Generation of in situ sequencing based OncoMaps to spatially resolve gene expression profiles of diagnostic and prognostic markers in breast cancerResearch in Context

by Jessica Svedlund, Carina Strell, Xiaoyan Qian, Kilian J.C. Zilkens, Nicholas P. Tobin, Jonas Bergh, Anieta M. Sieuwerts, Mats Nilsson
Published 2019-10-01

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

by Anieta M. Sieuwerts, Márcia A. Inda, Marcel Smid, Henk van Ooijen, Anja van de Stolpe, John W. M. Martens, Wim F. J. Verhaegh
Published 2020-03-01

<i>APOBEC3B</i> Gene Expression in Ductal Carcinoma In Situ and Synchronous Invasive Breast Cancer

by Anieta M. Sieuwerts, Shusma C. Doebar, Vanja de Weerd, Esther I. Verhoef, Corine M. Beauford, Marie C. Agahozo, John W.M. Martens, Carolien H.M. van Deurzen
Published 2019-07-01

The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.

by Jingjing Liu, Anieta M Sieuwerts, Maxime P Look, Michelle van der Vlugt-Daane, Marion E Meijer-van Gelder, John A Foekens, Antoinette Hollestelle, John W M Martens
Published 2016-01-01

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

by Anieta M. Sieuwerts, M\u00e1rcia A. Inda, Marcel Smid, Henk van Ooijen, Anja van de Stolpe, John W. M. Martens, Wim F. J. Verhaegh
Published 2020-03-01

A Method to Correlate mRNA Expression Datasets Obtained from Fresh Frozen and Formalin-Fixed, Paraffin-Embedded Tissue Samples: A Matter of Thresholds.

by Dana A M Mustafa, Anieta M Sieuwerts, Marcel Smid, Vania de Weerd, Marcel van der Weiden, Marion E Meijer-van Gelder, John W M Martens, John A Foekens, Johan M Kros
Published 2015-01-01

Progressive APOBEC3B mRNA expression in distant breast cancer metastases.

by Anieta M Sieuwerts, Willemijne A M E Schrijver, Simone U Dalm, Vanja de Weerd, Cathy B Moelans, Natalie Ter Hoeve, Paul J van Diest, John W M Martens, Carolien H M van Deurzen
Published 2017-01-01

Prognostic Impact of HER2 and ER Status of Circulating Tumor Cells in Metastatic Breast Cancer Patients with a HER2-Negative Primary Tumor

by Nick Beije, Wendy Onstenk, Jaco Kraan, Anieta M. Sieuwerts, Paul Hamberg, Luc Y. Dirix, Anja Brouwer, Felix E. de Jongh, Agnes Jager, Caroline M. Seynaeve, Ngoc M. Van, John A. Foekens, John W.M. Martens, Stefan Sleijfer
Published 2016-11-01

Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4

by Jonas Nørskov Søndergaard, Simon J. van Heeringen, Maaike W. G. Looman, Chunling Tang, Vassilis Triantis, Pauline Louche, Eva M. Janssen-Megens, Anieta M. Sieuwerts, John W. M. Martens, Colin Logie, Hendrik G. Stunnenberg, Marleen Ansems, Gosse J. Adema
Published 2018-06-01

Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer

by Tommaso De Marchi, Mieke A. Timmermans, Anieta M. Sieuwerts, Marcel Smid, Maxime P. Look, Nicolai Grebenchtchikov, Fred C. G. J. Sweep, Jan G. Smits, Viktor Magdolen, Carolien H. M. van Deurzen, John A. Foekens, Arzu Umar, John W. Martens
Published 2017-05-01

Prospects of Targeting the Gastrin Releasing Peptide Receptor and Somatostatin Receptor 2 for Nuclear Imaging and Therapy in Metastatic Breast Cancer.

by Simone U Dalm, Willemijne A M E Schrijver, Anieta M Sieuwerts, Maxime P Look, Angelique C J Ziel-van der Made, Vanja de Weerd, John W Martens, Paul J van Diest, Marion de Jong, Carolien H M van Deurzen
Published 2017-01-01

Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

by Silvia R. Vitale, Jean A. Helmijr, Marjolein Gerritsen, Hicret Coban, Lisanne F. van Dessel, Nick Beije, Michelle van der Vlugt-Daane, Paolo Vigneri, Anieta M. Sieuwerts, Natasja Dits, Martin E. van Royen, Guido Jenster, Stefan Sleijfer, Martijn Lolkema, John W. M. Martens, Maurice P. H. M. Jansen
Published 2021-03-01

High mRNA expression of splice variant SYK short correlates with hepatic disease progression in chemonaive lymph node negative colon cancer patients.

by Robert R J Coebergh van den Braak, Anieta M Sieuwerts, Raju Kandimalla, Zarina S Lalmahomed, Sandra I Bril, Anne van Galen, Marcel Smid, Katharina Biermann, J Han J M van Krieken, Wigard P Kloosterman, John A Foekens, Ajay Goel, John W M Martens, Jan N M IJzermans, MATCH study group
Published 2017-01-01

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

by Nick Beije, Anieta M. Sieuwerts, Jaco Kraan, Ngoc M. Van, Wendy Onstenk, Silvia R. Vitale, Michelle van derVlugt‐Daane, Luc Y. Dirix, Anja Brouwer, Paul Hamberg, Felix E. deJongh, Agnes Jager, Caroline M. Seynaeve, Maurice P. H. M. Jansen, John A. Foekens, John W. M. Martens, Stefan Sleijfer
Published 2018-01-01

Circulating Tumor Cell Enumeration and Characterization in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Cabazitaxel

by Ingeborg E. de Kruijff, Anieta M. Sieuwerts, Wendy Onstenk, Jaco Kraan, Marcel Smid, Mai N. Van, Michelle van der Vlugt-Daane, Esther Oomen-de Hoop, Ron H.J. Mathijssen, Martijn P. Lolkema, Ronald de Wit, Paul Hamberg, Hielke J. Meulenbeld, Aart Beeker, Geert-Jan Creemers, John W.M. Martens, Stefan Sleijfer
Published 2019-08-01

AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel

by Anieta M. Sieuwerts, Wendy Onstenk, Jaco Kraan, Corine M. Beaufort, Mai Van, Bram De Laere, Luc Y. Dirix, Paul Hamberg, Aart Beeker, Hielke J. Meulenbeld, Geert‐Jan Creemers, Wytske M. vanWeerden, Guido W. Jenster, Annemieke J. M. Nieuweboer, Ron H. J. Mathijssen, Ronald deWit, John W. M. Martens, Stefan Sleijfer
Published 2019-08-01

Gene length corrected trimmed mean of M-values (GeTMM) processing of RNA-seq data performs similarly in intersample analyses while improving intrasample comparisons

by Marcel Smid, Robert R. J. Coebergh van den Braak, Harmen J. G. van de Werken, Job van Riet, Anne van Galen, Vanja de Weerd, Michelle van der Vlugt-Daane, Sandra I. Bril, Zarina S. Lalmahomed, Wigard P. Kloosterman, Saskia M. Wilting, John A. Foekens, Jan N. M. IJzermans, on behalf of the MATCH study group, John W. M. Martens, Anieta M. Sieuwerts
Published 2018-06-01

The topography of mutational processes in breast cancer genomes

by Sandro Morganella, Ludmil B. Alexandrov, Dominik Glodzik, Xueqing Zou, Helen Davies, Johan Staaf, Anieta M. Sieuwerts, Arie B. Brinkman, Sancha Martin, Manasa Ramakrishna, Adam Butler, Hyung-Yong Kim, Åke Borg, Christos Sotiriou, P. Andrew Futreal, Peter J. Campbell, Paul N. Span, Steven Van Laere, Sunil R. Lakhani, Jorunn E. Eyfjord, Alastair M. Thompson, Hendrik G. Stunnenberg, Marc J. van de Vijver, John W. M. Martens, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gu Kong, Gilles Thomas, Julian Sale, Cristina Rada, Michael R. Stratton, Ewan Birney, Serena Nik-Zainal
Published 2016-05-01

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

by Marcel Smid, F. Germán Rodríguez-González, Anieta M. Sieuwerts, Roberto Salgado, Wendy J. C. Prager-Van der Smissen, Michelle van der Vlugt-Daane, Anne van Galen, Serena Nik-Zainal, Johan Staaf, Arie B. Brinkman, Marc J. van de Vijver, Andrea L. Richardson, Aquila Fatima, Kim Berentsen, Adam Butler, Sancha Martin, Helen R. Davies, Reno Debets, Marion E. Meijer-Van Gelder, Carolien H. M. van Deurzen, Gaëtan MacGrogan, Gert G. G. M. Van den Eynden, Colin Purdie, Alastair M. Thompson, Carlos Caldas, Paul N. Span, Peter T. Simpson, Sunil R. Lakhani, Steven Van Laere, Christine Desmedt, Markus Ringnér, Stefania Tommasi, Jorunn Eyford, Annegien Broeks, Anne Vincent-Salomon, P. Andrew Futreal, Stian Knappskog, Tari King, Gilles Thomas, Alain Viari, Anita Langerød, Anne-Lise Børresen-Dale, Ewan Birney, Hendrik G. Stunnenberg, Mike Stratton, John A. Foekens, John W. M. Martens
Published 2016-09-01

Ancestry-shift refinement mapping of the C6orf97-ESR1 breast cancer susceptibility locus.

by Simon N Stacey, Patrick Sulem, Carlo Zanon, Sigurjon A Gudjonsson, Gudmar Thorleifsson, Agnar Helgason, Aslaug Jonasdottir, Soren Besenbacher, Jelena P Kostic, James D Fackenthal, Dezheng Huo, Clement Adebamowo, Temidayo Ogundiran, Janet E Olson, Zachary S Fredericksen, Xianshu Wang, Maxime P Look, Anieta M Sieuwerts, John W M Martens, Isabel Pajares, Maria D Garcia-Prats, Jose M Ramon-Cajal, Ana de Juan, Angeles Panadero, Eugenia Ortega, Katja K H Aben, Sita H Vermeulen, Fatemeh Asadzadeh, K C Anton van Engelenburg, Sara Margolin, Chen-Yang Shen, Pei-Ei Wu, Asta Försti, Per Lenner, Roger Henriksson, Robert Johansson, Kerstin Enquist, Göran Hallmans, Thorvaldur Jonsson, Helgi Sigurdsson, Kristin Alexiusdottir, Julius Gudmundsson, Asgeir Sigurdsson, Michael L Frigge, Larus Gudmundsson, Kristleifur Kristjansson, Bjarni V Halldorsson, Unnur Styrkarsdottir, Jeffrey R Gulcher, Kari Hemminki, Annika Lindblom, Lambertus A Kiemeney, Jose I Mayordomo, John A Foekens, Fergus J Couch, Olufunmilayo I Olopade, Daniel F Gudbjartsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Oskar T Johannsson, Kari Stefansson
Published 2010-07-01