutourina, Marc Monot, Pierre Boudry, Laure Saujet, Christophe Pichon, Odile Sismeiro, Ekaterina Semenova, Konstantin Severinov, Chantal Le Bouguenec, Jean-Yves Coppée, Bruno Dupuy, Isabelle Martin-Verstraete
Published 2013-05-01

Genome-Wide Transcription Start Site Mapping and Promoter Assignments to a Sigma Factor in the Human Enteropathogen Clostridioides difficile

by Olga Soutourina, Olga Soutourina, Olga Soutourina, Thomas Dubois, Marc Monot, Pavel V. Shelyakin, Laure Saujet, Pierre Boudry, Mikhail S. Gelfand, Mikhail S. Gelfand, Bruno Dupuy, Isabelle Martin-Verstraete, Isabelle Martin-Verstraete
Published 2020-08-01

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile

by Sandra Wydau-Dematteis, Imane El Meouche, Pascal Courtin, Audrey Hamiot, René Lai-Kuen, Bruno Saubaméa, François Fenaille, Marie-José Butel, Jean-Louis Pons, Bruno Dupuy, Marie-Pierre Chapot-Chartier, Johann Peltier
Published 2018-06-01

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile.

by Glen P Carter, Gillian R Douce, Revathi Govind, Pauline M Howarth, Kate E Mackin, Janice Spencer, Anthony M Buckley, Ana Antunes, Despina Kotsanas, Grant A Jenkin, Bruno Dupuy, Julian I Rood, Dena Lyras
Published 2011-10-01