Low-level alternative tRNA priming of reverse transcription of HIV-1 and SIV in vivo

by Christine M. Fennessey, Celine Camus, Taina T. Immonen, Carolyn Reid, Frank Maldarelli, Jeffrey D. Lifson, Brandon F. Keele
Published 2019-04-01

Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys

by Brandon F. Keele, Wenjun Li, Erica N. Borducchi, Joseph P. Nkolola, Peter Abbink, Bing Chen, Michael S. Seaman, Dan H. Barouch
Published 2017-06-01

Predictors of SIV recrudescence following antiretroviral treatment interruption

by Mykola Pinkevych, Christine M Fennessey, Deborah Cromer, Carolyn Reid, Charles M Trubey, Jeffrey D Lifson, Brandon F Keele, Miles P Davenport
Published 2019-10-01

Transient viral replication during analytical treatment interruptions in SIV infected macaques can alter the rebound-competent viral reservoir.

by Taina T Immonen, Christine M Fennessey, Leslie Lipkey, Abigail Thorpe, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele
Published 2021-06-01

Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation.

by Krista A Delviks-Frankenberry, Olga A Nikolaitchik, Ryan C Burdick, Robert J Gorelick, Brandon F Keele, Wei-Shau Hu, Vinay K Pathak
Published 2016-05-01

Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion.

by Ivona Pandrea, Thaidra Gaufin, Rajeev Gautam, Jan Kristoff, Daniel Mandell, David Montefiori, Brandon F Keele, Ruy M Ribeiro, Ronald S Veazey, Cristian Apetrei
Published 2011-08-01

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.

by Haiying Li, Laura E Richert-Spuhler, Tristan I Evans, Jacqueline Gillis, Michelle Connole, Jacob D Estes, Brandon F Keele, Nichole R Klatt, R Keith Reeves
Published 2014-12-01

A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host.

by Alison F Feder, Christopher Kline, Patricia Polacino, Mackenzie Cottrell, Angela D M Kashuba, Brandon F Keele, Shiu-Lok Hu, Dmitri A Petrov, Pleuni S Pennings, Zandrea Ambrose
Published 2017-05-01

Transmitted/founder simian immunodeficiency virus envelope sequences in vesicular stomatitis and Semliki forest virus vector immunized rhesus macaques.

by Ratish Gambhira, Brandon F Keele, John B Schell, Meredith J Hunter, Jason P Dufour, David C Montefiori, Haili Tang, John K Rose, Nina Rose, Preston A Marx
Published 2014-01-01

Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission.

by Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes, Gary L Griffiths, Hisataka Kobayashi, Peter L Choyke, Jeffrey D Lifson, Brandon F Keele
Published 2014-01-01

A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity.

by Mohammed Asmal, Ina Hellmann, Weimin Liu, Brandon F Keele, Alan S Perelson, Tanmoy Bhattacharya, S Gnanakaran, Marcus Daniels, Barton F Haynes, Bette T Korber, Beatrice H Hahn, George M Shaw, Norman L Letvin
Published 2011-01-01

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir.

by John K Bui, Michele D Sobolewski, Brandon F Keele, Jonathan Spindler, Andrew Musick, Ann Wiegand, Brian T Luke, Wei Shao, Stephen H Hughes, John M Coffin, Mary F Kearney, John W Mellors
Published 2017-03-01

DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Con...

by Melanie Thompson, Sonya L Heath, Bentley Sweeton, Kathy Williams, Pamela Cunningham, Brandon F Keele, Sharon Sen, Brent E Palmer, Nicolas Chomont, Yongxian Xu, Rahul Basu, Michael S Hellerstein, Suefen Kwa, Harriet L Robinson
Published 2016-01-01

CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART

by Valerie F. Boltz, Cristina Ceriani, Jason W. Rausch, Wei Shao, Michael J. Bale, Brandon F. Keele, Rebecca Hoh, Jeffrey M. Milush, Steve G. Deeks, Frank Maldarelli, Mary F. Kearney, John M. Coffin
Published 2021-04-01

HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.

by Natasha Wood, Tanmoy Bhattacharya, Brandon F Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, Guido Ferrari, Barton F Haynes, Andrew McMichael, George M Shaw, Beatrice H Hahn, Bette Korber, Cathal Seoighe
Published 2009-05-01

Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

by Po-Ting Liu, Brandon F. Keele, Peter Abbink, Noe B. Mercado, Jinyan Liu, Esther A. Bondzie, Abishek Chandrashekar, Erica N. Borducchi, Joseph Hesselgesser, Michael Mish, Gregory Chin, Elena Bekerman, Romas Geleziunas, Dan H. Barouch
Published 2020-10-01

A new approach for monitoring ebolavirus in wild great apes.

by Patricia E Reed, Sabue Mulangu, Kenneth N Cameron, Alain U Ondzie, Damien Joly, Magdalena Bermejo, Pierre Rouquet, Giulia Fabozzi, Michael Bailey, Zhimin Shen, Brandon F Keele, Beatrice Hahn, William B Karesh, Nancy J Sullivan
Published 2014-09-01

Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1.

by Richard E Haaland, Paulina A Hawkins, Jesus Salazar-Gonzalez, Amber Johnson, Amanda Tichacek, Etienne Karita, Olivier Manigart, Joseph Mulenga, Brandon F Keele, George M Shaw, Beatrice H Hahn, Susan A Allen, Cynthia A Derdeyn, Eric Hunter
Published 2009-01-01

African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity.

by Kevin D Raehtz, Fredrik Barrenäs, Cuiling Xu, Kathleen Busman-Sahay, Audrey Valentine, Lynn Law, Dongzhu Ma, Benjamin B Policicchio, Viskam Wijewardana, Egidio Brocca-Cofano, Anita Trichel, Michael Gale, Brandon F Keele, Jacob D Estes, Cristian Apetrei, Ivona Pandrea
Published 2020-03-01

A single gp120 residue can affect HIV-1 tropism in macaques.

by Gregory Q Del Prete, Brandon F Keele, Jeannine Fode, Keyur Thummar, Adrienne E Swanstrom, Anthony Rodriguez, Alice Raymond, Jacob D Estes, Celia C LaBranche, David C Montefiori, Vineet N KewalRamani, Jeffrey D Lifson, Paul D Bieniasz, Theodora Hatziioannou
Published 2017-09-01