Key Inflammatory Processes in Human NASH Are Reflected in Ldlr−/−.Leiden Mice: A Translational Gene Profiling Study

by Martine C. Morrison, Robert Kleemann, Robert Kleemann, Arianne van Koppen, Roeland Hanemaaijer, Lars Verschuren
Published 2018-02-01

Cell-based therapies for experimental chronic kidney disease: a systematic review and meta-analysis

by Diana A. Papazova, Nynke R. Oosterhuis, Hendrik Gremmels, Arianne van Koppen, Jaap A. Joles, Marianne C. Verhaar
Published 2015-03-01

Maintenance of hypertensive hemodynamics does not depend on ROS in established experimental chronic kidney disease.

by Diana A Papazova, Arianne van Koppen, Maarten P Koeners, Ronald L Bleys, Marianne C Verhaar, Jaap A Joles
Published 2014-01-01

Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease.

by Arianne van Koppen, Jaap A Joles, Bas W M van Balkom, Sai Kiang Lim, Dominique de Kleijn, Rachel H Giles, Marianne C Verhaar
Published 2012-01-01

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

by Martine C. Morrison, Gopala K. Yakala, Wen Liang, Peter Y. Wielinga, Kanita Salic, Arianne van Koppen, Tushar Tomar, Robert Kleemann, Peter Heeringa, Teake Kooistra
Published 2017-06-01

Healthy Bone Marrow Cells Reduce Progression of Kidney Failure Better than CKD Bone Marrow Cells in Rats with Established Chronic Kidney Disease

by Arianne Van Koppen, Jaap A. Joles, Lennart G. Bongartz, Jens Van Den Brandt, Holger M. Reichardt, Roel Goldschmeding, Tri Q. Nguyen, Marianne C. Verhaar M.D., Ph.D.
Published 2012-10-01

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets

by Daniela Iaconis, Maria Monti, Mario Renda, Arianne van Koppen, Roberta Tammaro, Marco Chiaravalli, Flora Cozzolino, Paola Pignata, Claudia Crina, Piero Pucci, Alessandra Boletta, Vincenzo Belcastro, Rachel H. Giles, Enrico Maria Surace, Simone Gallo, Mario Pende, Brunella Franco
Published 2017-04-01

The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis

by Marianne G. Pouwer, Suvi E. Heinonen, Margareta Behrendt, Anne-Christine Andréasson, Arianne van Koppen, Aswin L. Menke, Elsbet J. Pieterman, Anita M. van den Hoek, J. Wouter Jukema, Brendan Leighton, Ann-Cathrine Jönsson-Rylander, Hans M. G. Princen
Published 2019-01-01

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr‐/‐.Leiden Mice

by Martine C. Morrison, Lars Verschuren, Kanita Salic, Joanne Verheij, Aswin Menke, Peter Y. Wielinga, Marta Iruarrizaga‐Lejarreta, Laurent Gole, Wei‐Miao Yu, Scott Turner, Martien P.M. Caspers, Ibon Martínez‐Arranz, Elsbet Pieterman, Reinout Stoop, Arianne van Koppen, Anita M. van den Hoek, José M. Mato, Roeland Hanemaaijer, Cristina Alonso, Robert Kleemann
Published 2018-12-01

Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

by Arianne van Koppen, Lars Verschuren, Anita M. van den Hoek, Joanne Verheij, Martine C. Morrison, Kelvin Li, Hiroshi Nagabukuro, Adalberto Costessi, Martien P.M. Caspers, Tim J. van den Broek, John Sagartz, Cornelis Kluft, Carine Beysen, Claire Emson, Alain J. van Gool, Roel Goldschmeding, Reinout Stoop, Ivana Bobeldijk-Pastorova, Scott M. Turner, Guido Hanauer, Roeland Hanemaaijer
Published 2018-01-01