Mechanical-stretch of C2C12 myoblasts inhibits expression of Toll-like receptor 3 (TLR3) and of autoantigens associated with inflammatory myopathies.

by Rong Chen, Liqiang Feng, Mo Ruan, Xinghui Liu, Sahil Adriouch, Hua Liao
Published 2013-01-01

Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

by Allan Scarpitta, Ulrich T. Hacker, Hildegard Büning, Hildegard Büning, Olivier Boyer, Olivier Boyer, Sahil Adriouch
Published 2021-08-01

T Cells of Different Developmental Stages Differ in Sensitivity to Apoptosis Induced by Extracellular NAD

by Friedrich Haag, Dunja Freese, Felix Scheublein, Wiebke Ohlrogge, Sahil Adriouch, Michel Seman, Friedrich Koch-Nolte
Published 2002-01-01

Induction of hematopoietic microchimerism by gene-modified BMT elicits antigen-specific B and T cell unresponsiveness toward gene therapy products

by Jérémie Martinet, Gwladys Bourdenet, Amine Meliani, Laetitia Jean, Sahil Adriouch, José Cohen, Federico Mingozzi, Olivier Boyer
Published 2016-09-01

Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells.

by Emilie Franck, Carole Bonneau, Laetitia Jean, Jean-Paul Henry, Yann Lacoume, Anna Salvetti, Olivier Boyer, Sahil Adriouch
Published 2012-01-01

Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

by Nicole Schwarz, Laurent Drouot, Annette Nicke, Ralf Fliegert, Olivier Boyer, Andreas H Guse, Friedrich Haag, Sahil Adriouch, Friedrich Koch-Nolte
Published 2012-01-01

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

by Mohamed Habbeddine, Christophe Verthuy, Olivia Rastoin, Lionel Chasson, Magali Bebien, Marc Bajenoff, Sahil Adriouch, Joke M.M. den Haan, Josef M. Penninger, Toby Lawrence
Published 2017-11-01

Evaluation of P2X7 Receptor Function in Tumor Contexts Using rAAV Vector and Nanobodies (AAVnano)

by Mélanie Demeules, Allan Scarpitta, Catalina Abad, Henri Gondé, Romain Hardet, Carolina Pinto-Espinoza, Anna Marei Eichhoff, Waldemar Schäfer, Friedrich Haag, Friedrich Koch-Nolte, Sahil Adriouch
Published 2020-09-01

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors

by Anna Marei Eichhoff, Kathleen Börner, Birte Albrecht, Waldemar Schäfer, Natalie Baum, Friedrich Haag, Jakob Körbelin, Martin Trepel, Ingke Braren, Dirk Grimm, Sahil Adriouch, Friedrich Koch-Nolte
Published 2019-12-01

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model.

by Clément Guillou, Céline Derambure, Manuel Fréret, Mathieu Verdet, Gilles Avenel, Marie-Laure Golinski, Jean-Christophe Sabourin, François Le Loarer, Sahil Adriouch, Olivier Boyer, Thierry Lequerré, Olivier Vittecoq
Published 2015-01-01

A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo

by Henri Gondé, Henri Gondé, Mélanie Demeules, Romain Hardet, Allan Scarpitta, Marten Junge, Carolina Pinto-Espinoza, Rémi Varin, Rémi Varin, Friedrich Koch-Nolte, Olivier Boyer, Olivier Boyer, Sahil Adriouch
Published 2021-08-01

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

by Björn Rissiek, Stephan Menzel, Mario Leutert, Maike Cordes, Sarah Behr, Larissa Jank, Peter Ludewig, Mathias Gelderblom, Anne Rissiek, Sahil Adriouch, Friedrich Haag, Michael O. Hottiger, Friedrich Koch-Nolte, Tim Magnus
Published 2017-11-01

Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy

by Mohamad Hamieh, Jean-François Chatillon, Estelle Dupel, Florence Bayeux, Emilie Fauquembergue, Pauline Maby, Aurelie Drouet, Anne-Bénédicte Duval-Modeste, Sahil Adriouch, Olivier Boyer, Olivier Boyer, Jean-Baptiste Latouche, Jean-Baptiste Latouche
Published 2021-09-01

Chromosomal Instability but Lack of Transformation in Human Myoblast Preparations

by Aurélie Bisson, Stéphanie Le Corre, Géraldine Joly-Helas, Pascal Chambon, Laetitia Demoulins, Laetitia Jean, Sahil Adriouch, Laurent Drouot, Camille Giverne, Francis Roussel, Serge Jacquot, Christelle Doucet, Francis Michot, Marek Lamacz, Thierry Frébourg, Jean-Michel Flaman, Olivier Boyer
Published 2014-12-01

A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy

by Laetitia Douguet, Serena Janho dit Hreich, Jonathan Benzaquen, Laetitia Seguin, Thierry Juhel, Xavier Dezitter, Christophe Duranton, Bernhard Ryffel, Jean Kanellopoulos, Cecile Delarasse, Nicolas Renault, Christophe Furman, Germain Homerin, Chloé Féral, Julien Cherfils-Vicini, Régis Millet, Sahil Adriouch, Alina Ghinet, Paul Hofman, Valérie Vouret-Craviari
Published 2021-01-01

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

by Juan José Martínez-García, Helios Martínez-Banaclocha, Diego Angosto-Bazarra, Carlos de Torre-Minguela, Alberto Baroja-Mazo, Cristina Alarcón-Vila, Laura Martínez-Alarcón, Joaquín Amores-Iniesta, Fátima Martín-Sánchez, Giovanni A. Ercole, Carlos M. Martínez, Ada González-Lisorge, José Fernández-Pacheco, Piedad Martínez-Gil, Sahil Adriouch, Friedrich Koch-Nolte, Juan Luján, Francisco Acosta-Villegas, Pascual Parrilla, Carlos García-Palenciano, Pablo Pelegrin
Published 2019-06-01