synthesis Molecular Docking Simulation SAR Structure-Activity Relationship Synthesis Thiosemicarbazide chemistry molecular docking structure activity relation ACETYLCHOLINESTERASE ANALOGS Acetylcholinesterase Alpha-glucosidase Alzheimer Disease Alzheimer disease BETA-GLUCURONIDASE BIOLOGICAL EVALUATION Benzimidazoles Butyrylcholinesterase Cholinesterase Inhibitors DERIVATIVES Glycoside Hydrolase Inhibitors Humans IN-VITRO EVALUATION Molecular Structure Molecular docking Molecular docking study POTENTIAL INHIBITORS QSAR RHINOVIRUS