chemistry human 387 Humans 376 Article 334 metabolism 244 controlled study 243 nonhuman 191 Animals 171 animal 171 procedures 159 unclassified drug 154 drug effect 132 male 118 Male 108 genetics 108 plant extract 104 Plant Extracts 99 female 91 Female 85 in vitro study 81 isolation and purification 76 antioxidant 73 Antioxidants 72 chemical structure 71 molecular docking 66 mouse 63 water 62 adult 60 animal experiment 58 pH 57