Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium

by Peter McErlean, Peter McErlean, Audrey Kelly, Audrey Kelly, Jaideep Dhariwal, Jaideep Dhariwal, Max Kirtland, Max Kirtland, Julie Watson, Julie Watson, Ismael Ranz, Ismael Ranz, Janet Smith, Alka Saxena, David J. Cousins, David J. Cousins, Antoon Van Oosterhout, Roberto Solari, Roberto Solari, Michael R. Edwards, Michael R. Edwards, Sebastian L. Johnston, Sebastian L. Johnston, Paul Lavender, Paul Lavender
Published 2020-12-01

GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage

by Lauren A. Callender, Johannes Schroth, Elizabeth C. Carroll, Conor Garrod-Ketchley, Lisa E. L. Romano, Eleanor Hendy, Audrey Kelly, Paul Lavender, Arne N. Akbar, J. Paul Chapple, Sian M. Henson
Published 2021-06-01

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

by Arnulf Hertweck, Catherine M. Evans, Malihe Eskandarpour, Jonathan C.H. Lau, Kristine Oleinika, Ian Jackson, Audrey Kelly, John Ambrose, Peter Adamson, David J. Cousins, Paul Lavender, Virginia L. Calder, Graham M. Lord, Richard G. Jenner
Published 2016-06-01

Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism

by Giuseppina Arbore, Erin E. West, Jubayer Rahman, Gaelle Le Friec, Nathalie Niyonzima, Mehdi Pirooznia, Ilker Tunc, Polychronis Pavlidis, Nicholas Powell, Yuesheng Li, Poching Liu, Aude Servais, Lionel Couzi, Veronique Fremeaux-Bacchi, Leo Placais, Alastair Ferraro, Patrick R. Walsh, David Kavanagh, Behdad Afzali, Paul Lavender, Helen J. Lachmann, Claudia Kemper
Published 2018-10-01

The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells

by Esperanza Perucha, Rossella Melchiotti, Jack A Bibby, Wing Wu, Klaus Stensgaard Frederiksen, Ceri A. Roberts, Zoe Hall, Gaelle LeFriec, Kevin A. Robertson, Paul Lavender, Jens Gammeltoft Gerwien, Leonie S. Taams, Julian L. Griffin, Emanuele de Rinaldis, Lisa G. M. van Baarsen, Claudia Kemper, Peter Ghazal, Andrew P. Cope
Published 2019-01-01