Preanalytical Stability of CSF Total and Oligomeric Alpha-Synuclein

by Ilham Y. Abdi, Nour K. Majbour, Eline A. J. Willemse, Wilma D. J. van de Berg, Brit Mollenhauer, Brit Mollenhauer, Charlotte E. Teunissen, Omar M. El-Agnaf
Published 2021-03-01

Blood Contamination in CSF and Its Impact on Quantitative Analysis of Alpha-Synuclein

by Katalin Barkovits, Niels Kruse, Andreas Linden, Lars Tönges, Kathy Pfeiffer, Brit Mollenhauer, Katrin Marcus
Published 2020-02-01

Metabolic profiling of body fluids and multivariate data analysis

by Jean-Pierre Trezzi, Christian Jäger, Sara Galozzi, Katalin Barkovits, Katrin Marcus, Brit Mollenhauer, Karsten Hiller
Published 2017-01-01

Combined Analysis of CSF Tau, Aβ42, Aβ1–42% and Aβ1–40ox% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia

by Mirko Bibl, Hermann Esselmann, Piotr Lewczuk, Claudia Trenkwalder, Markus Otto, Johannes Kornhuber, Jens Wiltfang, Brit Mollenhauer
Published 2010-01-01

Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC

by Viktoria C. Ruf, Song Shi, Felix Schmidt, Daniel Weckbecker, Georg S. Nübling, Uwe Ködel, Brit Mollenhauer, Armin Giese
Published 2020-05-01

A First Tetraplex Assay for the Simultaneous Quantification of Total α-Synuclein, Tau, β-Amyloid42 and DJ-1 in Human Cerebrospinal Fluid.

by Niels Kruse, Michael G Schlossmacher, Walter J Schulz-Schaeffer, Eugeen Vanmechelen, Hugo Vanderstichele, Omar M El-Agnaf, Brit Mollenhauer
Published 2016-01-01

Protein variability in cerebrospinal fluid and its possible implications for neurological protein biomarker research.

by Lukas M Schilde, Steffen Kösters, Simone Steinbach, Karin Schork, Martin Eisenacher, Sara Galozzi, Michael Turewicz, Katalin Barkovits, Brit Mollenhauer, Katrin Marcus, Caroline May
Published 2018-01-01

Elemental fingerprint: Reassessment of a cerebrospinal fluid biomarker for Parkinson's disease

by Fabian Maass, Bernhard Michalke, Desiree Willkommen, Andreas Leha, Claudia Schulte, Lars Tönges, Brit Mollenhauer, Claudia Trenkwalder, Daniel Rückamp, Matthias Börger, Inga Zerr, Mathias Bähr, Paul Lingor
Published 2020-02-01

Peripheral decarboxylase inhibitors paradoxically induce aromatic L-amino acid decarboxylase

by Anouke van Rumund, Lukas Pavelka, Rianne A. J. Esselink, Ben P. M. Geurtz, Ron A. Wevers, Brit Mollenhauer, Rejko Krüger, Bastiaan R. Bloem, Marcel M. Verbeek
Published 2021-03-01

Interlaboratory validation of cerebrospinal fluid α‐synuclein quantification in the diagnosis of sporadic Creutzfeldt‐Jakob disease

by Niels Kruse, Amanda Heslegrave, Vandana Gupta, Martha Foiani, Anna Villar‐Piqué, Matthias Schmitz, Sylvain Lehmann, Charlotte Teunissen, Kaj Blennow, Henrik Zetterberg, Brit Mollenhauer, Inga Zerr, Franc Llorens
Published 2018-01-01

Differential role of CSF fatty acid binding protein 3, α-synuclein, and Alzheimer’s disease core biomarkers in Lewy body disorders and Alzheimer’s dementia

by Davide Chiasserini, Leonardo Biscetti, Paolo Eusebi, Nicola Salvadori, Giulia Frattini, Simone Simoni, Naomi De Roeck, Nicola Tambasco, Erik Stoops, Hugo Vanderstichele, Sebastiaan Engelborghs, Brit Mollenhauer, Paolo Calabresi, Lucilla Parnetti
Published 2017-07-01

A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol

by Christoph Gerdes, Natalia Waal, Thomas Offner, Eugenio F. Fornasiero, Nora Wender, Hannes Verbarg, Ivan Manzini, Claudia Trenkwalder, Brit Mollenhauer, Timo Strohäker, Markus Zweckstetter, Stefan Becker, Silvio O. Rizzoli, Fitnat Buket Basmanav, Felipe Opazo
Published 2020-06-01

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

by Nour K. Majbour, Jan O. Aasly, Eldbjørg Hustad, Mercy A. Thomas, Nishant N. Vaikath, Naser Elkum, Wilma D. J. van de Berg, Takahiko Tokuda, Brit Mollenhauer, Henk W. Berendse, Omar M. A. El-Agnaf
Published 2020-05-01

Fluid biomarkers in multiple system atrophy: A review of the MSA Biomarker Initiative

by Brice Laurens, Radu Constantinescu, Roy Freeman, Alexander Gerhard, Kurt Jellinger, Andreas Jeromin, Florian Krismer, Brit Mollenhauer, Michael G. Schlossmacher, Leslie M. Shaw, Marcel M. Verbeek, Gregor K. Wenning, Kristian Winge, Jing Zhang, Wassilios G. Meissner
Published 2015-08-01

Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson’s disease

by Lori N. Eidson, George T. Kannarkat, Christopher J. Barnum, Jianjun Chang, Jaegwon Chung, Chelsea Caspell-Garcia, Peggy Taylor, Brit Mollenhauer, Michael G. Schlossmacher, Larry Ereshefsky, Mark Yen, Catherine Kopil, Mark Frasier, Kenneth Marek, Vicki S. Hertzberg, Malú G. Tansey
Published 2017-08-01

Protein Binding Partners of Dysregulated miRNAs in Parkinson’s Disease Serum

by Wolfgang P. Ruf, Axel Freischmidt, Veselin Grozdanov, Valerie Roth, Sarah J. Brockmann, Brit Mollenhauer, Dorothea Martin, Bernhard Haslinger, Katrin Fundel-Clemens, Markus Otto, Christine von Arnim, Karlheinz Holzmann, Albert C. Ludolph, Jochen H. Weishaupt, Karin M. Danzer
Published 2021-04-01

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metabolism in Parkinson’s Disease

by Johannes Hertel, Amy C. Harms, Almut Heinken, Federico Baldini, Cyrille C. Thinnes, Enrico Glaab, Daniel A. Vasco, Maik Pietzner, Isobel D. Stewart, Nicholas J. Wareham, Claudia Langenberg, Claudia Trenkwalder, Rejko Krüger, Thomas Hankemeier, Ronan M.T. Fleming, Brit Mollenhauer, Ines Thiele
Published 2019-11-01

Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation.

by Diana F Lázaro, Eva F Rodrigues, Ramona Langohr, Hedieh Shahpasandzadeh, Thales Ribeiro, Patrícia Guerreiro, Ellen Gerhardt, Katharina Kröhnert, Jochen Klucken, Marcos D Pereira, Blagovesta Popova, Niels Kruse, Brit Mollenhauer, Silvio O Rizzoli, Gerhard H Braus, Karin M Danzer, Tiago F Outeiro
Published 2014-11-01

Rare variants in PLXNA4 and Parkinson's disease.

by Eva C Schulte, Immanuel Stahl, Darina Czamara, Daniel C Ellwanger, Sebastian Eck, Elisabeth Graf, Brit Mollenhauer, Alexander Zimprich, Peter Lichtner, Dietrich Haubenberger, Walter Pirker, Thomas Brücke, Benjamin Bereznai, Maria J Molnar, Annette Peters, Christian Gieger, Bertram Müller-Myhsok, Claudia Trenkwalder, Juliane Winkelmann
Published 2013-01-01

Niemann-Pick C disease gene mutations and age-related neurodegenerative disorders.

by Michael Zech, Georg Nübling, Florian Castrop, Angela Jochim, Eva C Schulte, Brit Mollenhauer, Peter Lichtner, Annette Peters, Christian Gieger, Thorsten Marquardt, Marie T Vanier, Philippe Latour, Hans Klünemann, Claudia Trenkwalder, Janine Diehl-Schmid, Robert Perneczky, Thomas Meitinger, Konrad Oexle, Bernhard Haslinger, Stefan Lorenzl, Juliane Winkelmann
Published 2013-01-01